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Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells.

Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.

Cell Death Differ. 2008 Jan;15(1):171-82. Epub 2007 Oct 5.


Autophagy: from phenomenology to molecular understanding in less than a decade.

Klionsky DJ.

Nat Rev Mol Cell Biol. 2007 Nov;8(11):931-7. Review.


How to interpret LC3 immunoblotting.

Mizushima N, Yoshimori T.

Autophagy. 2007 Nov-Dec;3(6):542-5. Epub 2007 Jun 19. Review.


Cell death modalities: classification and pathophysiological implications.

Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L, Kroemer G.

Cell Death Differ. 2007 Jul;14(7):1237-43. Epub 2007 Apr 13. Review. No abstract available.


Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.

Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z.

EMBO J. 2007 Apr 4;26(7):1749-60. Epub 2007 Mar 8.


Autophagy is activated for cell survival after endoplasmic reticulum stress.

Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, Murakami T, Taniguchi M, Tanii I, Yoshinaga K, Shiosaka S, Hammarback JA, Urano F, Imaizumi K.

Mol Cell Biol. 2006 Dec;26(24):9220-31. Epub 2006 Oct 9.


Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response.

Festjens N, Vanden Berghe T, Vandenabeele P.

Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1371-87. Epub 2006 Jul 8. Review.


Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.

Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gélinas C, Fan Y, Nelson DA, Jin S, White E.

Cancer Cell. 2006 Jul;10(1):51-64.


Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.

Sroka TC, Pennington ME, Cress AE.

Carcinogenesis. 2006 Sep;27(9):1748-57. Epub 2006 Mar 14.


Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.

Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T, Tsujimoto Y.

Nature. 2005 Mar 31;434(7033):652-8.


Apoptosis-based therapies for hematologic malignancies.

Reed JC, Pellecchia M.

Blood. 2005 Jul 15;106(2):408-18. Epub 2005 Mar 29. Review.


Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.

Zhu K, Gerbino E, Beaupre DM, Mackley PA, Muro-Cacho C, Beam C, Hamilton AD, Lichtenheld MG, Kerr WG, Dalton W, Alsina M, Sebti SM.

Blood. 2005 Jun 15;105(12):4759-66. Epub 2005 Feb 22.


Inhibition of macroautophagy triggers apoptosis.

Boya P, González-Polo RA, Casares N, Perfettini JL, Dessen P, Larochette N, Métivier D, Meley D, Souquere S, Yoshimori T, Pierron G, Codogno P, Kroemer G.

Mol Cell Biol. 2005 Feb;25(3):1025-40.


Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes.

Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y.

Nat Cell Biol. 2004 Dec;6(12):1221-8. Epub 2004 Nov 21.


Calcium, ATP, and ROS: a mitochondrial love-hate triangle.

Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS.

Am J Physiol Cell Physiol. 2004 Oct;287(4):C817-33. Review.


Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals.

Turner JG, Engel R, Derderian JA, Jove R, Sullivan DM.

J Cell Sci. 2004 Jun 15;117(Pt 14):3061-71. Epub 2004 Jun 1.


Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization.

Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ.

EMBO J. 2003 Sep 1;22(17):4385-99.


Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans.

Wang X, Yang C, Chai J, Shi Y, Xue D.

Science. 2002 Nov 22;298(5598):1587-92.

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