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WNT signalling in the immune system: WNT is spreading its wings.

Staal FJ, Luis TC, Tiemessen MM.

Nat Rev Immunol. 2008 Aug;8(8):581-93. doi: 10.1038/nri2360. Review.


CD8+ T cell efficacy in vaccination and disease.

Appay V, Douek DC, Price DA.

Nat Med. 2008 Jun;14(6):623-8. doi: 10.1038/nm.f.1774. Review.


Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.

Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT.

Cell Stem Cell. 2008 Mar 6;2(3):274-83. doi: 10.1016/j.stem.2008.01.003.


Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.

Williams MA, Ravkov EV, Bevan MJ.

Immunity. 2008 Apr;28(4):533-45. doi: 10.1016/j.immuni.2008.02.014. Epub 2008 Mar 20.


IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy.

Hinrichs CS, Spolski R, Paulos CM, Gattinoni L, Kerstann KW, Palmer DC, Klebanoff CA, Rosenberg SA, Leonard WJ, Restifo NP.

Blood. 2008 Jun 1;111(11):5326-33. doi: 10.1182/blood-2007-09-113050. Epub 2008 Feb 14.


Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells.

Ding Y, Shen S, Lino AC, Curotto de Lafaille MA, Lafaille JJ.

Nat Med. 2008 Feb;14(2):162-9. doi: 10.1038/nm1707. Epub 2008 Feb 3.


Two betas or not two betas: regulation of asymmetric division by beta-catenin.

Mizumoto K, Sawa H.

Trends Cell Biol. 2007 Oct;17(10):465-73. Epub 2007 Oct 4. Review.


Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.

Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, Kuttler F, Malanchi I, Birchmeier W, Leutz A, Huelsken J, Held W.

Blood. 2008 Jan 1;111(1):142-9. Epub 2007 Sep 28.


Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Chang JT, Palanivel VR, Kinjyo I, Schambach F, Intlekofer AM, Banerjee A, Longworth SA, Vinup KE, Mrass P, Oliaro J, Killeen N, Orange JS, Russell SM, Weninger W, Reiner SL.

Science. 2007 Mar 23;315(5819):1687-91. Epub 2007 Mar 1.


Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells.

Wrzesinski C, Paulos CM, Gattinoni L, Palmer DC, Kaiser A, Yu Z, Rosenberg SA, Restifo NP.

J Clin Invest. 2007 Feb;117(2):492-501.


Cancer regression in patients after transfer of genetically engineered lymphocytes.

Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, Royal RE, Topalian SL, Kammula US, Restifo NP, Zheng Z, Nahvi A, de Vries CR, Rogers-Freezer LJ, Mavroukakis SA, Rosenberg SA.

Science. 2006 Oct 6;314(5796):126-9. Epub 2006 Aug 31.


CD8+ T-cell memory in tumor immunology and immunotherapy.

Klebanoff CA, Gattinoni L, Restifo NP.

Immunol Rev. 2006 Jun;211:214-24. Review.


Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

Pantaleo G, Harari A.

Nat Rev Immunol. 2006 May;6(5):417-23. Review.


Adoptive immunotherapy for cancer: building on success.

Gattinoni L, Powell DJ Jr, Rosenberg SA, Restifo NP.

Nat Rev Immunol. 2006 May;6(5):383-93. Review.


Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.

Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3304-9. Epub 2006 Feb 21.


Host-reactive CD8+ memory stem cells in graft-versus-host disease.

Zhang Y, Joe G, Hexner E, Zhu J, Emerson SG.

Nat Med. 2005 Dec;11(12):1299-305. Epub 2005 Nov 20.


Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.

Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, Palmer DC, Antony PA, Hwang ST, Rosenberg SA, Waldmann TA, Restifo NP.

Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9571-6. Epub 2005 Jun 24.

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