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Items: 1 to 20 of 44

1.

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis.

Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T.

J Exp Med. 2009 May 11;206(5):1089-102. doi: 10.1084/jem.20081605. Epub 2009 Apr 27.

2.

Fine tuning the immune response with PI3K.

Fruman DA, Bismuth G.

Immunol Rev. 2009 Mar;228(1):253-72. doi: 10.1111/j.1600-065X.2008.00750.x. Review.

PMID:
19290933
3.

Drug discovery approaches targeting the PI3K/Akt pathway in cancer.

Garcia-Echeverria C, Sellers WR.

Oncogene. 2008 Sep 18;27(41):5511-26. doi: 10.1038/onc.2008.246. Review.

PMID:
18794885
4.

Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis.

Oka M, Iwata C, Suzuki HI, Kiyono K, Morishita Y, Watabe T, Komuro A, Kano MR, Miyazono K.

Blood. 2008 May 1;111(9):4571-9. doi: 10.1182/blood-2007-10-120337. Epub 2008 Feb 29.

5.

Novel biochemical pathways of endoglin in vascular cell physiology.

Bernabeu C, Conley BA, Vary CP.

J Cell Biochem. 2007 Dec 15;102(6):1375-88. Review.

6.

Endoglin is required for myogenic differentiation potential of neural crest stem cells.

Mancini ML, Verdi JM, Conley BA, Nicola T, Spicer DB, Oxburgh LH, Vary CP.

Dev Biol. 2007 Aug 15;308(2):520-33. Epub 2007 Jun 16.

7.

Lymphatic development in mouse small intestine.

Kim KE, Sung HK, Koh GY.

Dev Dyn. 2007 Jul;236(7):2020-5.

8.

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.

Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J.

Cell. 2007 Jun 1;129(5):957-68.

9.

T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.

Deane JA, Kharas MG, Oak JS, Stiles LN, Luo J, Moore TI, Ji H, Rommel C, Cantley LC, Lane TE, Fruman DA.

Blood. 2007 Apr 1;109(7):2894-902.

10.

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism.

Engelman JA, Luo J, Cantley LC.

Nat Rev Genet. 2006 Aug;7(8):606-19. Review.

PMID:
16847462
11.

Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis.

Schledzewski K, Falkowski M, Moldenhauer G, Metharom P, Kzhyshkowska J, Ganss R, Demory A, Falkowska-Hansen B, Kurzen H, Ugurel S, Geginat G, Arnold B, Goerdt S.

J Pathol. 2006 May;209(1):67-77.

PMID:
16482496
12.

Phosphoinositide 3-kinases as drug targets in cancer.

Stephens L, Williams R, Hawkins P.

Curr Opin Pharmacol. 2005 Aug;5(4):357-65. Review.

PMID:
15963759
13.

Vasculogenesis and angiogenesis in the mouse embryo studied using quail/mouse chimeras.

Pudliszewski M, Pardanaud L.

Int J Dev Biol. 2005;49(2-3):355-61.

14.

Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex.

Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C.

J Cell Physiol. 2005 Aug;204(2):574-84.

PMID:
15702480
15.

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature.

Mäkinen T, Adams RH, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R, Wilkinson GA.

Genes Dev. 2005 Feb 1;19(3):397-410. Erratum in: Genes Dev. 2006 Jul 1;20(13):1829.

16.

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.

Petrova TV, Karpanen T, Norrmén C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Ylä-Herttuala S, Miura N, Alitalo K.

Nat Med. 2004 Sep;10(9):974-81. Epub 2004 Aug 22.

PMID:
15322537
17.

Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation.

Saharinen P, Tammela T, Karkkainen MJ, Alitalo K.

Trends Immunol. 2004 Jul;25(7):387-95. Review. No abstract available.

PMID:
15207507
18.
19.

Vasculogenesis and angiogenesis.

Patan S.

Cancer Treat Res. 2004;117:3-32. Review.

PMID:
15015550
20.

Functional significance of Tie2 signaling in the adult vasculature.

Peters KG, Kontos CD, Lin PC, Wong AL, Rao P, Huang L, Dewhirst MW, Sankar S.

Recent Prog Horm Res. 2004;59:51-71. Review.

PMID:
14749497

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