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Items: 1 to 20 of 45

1.

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.

Zheng M, Cierpicki T, Momotani K, Artamonov MV, Derewenda U, Bushweller JH, Somlyo AV, Derewenda ZS.

BMC Struct Biol. 2009 May 21;9:36. doi: 10.1186/1472-6807-9-36.

2.

Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.

Chrencik JE, Brooun A, Zhang H, Mathews II, Hura GL, Foster SA, Perry JJ, Streiff M, Ramage P, Widmer H, Bokoch GM, Tainer JA, Weckbecker G, Kuhn P.

J Mol Biol. 2008 Jul 25;380(5):828-43. doi: 10.1016/j.jmb.2008.05.024. Epub 2008 May 17.

3.

Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex.

Sue SC, Cervantes C, Komives EA, Dyson HJ.

J Mol Biol. 2008 Jul 25;380(5):917-31. doi: 10.1016/j.jmb.2008.05.048. Epub 2008 May 29.

4.

Crucial structural role for the PH and C1 domains of the Vav1 exchange factor.

Rapley J, Tybulewicz VL, Rittinger K.

EMBO Rep. 2008 Jul;9(7):655-61. doi: 10.1038/embor.2008.80. Epub 2008 May 30.

5.

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Sternweis PC, Carter AM, Chen Z, Danesh SM, Hsiung YF, Singer WD.

Adv Protein Chem. 2007;74:189-228. Review.

PMID:
17854659
6.
7.
8.

The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activation.

Chhatriwala MK, Betts L, Worthylake DK, Sondek J.

J Mol Biol. 2007 May 18;368(5):1307-20. Epub 2007 Feb 22.

9.

Mapping ERK2-MKP3 binding interfaces by hydrogen/deuterium exchange mass spectrometry.

Zhou B, Zhang J, Liu S, Reddy S, Wang F, Zhang ZY.

J Biol Chem. 2006 Dec 15;281(50):38834-44. Epub 2006 Oct 17.

10.

The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.

Oleksy A, Opaliński Ł, Derewenda U, Derewenda ZS, Otlewski J.

J Biol Chem. 2006 Oct 27;281(43):32891-7. Epub 2006 Sep 5.

11.

Rho GTPase activating proteins in cancer phenotypes.

Kandpal RP.

Curr Protein Pept Sci. 2006 Aug;7(4):355-65. Review.

PMID:
16918449
12.

Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.

Itzen A, Pylypenko O, Goody RS, Alexandrov K, Rak A.

EMBO J. 2006 Apr 5;25(7):1445-55. Epub 2006 Mar 16.

13.

A simple method to predict protein flexibility using secondary chemical shifts.

Berjanskii MV, Wishart DS.

J Am Chem Soc. 2005 Nov 2;127(43):14970-1.

PMID:
16248604
14.

Rho GTPases: biochemistry and biology.

Jaffe AB, Hall A.

Annu Rev Cell Dev Biol. 2005;21:247-69. Review.

PMID:
16212495
15.

Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.

Zhang B, Zhang Y, Shacter E, Zheng Y.

Biochemistry. 2005 Feb 22;44(7):2566-76.

PMID:
15709769
16.

Probing the supramodular architecture of a multidomain protein: the structure of syntenin in solution.

Cierpicki T, Bushweller JH, Derewenda ZS.

Structure. 2005 Feb;13(2):319-27.

17.

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.

Rossman KL, Der CJ, Sondek J.

Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. Review.

PMID:
15688002
18.
19.

The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle.

Derewenda U, Oleksy A, Stevenson AS, Korczynska J, Dauter Z, Somlyo AP, Otlewski J, Somlyo AV, Derewenda ZS.

Structure. 2004 Nov;12(11):1955-65.

20.

Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.

Kristelly R, Gao G, Tesmer JJ.

J Biol Chem. 2004 Nov 5;279(45):47352-62. Epub 2004 Aug 25.

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