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Items: 1 to 20 of 35

1.

Tailoring T-cell receptor signals by proximal negative feedback mechanisms.

Acuto O, Di Bartolo V, Michel F.

Nat Rev Immunol. 2008 Sep;8(9):699-712. doi: 10.1038/nri2397. Review.

PMID:
18728635
2.

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs.

Zhao W, Lee C, Piganis R, Plumlee C, de Weerd N, Hertzog PJ, Schindler C.

J Immunol. 2008 Apr 15;180(8):5483-9.

3.

Ligand binding induces a conformational change in ifnar1 that is propagated to its membrane-proximal domain.

Strunk JJ, Gregor I, Becker Y, Li Z, Gavutis M, Jaks E, Lamken P, Walz T, Enderlein J, Piehler J.

J Mol Biol. 2008 Mar 28;377(3):725-39. doi: 10.1016/j.jmb.2008.01.017. Epub 2008 Jan 16.

PMID:
18294654
4.

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC.

Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030.

5.

Interferons at age 50: past, current and future impact on biomedicine.

Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, Stark GR.

Nat Rev Drug Discov. 2007 Dec;6(12):975-90. Review.

6.

The receptor of the type I interferon family.

Uzé G, Schreiber G, Piehler J, Pellegrini S.

Curr Top Microbiol Immunol. 2007;316:71-95. Review.

PMID:
17969444
7.

Upregulation of a small subset of genes drives type I interferon-induced antiviral memory.

Jaitin DA, Schreiber G.

J Interferon Cytokine Res. 2007 Aug;27(8):653-64.

PMID:
17784817
8.

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

Marijanovic Z, Ragimbeau J, van der Heyden J, Uzé G, Pellegrini S.

Biochem J. 2007 Oct 1;407(1):141-51.

9.

JAK-STAT signaling: from interferons to cytokines.

Schindler C, Levy DE, Decker T.

J Biol Chem. 2007 Jul 13;282(28):20059-63. Epub 2007 May 14. Review. No abstract available.

10.

An interferon alpha2 mutant optimized by phage display for IFNAR1 binding confers specifically enhanced antitumor activities.

Kalie E, Jaitin DA, Abramovich R, Schreiber G.

J Biol Chem. 2007 Apr 13;282(15):11602-11. Epub 2007 Feb 19.

11.

Complex modulation of cell type-specific signaling in response to type I interferons.

van Boxel-Dezaire AH, Rani MR, Stark GR.

Immunity. 2006 Sep;25(3):361-72. Review.

12.

Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity.

Slutzki M, Jaitin DA, Yehezkel TB, Schreiber G.

J Mol Biol. 2006 Jul 28;360(5):1019-30. Epub 2006 Jun 15.

PMID:
16815442
13.

Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism.

Rosner D, Stoneman V, Littlewood T, McCarthy N, Figg N, Wang Y, Tellides G, Bennett M.

Am J Pathol. 2006 Jun;168(6):2054-63.

14.

Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.

Jaitin DA, Roisman LC, Jaks E, Gavutis M, Piehler J, Van der Heyden J, Uze G, Schreiber G.

Mol Cell Biol. 2006 Mar;26(5):1888-97.

15.

Determination of the two-dimensional interaction rate constants of a cytokine receptor complex.

Gavutis M, Jaks E, Lamken P, Piehler J.

Biophys J. 2006 May 1;90(9):3345-55. Epub 2006 Feb 10.

16.

Alternative signaling pathways regulating type I interferon-induced apoptosis.

Pokrovskaja K, Panaretakis T, Grandér D.

J Interferon Cytokine Res. 2005 Dec;25(12):799-810. Review.

PMID:
16375608
17.

Mutational analysis of the IFNAR1 binding site on IFNalpha2 reveals the architecture of a weak ligand-receptor binding-site.

Roisman LC, Jaitin DA, Baker DP, Schreiber G.

J Mol Biol. 2005 Oct 21;353(2):271-81.

PMID:
16171819
18.

Mechanisms of type-I- and type-II-interferon-mediated signalling.

Platanias LC.

Nat Rev Immunol. 2005 May;5(5):375-86. Review.

PMID:
15864272
19.

T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

González PA, Carreño LJ, Coombs D, Mora JE, Palmieri E, Goldstein B, Nathenson SG, Kalergis AM.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4824-9. Epub 2005 Mar 16.

20.

A dual role of IFN-alpha in the balance between proliferation and death of human CD4+ T lymphocytes during primary response.

Dondi E, Roué G, Yuste VJ, Susin SA, Pellegrini S.

J Immunol. 2004 Sep 15;173(6):3740-7.

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