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Items: 1 to 20 of 39

1.

The novel "genomic pathway approach" to complex diseases: a reason for (over-)optimism?

Breitling LP, Steyerberg EW, Brenner H.

Epidemiology. 2009 Jul;20(4):500-7.

PMID:
19533849
2.

Pathway analysis by adaptive combination of P-values.

Yu K, Li Q, Bergen AW, Pfeiffer RM, Rosenberg PS, Caporaso N, Kraft P, Chatterjee N.

Genet Epidemiol. 2009 Dec;33(8):700-9. doi: 10.1002/gepi.20422.

3.

Epidemiology, data sharing, and the challenge of scientific replication.

Hernán MA, Wilcox AJ.

Epidemiology. 2009 Mar;20(2):167-8. doi: 10.1097/EDE.0b013e318196784a. No abstract available.

PMID:
19234410
4.

Biological processes, properties and molecular wiring diagrams of candidate low-penetrance breast cancer susceptibility genes.

Bonifaci N, Berenguer A, Díez J, Reina O, Medina I, Dopazo J, Moreno V, Pujana MA.

BMC Med Genomics. 2008 Dec 18;1:62. doi: 10.1186/1755-8794-1-62.

5.

Common variants at 30 loci contribute to polygenic dyslipidemia.

Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA.

Nat Genet. 2009 Jan;41(1):56-65. doi: 10.1038/ng.291. Epub 2008 Dec 7.

6.

Personal genomes: The case of the missing heritability.

Maher B.

Nature. 2008 Nov 6;456(7218):18-21. doi: 10.1038/456018a. No abstract available.

PMID:
18987709
7.

Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

Raychaudhuri S, Remmers EF, Lee AT, Hackett R, Guiducci C, Burtt NP, Gianniny L, Korman BD, Padyukov L, Kurreeman FA, Chang M, Catanese JJ, Ding B, Wong S, van der Helm-van Mil AH, Neale BM, Coblyn J, Cui J, Tak PP, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Criswell LA, Amos CI, Seldin MF, Kastner DL, Ardlie KG, Alfredsson L, Costenbader KH, Altshuler D, Huizinga TW, Shadick NA, Weinblatt ME, de Vries N, Worthington J, Seielstad M, Toes RE, Karlson EW, Begovich AB, Klareskog L, Gregersen PK, Daly MJ, Plenge RM.

Nat Genet. 2008 Oct;40(10):1216-23. doi: 10.1038/ng.233. Epub 2008 Sep 14.

8.

On the utility of gene set methods in genomewide association studies of quantitative traits.

Chasman DI.

Genet Epidemiol. 2008 Nov;32(7):658-68. doi: 10.1002/gepi.20334.

PMID:
18481796
9.

Use and misuse of the gene ontology annotations.

Rhee SY, Wood V, Dolinski K, Draghici S.

Nat Rev Genet. 2008 Jul;9(7):509-15. doi: 10.1038/nrg2363. Epub 2008 May 13. Review.

PMID:
18475267
10.

A HapMap harvest of insights into the genetics of common disease.

Manolio TA, Brooks LD, Collins FS.

J Clin Invest. 2008 May;118(5):1590-605. doi: 10.1172/JCI34772. Review.

11.

Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network.

Iossifov I, Zheng T, Baron M, Gilliam TC, Rzhetsky A.

Genome Res. 2008 Jul;18(7):1150-62. doi: 10.1101/gr.075622.107. Epub 2008 Apr 16.

12.

Variations in DNA elucidate molecular networks that cause disease.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE.

Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16.

13.

Genetics of gene expression and its effect on disease.

Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, Jonasdottir A, Styrkarsdottir U, Gretarsdottir S, Magnusson KP, Stefansson H, Fossdal R, Kristjansson K, Gislason HG, Stefansson T, Leifsson BG, Thorsteinsdottir U, Lamb JR, Gulcher JR, Reitman ML, Kong A, Schadt EE, Stefansson K.

Nature. 2008 Mar 27;452(7186):423-8. doi: 10.1038/nature06758. Epub 2008 Mar 16.

PMID:
18344981
14.

Pathway-based approaches for analysis of genomewide association studies.

Wang K, Li M, Bucan M.

Am J Hum Genet. 2007 Dec;81(6):1278-83.

15.

Enriching the analysis of genomewide association studies with hierarchical modeling.

Chen GK, Witte JS.

Am J Hum Genet. 2007 Aug;81(2):397-404. Epub 2007 Jun 26.

16.

Unravelling the pathogenesis of inflammatory bowel disease.

Xavier RJ, Podolsky DK.

Nature. 2007 Jul 26;448(7152):427-34. Review.

PMID:
17653185
17.

Drinking from the fire hose--statistical issues in genomewide association studies.

Hunter DJ, Kraft P.

N Engl J Med. 2007 Aug 2;357(5):436-9. Epub 2007 Jul 18. No abstract available.

PMID:
17634446
18.

Share and share alike: deciding how to distribute the scientific and social benefits of genomic data.

Foster MW, Sharp RR.

Nat Rev Genet. 2007 Aug;8(8):633-9. doi: 10.1038/nrg2124. Epub 2007 Jul 3. Review.

PMID:
17607307
19.

Problems with genome-wide association studies.

Shriner D, Vaughan LK, Padilla MA, Tiwari HK.

Science. 2007 Jun 29;316(5833):1840-2. No abstract available.

PMID:
17600199
20.

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease.

Lesnick TG, Papapetropoulos S, Mash DC, Ffrench-Mullen J, Shehadeh L, de Andrade M, Henley JR, Rocca WA, Ahlskog JE, Maraganore DM.

PLoS Genet. 2007 Jun;3(6):e98.

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