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Items: 14

1.

Pharmacokinetics and pharmacodynamics of endoperoxide antimalarials.

Gautam A, Ahmed T, Batra V, Paliwal J.

Curr Drug Metab. 2009 Mar;10(3):289-306. Review.

PMID:
19442090
2.

Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial.

Sagara I, Rulisa S, Mbacham W, Adam I, Sissoko K, Maiga H, Traore OB, Dara N, Dicko YT, Dicko A, Djimdé A, Jansen FH, Doumbo OK.

Malar J. 2009 Apr 14;8:63. doi: 10.1186/1475-2875-8-63.

3.

The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum.

Sirima SB, Tiono AB, Gansané A, Diarra A, Ouédraogo A, Konaté AT, Kiechel JR, Morgan CC, Olliaro PL, Taylor WR.

Malar J. 2009 Mar 16;8:48. doi: 10.1186/1475-2875-8-48.

4.

Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.

Rosenthal AS, Chen X, Liu JO, West DC, Hergenrother PJ, Shapiro TA, Posner GH.

J Med Chem. 2009 Feb 26;52(4):1198-203. doi: 10.1021/jm801484v.

5.

A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Sagara I, Diallo A, Kone M, Coulibaly M, Diawara SI, Guindo O, Maiga H, Niambele MB, Sissoko M, Dicko A, Djimde A, Doumbo OK.

Am J Trop Med Hyg. 2008 Nov;79(5):655-61.

PMID:
18981499
6.

Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate.

de Pilla Varotti F, Botelho AC, Andrade AA, de Paula RC, Fagundes EM, Valverde A, Mayer LM, Mendonça JS, de Souza MV, Boechat N, Krettli AU.

Antimicrob Agents Chemother. 2008 Nov;52(11):3868-74. doi: 10.1128/AAC.00510-08. Epub 2008 Aug 18.

7.

Efficacy and safety of dihydroartemisinin-piperaquine.

Myint HY, Ashley EA, Day NP, Nosten F, White NJ.

Trans R Soc Trop Med Hyg. 2007 Sep;101(9):858-66. Epub 2007 Jul 19. Review.

PMID:
17659311
8.

Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity.

Chen X, Chong CR, Shi L, Yoshimoto T, Sullivan DJ Jr, Liu JO.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14548-53. Epub 2006 Sep 18.

9.

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola.

Guthmann JP, Cohuet S, Rigutto C, Fortes F, Saraiva N, Kiguli J, Kyomuhendo J, Francis M, Noël F, Mulemba M, Balkan S.

Am J Trop Med Hyg. 2006 Jul;75(1):143-5.

PMID:
16837721
10.

Artemisinin-based combinations.

Ashley EA, White NJ.

Curr Opin Infect Dis. 2005 Dec;18(6):531-6. Review.

PMID:
16258328
11.

Identification of an antimalarial synthetic trioxolane drug development candidate.

Vennerstrom JL, Arbe-Barnes S, Brun R, Charman SA, Chiu FC, Chollet J, Dong Y, Dorn A, Hunziker D, Matile H, McIntosh K, Padmanilayam M, Santo Tomas J, Scheurer C, Scorneaux B, Tang Y, Urwyler H, Wittlin S, Charman WN.

Nature. 2004 Aug 19;430(7002):900-4.

12.

Artesunate combinations for treatment of malaria: meta-analysis.

Adjuik M, Babiker A, Garner P, Olliaro P, Taylor W, White N; International Artemisinin Study Group.

Lancet. 2004 Jan 3;363(9402):9-17.

PMID:
14723987
13.

Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy.

Posner GH, Paik IH, Sur S, McRiner AJ, Borstnik K, Xie S, Shapiro TA.

J Med Chem. 2003 Mar 13;46(6):1060-5.

PMID:
12620083
14.

Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer.

Jung M, Lee S, Ham J, Lee K, Kim H, Kim SK.

J Med Chem. 2003 Mar 13;46(6):987-94.

PMID:
12620075

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