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Items: 1 to 20 of 35

1.

Prion protein biosynthesis and its emerging role in neurodegeneration.

Chakrabarti O, Ashok A, Hegde RS.

Trends Biochem Sci. 2009 Jun;34(6):287-95. doi: 10.1016/j.tibs.2009.03.001. Epub 2009 May 15. Review.

2.

Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration.

Rane NS, Kang SW, Chakrabarti O, Feigenbaum L, Hegde RS.

Dev Cell. 2008 Sep;15(3):359-70. doi: 10.1016/j.devcel.2008.06.015.

3.

ESCRT complexes and the biogenesis of multivesicular bodies.

Hurley JH.

Curr Opin Cell Biol. 2008 Feb;20(1):4-11. doi: 10.1016/j.ceb.2007.12.002. Epub 2008 Jan 28. Review.

4.

Role of proteasomes in disease.

Dahlmann B.

BMC Biochem. 2007 Nov 22;8 Suppl 1:S3. Review.

5.

A general model of prion strains and their pathogenicity.

Collinge J, Clarke AR.

Science. 2007 Nov 9;318(5852):930-6. Review.

PMID:
17991853
6.

Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes.

Piper RC, Luzio JP.

Curr Opin Cell Biol. 2007 Aug;19(4):459-65. Epub 2007 Aug 3. Review.

7.

Insights into prion strains and neurotoxicity.

Aguzzi A, Heikenwalder M, Polymenidou M.

Nat Rev Mol Cell Biol. 2007 Jul;8(7):552-61. Review.

PMID:
17585315
8.

Disease-associated prion protein oligomers inhibit the 26S proteasome.

Kristiansen M, Deriziotis P, Dimcheff DE, Jackson GS, Ovaa H, Naumann H, Clarke AR, van Leeuwen FW, Menéndez-Benito V, Dantuma NP, Portis JL, Collinge J, Tabrizi SJ.

Mol Cell. 2007 Apr 27;26(2):175-88.

9.

Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.

Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L.

Mol Biol Cell. 2007 Apr;18(4):1129-42. Epub 2007 Jan 17.

10.

Genome-wide atlas of gene expression in the adult mouse brain.

Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS, Byrnes EJ, Chen L, Chen L, Chen TM, Chin MC, Chong J, Crook BE, Czaplinska A, Dang CN, Datta S, Dee NR, Desaki AL, Desta T, Diep E, Dolbeare TA, Donelan MJ, Dong HW, Dougherty JG, Duncan BJ, Ebbert AJ, Eichele G, Estin LK, Faber C, Facer BA, Fields R, Fischer SR, Fliss TP, Frensley C, Gates SN, Glattfelder KJ, Halverson KR, Hart MR, Hohmann JG, Howell MP, Jeung DP, Johnson RA, Karr PT, Kawal R, Kidney JM, Knapik RH, Kuan CL, Lake JH, Laramee AR, Larsen KD, Lau C, Lemon TA, Liang AJ, Liu Y, Luong LT, Michaels J, Morgan JJ, Morgan RJ, Mortrud MT, Mosqueda NF, Ng LL, Ng R, Orta GJ, Overly CC, Pak TH, Parry SE, Pathak SD, Pearson OC, Puchalski RB, Riley ZL, Rockett HR, Rowland SA, Royall JJ, Ruiz MJ, Sarno NR, Schaffnit K, Shapovalova NV, Sivisay T, Slaughterbeck CR, Smith SC, Smith KA, Smith BI, Sodt AJ, Stewart NN, Stumpf KR, Sunkin SM, Sutram M, Tam A, Teemer CD, Thaller C, Thompson CL, Varnam LR, Visel A, Whitlock RM, Wohnoutka PE, Wolkey CK, Wong VY, Wood M, Yaylaoglu MB, Young RC, Youngstrom BL, Yuan XF, Zhang B, Zwingman TA, Jones AR.

Nature. 2007 Jan 11;445(7124):168-76. Epub 2006 Dec 6.

PMID:
17151600
11.

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway.

Kang SW, Rane NS, Kim SJ, Garrison JL, Taunton J, Hegde RS.

Cell. 2006 Dec 1;127(5):999-1013.

12.

Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein.

Orsi A, Fioriti L, Chiesa R, Sitia R.

J Biol Chem. 2006 Oct 13;281(41):30431-8. Epub 2006 Aug 14.

13.

Fluorescence protease protection of GFP chimeras to reveal protein topology and subcellular localization.

Lorenz H, Hailey DW, Lippincott-Schwartz J.

Nat Methods. 2006 Mar;3(3):205-10.

PMID:
16489338
14.
15.

Anchorless prion protein results in infectious amyloid disease without clinical scrapie.

Chesebro B, Trifilo M, Race R, Meade-White K, Teng C, LaCasse R, Raymond L, Favara C, Baron G, Priola S, Caughey B, Masliah E, Oldstone M.

Science. 2005 Jun 3;308(5727):1435-9.

16.

Protection from cytosolic prion protein toxicity by modulation of protein translocation.

Rane NS, Yonkovich JL, Hegde RS.

EMBO J. 2004 Nov 24;23(23):4550-9. Epub 2004 Nov 4.

17.

The efficiency of protein compartmentalization into the secretory pathway.

Levine CG, Mitra D, Sharma A, Smith CL, Hegde RS.

Mol Biol Cell. 2005 Jan;16(1):279-91. Epub 2004 Oct 20.

18.

The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum.

Heske J, Heller U, Winklhofer KF, Tatzelt J.

J Biol Chem. 2004 Feb 13;279(7):5435-43. Epub 2003 Nov 26.

19.

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

Mallucci G, Dickinson A, Linehan J, Klöhn PC, Brandner S, Collinge J.

Science. 2003 Oct 31;302(5646):871-4.

20.

Molecular distinction between pathogenic and infectious properties of the prion protein.

Chiesa R, Piccardo P, Quaglio E, Drisaldi B, Si-Hoe SL, Takao M, Ghetti B, Harris DA.

J Virol. 2003 Jul;77(13):7611-22.

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