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Items: 1 to 20 of 100

1.

Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect.

Veatch JR, McMurray MA, Nelson ZW, Gottschling DE.

Cell. 2009 Jun 26;137(7):1247-58. doi: 10.1016/j.cell.2009.04.014.

2.

Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.

Hess DC, Myers CL, Huttenhower C, Hibbs MA, Hayes AP, Paw J, Clore JJ, Mendoza RM, Luis BS, Nislow C, Giaever G, Costanzo M, Troyanskaya OG, Caudy AA.

PLoS Genet. 2009 Mar;5(3):e1000407. doi: 10.1371/journal.pgen.1000407. Epub 2009 Mar 20.

3.

Population genomics of domestic and wild yeasts.

Liti G, Carter DM, Moses AM, Warringer J, Parts L, James SA, Davey RP, Roberts IN, Burt A, Koufopanou V, Tsai IJ, Bergman CM, Bensasson D, O'Kelly MJ, van Oudenaarden A, Barton DB, Bailes E, Nguyen AN, Jones M, Quail MA, Goodhead I, Sims S, Smith F, Blomberg A, Durbin R, Louis EJ.

Nature. 2009 Mar 19;458(7236):337-41. doi: 10.1038/nature07743. Epub 2009 Feb 11.

4.

Learning a prior on regulatory potential from eQTL data.

Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, Pe'er D, Koller D.

PLoS Genet. 2009 Jan;5(1):e1000358. doi: 10.1371/journal.pgen.1000358. Epub 2009 Jan 30.

5.

Genetic interactions between transcription factors cause natural variation in yeast.

Gerke J, Lorenz K, Cohen B.

Science. 2009 Jan 23;323(5913):498-501. doi: 10.1126/science.1166426.

6.

Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis.

Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19910-4. doi: 10.1073/pnas.0810388105. Epub 2008 Dec 9.

7.

Dominant membrane uncoupling by mutant adenine nucleotide translocase in mitochondrial diseases.

Wang X, Salinas K, Zuo X, Kucejova B, Chen XJ.

Hum Mol Genet. 2008 Dec 15;17(24):4036-44. doi: 10.1093/hmg/ddn306. Epub 2008 Sep 22.

8.

Tilting at quixotic trait loci (QTL): an evolutionary perspective on genetic causation.

Weiss KM.

Genetics. 2008 Aug;179(4):1741-56. doi: 10.1534/genetics.108.094128. Review.

9.

Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast.

Demogines A, Smith E, Kruglyak L, Alani E.

PLoS Genet. 2008 Jul 11;4(7):e1000123. doi: 10.1371/journal.pgen.1000123.

10.

The molecular basis for relative physiological functionality of the ADP/ATP carrier isoforms in Saccharomyces cerevisiae.

Smith CP, Thorsness PE.

Genetics. 2008 Jul;179(3):1285-99. doi: 10.1534/genetics.108.087700. Epub 2008 Jun 18.

11.

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks.

Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L, Bumgarner RE, Schadt EE.

Nat Genet. 2008 Jul;40(7):854-61. doi: 10.1038/ng.167. Epub 2008 Jun 15.

12.

Yeast mitochondria import ATP through the calcium-dependent ATP-Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose.

Traba J, Froschauer EM, Wiesenberger G, Satrústegui J, Del Arco A.

Mol Microbiol. 2008 Aug;69(3):570-85. doi: 10.1111/j.1365-2958.2008.06300.x. Epub 2008 Jun 28.

13.

Energetics of protein translocation into mitochondria.

Mokranjac D, Neupert W.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):758-62. doi: 10.1016/j.bbabio.2008.04.009. Epub 2008 Apr 12. Review.

14.

Pleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport.

Kucejova B, Li L, Wang X, Giannattasio S, Chen XJ.

Mol Genet Genomics. 2008 Jul;280(1):25-39. doi: 10.1007/s00438-008-0342-5. Epub 2008 Apr 23.

15.

Cell-to-cell stochastic variation in gene expression is a complex genetic trait.

Ansel J, Bottin H, Rodriguez-Beltran C, Damon C, Nagarajan M, Fehrmann S, François J, Yvert G.

PLoS Genet. 2008 Apr 11;4(4):e1000049. doi: 10.1371/journal.pgen.1000049.

16.

Genome-wide association studies for complex traits: consensus, uncertainty and challenges.

McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN.

Nat Rev Genet. 2008 May;9(5):356-69. doi: 10.1038/nrg2344. Review.

PMID:
18398418
17.

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP.

Nat Genet. 2008 May;40(5):592-9. doi: 10.1038/ng.118. Epub 2008 Apr 6.

18.

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.

Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J.

Science. 2008 May 2;320(5876):661-4. doi: 10.1126/science.1156906. Epub 2008 Apr 3.

19.

Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases.

Lill R, Mühlenhoff U.

Annu Rev Biochem. 2008;77:669-700. doi: 10.1146/annurev.biochem.76.052705.162653. Review.

PMID:
18366324
20.

The biochemistry of heme biosynthesis.

Heinemann IU, Jahn M, Jahn D.

Arch Biochem Biophys. 2008 Jun 15;474(2):238-51. doi: 10.1016/j.abb.2008.02.015. Epub 2008 Feb 21. Review.

PMID:
18314007

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