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Items: 1 to 20 of 32

1.

Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3(beta) phosphorylation in a mouse model of asthma.

Bentley JK, Deng H, Linn MJ, Lei J, Dokshin GA, Fingar DC, Bitar KN, Henderson WR Jr, Hershenson MB.

Am J Physiol Lung Cell Mol Physiol. 2009 Feb;296(2):L176-84. doi: 10.1152/ajplung.90376.2008. Epub 2008 Nov 14.

2.

Inhibition of glycogen synthase kinase-3beta is sufficient for airway smooth muscle hypertrophy.

Deng H, Dokshin GA, Lei J, Goldsmith AM, Bitar KN, Fingar DC, Hershenson MB, Bentley JK.

J Biol Chem. 2008 Apr 11;283(15):10198-207. doi: 10.1074/jbc.M800624200. Epub 2008 Feb 5.

3.

Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells.

McWhinnie R, Pechkovsky DV, Zhou D, Lane D, Halayko AJ, Knight DA, Bai TR.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L278-86. Epub 2006 Aug 18.

5.

Transforming growth factor-beta induces airway smooth muscle hypertrophy.

Goldsmith AM, Bentley JK, Zhou L, Jia Y, Bitar KN, Fingar DC, Hershenson MB.

Am J Respir Cell Mol Biol. 2006 Feb;34(2):247-54. Epub 2005 Oct 20.

6.

4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy.

Zhou L, Goldsmith AM, Bentley JK, Jia Y, Rodriguez ML, Abe MK, Fingar DC, Hershenson MB.

Am J Respir Cell Mol Biol. 2005 Aug;33(2):195-202. Epub 2005 May 18.

7.

Cardiotrophin-1 alters airway smooth muscle structure and mechanical properties in airway explants.

Zheng X, Zhou D, Seow CY, Bai TR.

Am J Physiol Lung Cell Mol Physiol. 2004 Dec;287(6):L1165-71. Epub 2004 Jul 23.

8.

Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy.

McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Dorfman AL, Longnus S, Pende M, Martin KA, Blenis J, Thomas G, Izumo S.

Mol Cell Biol. 2004 Jul;24(14):6231-40.

9.

Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation.

Halayko AJ, Kartha S, Stelmack GL, McConville J, Tam J, Camoretti-Mercado B, Forsythe SM, Hershenson MB, Solway J.

Am J Respir Cell Mol Biol. 2004 Sep;31(3):266-75. Epub 2004 Apr 22.

PMID:
15105162
10.

Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression.

Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD, Carter R, Wong HH, Cadbury PS, Fahy JV.

Am J Respir Crit Care Med. 2004 May 1;169(9):1001-6. Epub 2004 Jan 15.

PMID:
14726423
11.

Immunostimulatory DNA inhibits transforming growth factor-beta expression and airway remodeling.

Cho JY, Miller M, Baek KJ, Han JW, Nayar J, Rodriguez M, Lee SY, McElwain K, McElwain S, Raz E, Broide DH.

Am J Respir Cell Mol Biol. 2004 May;30(5):651-61. Epub 2003 Nov 14.

PMID:
14617508
12.

Expression and effects of cardiotrophin-1 (CT-1) in human airway smooth muscle cells.

Zhou D, Zheng X, Wang L, Stelmack G, Halayko AJ, Dorscheid D, Bai TR.

Br J Pharmacol. 2003 Dec;140(7):1237-44. Epub 2003 Nov 3.

13.

Phosphatidylinositol 3-kinase in angiotensin II-induced hypertrophy of vascular smooth muscle cells.

Yamakawa T, Tanaka S, Kamei J, Kadonosono K, Okuda K.

Eur J Pharmacol. 2003 Sep 30;478(1):39-46.

PMID:
14555183
14.

Airway structural alterations selectively associated with severe asthma.

Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M.

Am J Respir Crit Care Med. 2003 May 15;167(10):1360-8. Epub 2003 Jan 16.

PMID:
12531777
15.

Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation.

Leigh R, Ellis R, Wattie J, Southam DS, De Hoogh M, Gauldie J, O'Byrne PM, Inman MD.

Am J Respir Cell Mol Biol. 2002 Nov;27(5):526-35.

PMID:
12397011
16.

Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects.

Ma X, Cheng Z, Kong H, Wang Y, Unruh H, Stephens NL, Laviolette M.

Am J Physiol Lung Cell Mol Physiol. 2002 Dec;283(6):L1181-9. Epub 2002 Jun 28.

17.

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.

Fingar DC, Salama S, Tsou C, Harlow E, Blenis J.

Genes Dev. 2002 Jun 15;16(12):1472-87.

18.

Increases in collagen type I synthesis in asthma: the role of eosinophils and transforming growth factor-beta.

Nomura A, Uchida Y, Sakamoto T, Ishii Y, Masuyama K, Morishima Y, Hirano K, Sekizawa K.

Clin Exp Allergy. 2002 Jun;32(6):860-5.

PMID:
12047432
19.

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ.

Nat Cell Biol. 2001 Nov;3(11):1009-13.

PMID:
11715022
20.

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

Wang X, Li W, Williams M, Terada N, Alessi DR, Proud CG.

EMBO J. 2001 Aug 15;20(16):4370-9.

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