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Items: 1 to 20 of 78

2.

The ageing immune system: is it ever too old to become young again?

Dorshkind K, Montecino-Rodriguez E, Signer RA.

Nat Rev Immunol. 2009 Jan;9(1):57-62. doi: 10.1038/nri2471. Review.

PMID:
19104499
3.

B-cell diversity decreases in old age and is correlated with poor health status.

Gibson KL, Wu YC, Barnett Y, Duggan O, Vaughan R, Kondeatis E, Nilsson BO, Wikby A, Kipling D, Dunn-Walters DK.

Aging Cell. 2009 Feb;8(1):18-25. doi: 10.1111/j.1474-9726.2008.00443.x. Epub 2008 Nov 5.

4.

Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging.

Guerrettaz LM, Johnson SA, Cambier JC.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11898-902. doi: 10.1073/pnas.0805498105. Epub 2008 Aug 12.

5.

Stem cells and aging in the hematopoietic system.

Warren LA, Rossi DJ.

Mech Ageing Dev. 2009 Jan-Feb;130(1-2):46-53. doi: 10.1016/j.mad.2008.03.010. Epub 2008 Apr 8. Review.

6.

Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells.

Frasca D, Landin AM, Lechner SC, Ryan JG, Schwartz R, Riley RL, Blomberg BB.

J Immunol. 2008 Apr 15;180(8):5283-90.

7.

Mechanisms for decreased function of B cells in aged mice and humans.

Frasca D, Landin AM, Riley RL, Blomberg BB.

J Immunol. 2008 Mar 1;180(5):2741-6. Review.

8.

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.

Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA.

PLoS Biol. 2007 Aug;5(8):e201.

9.

Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA.

Frasca D, Landin AM, Alvarez JP, Blackshear PJ, Riley RL, Blomberg BB.

J Immunol. 2007 Jul 15;179(2):918-27.

10.

Correction of age-associated deficiency in germinal center response by immunization with immune complexes.

Zheng B, Switzer K, Marinova E, Wansley D, Han S.

Clin Immunol. 2007 Aug;124(2):131-7. Epub 2007 Jun 11.

PMID:
17561442
11.
12.

Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential.

Dorshkind K, Montecino-Rodriguez E.

Nat Rev Immunol. 2007 Mar;7(3):213-9. Review.

PMID:
17318232
13.

Immunosenescence of ageing.

Gruver AL, Hudson LL, Sempowski GD.

J Pathol. 2007 Jan;211(2):144-56. Review.

14.
15.

Analysis of the young and elderly variable gene repertoire in response to pneumococcal polysaccharides using a reconstituted SCID mouse model.

Shriner AK, Smithson SL, Rabquer B, Khuder S, Westerink MA.

Vaccine. 2006 Nov 30;24(49-50):7159-66. Epub 2006 Jul 12.

PMID:
16884837
16.

Gene regulatory networks and the determination of lymphoid cell fates.

Singh H, Pongubala JM.

Curr Opin Immunol. 2006 Apr;18(2):116-20. Epub 2006 Feb 10. Review.

PMID:
16473505
17.

Identification of a B-1 B cell-specified progenitor.

Montecino-Rodriguez E, Leathers H, Dorshkind K.

Nat Immunol. 2006 Mar;7(3):293-301. Epub 2006 Jan 22.

PMID:
16429139
18.

RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice.

Frasca D, Van der Put E, Landin AM, Gong D, Riley RL, Blomberg BB.

J Immunol. 2005 Nov 15;175(10):6633-44.

19.

Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults: analysis of the variable light chain repertoire.

Smithson SL, Kolibab K, Shriner AK, Srivastava N, Khuder S, Westerink MA.

Infect Immun. 2005 Nov;73(11):7477-84.

20.

Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults: analysis of the variable heavy chain repertoire.

Kolibab K, Smithson SL, Rabquer B, Khuder S, Westerink MA.

Infect Immun. 2005 Nov;73(11):7465-76.

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