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Items: 1 to 20 of 68

1.

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.

Gallenne T, Gautier F, Oliver L, Hervouet E, Noël B, Hickman JA, Geneste O, Cartron PF, Vallette FM, Manon S, Juin P.

J Cell Biol. 2009 Apr 20;185(2):279-90. doi: 10.1083/jcb.200809153.

2.

Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis.

Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA.

Gastroenterology. 2009 Apr;136(4):1423-34. doi: 10.1053/j.gastro.2008.12.064. Epub 2009 Jan 6.

PMID:
19249395
3.

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.

Jabbour AM, Heraud JE, Daunt CP, Kaufmann T, Sandow J, O'Reilly LA, Callus BA, Lopez A, Strasser A, Vaux DL, Ekert PG.

Cell Death Differ. 2009 Apr;16(4):555-63. doi: 10.1038/cdd.2008.179. Epub 2008 Dec 12.

4.

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.

Chipuk JE, Fisher JC, Dillon CP, Kriwacki RW, Kuwana T, Green DR.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20327-32. doi: 10.1073/pnas.0808036105. Epub 2008 Dec 12.

5.

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

Singh R, Wang Y, Xiang Y, Tanaka KE, Gaarde WA, Czaja MJ.

Hepatology. 2009 Jan;49(1):87-96. doi: 10.1002/hep.22578.

6.

Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia.

Doege H, Grimm D, Falcon A, Tsang B, Storm TA, Xu H, Ortegon AM, Kazantzis M, Kay MA, Stahl A.

J Biol Chem. 2008 Aug 8;283(32):22186-92. doi: 10.1074/jbc.M803510200. Epub 2008 Jun 3.

7.

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury.

Hanawa N, Shinohara M, Saberi B, Gaarde WA, Han D, Kaplowitz N.

J Biol Chem. 2008 May 16;283(20):13565-77. doi: 10.1074/jbc.M708916200. Epub 2008 Mar 12.

8.

In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute.

Michalak EM, Villunger A, Adams JM, Strasser A.

Cell Death Differ. 2008 Jun;15(6):1019-29. doi: 10.1038/cdd.2008.16. Epub 2008 Feb 8.

9.

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.

Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W.

Gastroenterology. 2008 Feb;134(2):556-67. doi: 10.1053/j.gastro.2007.11.037. Epub 2007 Nov 28.

PMID:
18242221
10.

PCR-mediated deletion of plasmid DNA.

Hansson MD, Rzeznicka K, Rosenbäck M, Hansson M, Sirijovski N.

Anal Biochem. 2008 Apr 15;375(2):373-5. Epub 2007 Dec 8.

PMID:
18157935
11.

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease.

Puri P, Mirshahi F, Cheung O, Natarajan R, Maher JW, Kellum JM, Sanyal AJ.

Gastroenterology. 2008 Feb;134(2):568-76. Epub 2007 Oct 26.

PMID:
18082745
12.

Apoptosis: controlled demolition at the cellular level.

Taylor RC, Cullen SP, Martin SJ.

Nat Rev Mol Cell Biol. 2008 Mar;9(3):231-41. Review.

PMID:
18073771
13.

Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis.

Steckley D, Karajgikar M, Dale LB, Fuerth B, Swan P, Drummond-Main C, Poulter MO, Ferguson SS, Strasser A, Cregan SP.

J Neurosci. 2007 Nov 21;27(47):12989-99.

14.

Cell signaling in oxidative stress-induced liver injury.

Czaja MJ.

Semin Liver Dis. 2007 Nov;27(4):378-89. Review.

PMID:
17979074
15.

Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.

Neise D, Graupner V, Gillissen BF, Daniel PT, Schulze-Osthoff K, Jänicke RU, Essmann F.

Oncogene. 2008 Feb 28;27(10):1387-96. Epub 2007 Sep 3.

PMID:
17724463
16.

Metabolic stress signaling mediated by mixed-lineage kinases.

Jaeschke A, Davis RJ.

Mol Cell. 2007 Aug 3;27(3):498-508.

17.

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells.

Ekoff M, Kaufmann T, Engström M, Motoyama N, Villunger A, Jönsson JI, Strasser A, Nilsson G.

Blood. 2007 Nov 1;110(9):3209-17. Epub 2007 Jul 18.

18.

Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis.

Barreyro FJ, Kobayashi S, Bronk SF, Werneburg NW, Malhi H, Gores GJ.

J Biol Chem. 2007 Sep 14;282(37):27141-54. Epub 2007 Jul 11.

19.

Prolonged engraftment of human hepatocytes in mice transgenic for the deleted form of human hepatocyte growth factor.

Krishnan A, Viker K, Rietema H, Telgenkamp M, Knudsen B, Charlton M.

Hepatol Res. 2007 Oct;37(10):854-62. Epub 2007 Jun 15.

PMID:
17573952
20.

p73 supports cellular growth through c-Jun-dependent AP-1 transactivation.

Vikhanskaya F, Toh WH, Dulloo I, Wu Q, Boominathan L, Ng HH, Vousden KH, Sabapathy K.

Nat Cell Biol. 2007 Jun;9(6):698-705. Epub 2007 May 13.

PMID:
17496887

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