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Items: 1 to 20 of 113

1.

Fibrillin microfibrils: a key role for the interbead region in elasticity.

Wang MC, Lu Y, Baldock C.

J Mol Biol. 2009 Apr 24;388(1):168-79. doi: 10.1016/j.jmb.2009.02.062. Epub 2009 Mar 4.

PMID:
19268673
2.

Microscale mechanical properties of single elastic fibers: the role of fibrillin-microfibrils.

Koenders MM, Yang L, Wismans RG, van der Werf KO, Reinhardt DP, Daamen W, Bennink ML, Dijkstra PJ, van Kuppevelt TH, Feijen J.

Biomaterials. 2009 May;30(13):2425-32. doi: 10.1016/j.biomaterials.2009.01.038. Epub 2009 Feb 13.

PMID:
19217657
3.

A homozygous mutation in ADAMTSL4 causes autosomal-recessive isolated ectopia lentis.

Ahram D, Sato TS, Kohilan A, Tayeh M, Chen S, Leal S, Al-Salem M, El-Shanti H.

Am J Hum Genet. 2009 Feb;84(2):274-8. doi: 10.1016/j.ajhg.2009.01.007. Epub 2009 Feb 5.

4.

p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice.

Carta L, Smaldone S, Zilberberg L, Loch D, Dietz HC, Rifkin DB, Ramirez F.

J Biol Chem. 2009 Feb 27;284(9):5630-6. doi: 10.1074/jbc.M806962200. Epub 2008 Dec 24.

5.

Fibrillin assembly requires fibronectin.

Sabatier L, Chen D, Fagotto-Kaufmann C, Hubmacher D, McKee MD, Annis DS, Mosher DF, Reinhardt DP.

Mol Biol Cell. 2009 Feb;20(3):846-58. doi: 10.1091/mbc.E08-08-0830. Epub 2008 Nov 26.

6.

Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.

Dabovic B, Chen Y, Choi J, Vassallo M, Dietz HC, Ramirez F, von Melchner H, Davis EC, Rifkin DB.

J Cell Physiol. 2009 Apr;219(1):14-22. doi: 10.1002/jcp.21643.

7.

Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity.

Atsawasuwan P, Mochida Y, Katafuchi M, Kaku M, Fong KS, Csiszar K, Yamauchi M.

J Biol Chem. 2008 Dec 5;283(49):34229-40. doi: 10.1074/jbc.M803142200. Epub 2008 Oct 2.

8.

Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis.

Gansner JM, Madsen EC, Mecham RP, Gitlin JD.

Dev Dyn. 2008 Oct;237(10):2844-61. doi: 10.1002/dvdy.21705.

9.

ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation.

Le Goff C, Morice-Picard F, Dagoneau N, Wang LW, Perrot C, Crow YJ, Bauer F, Flori E, Prost-Squarcioni C, Krakow D, Ge G, Greenspan DS, Bonnet D, Le Merrer M, Munnich A, Apte SS, Cormier-Daire V.

Nat Genet. 2008 Sep;40(9):1119-23. doi: 10.1038/ng.199.

10.

Heparan sulfate regulates fibrillin-1 N- and C-terminal interactions.

Cain SA, Baldwin AK, Mahalingam Y, Raynal B, Jowitt TA, Shuttleworth CA, Couchman JR, Kielty CM.

J Biol Chem. 2008 Oct 3;283(40):27017-27. doi: 10.1074/jbc.M803373200. Epub 2008 Jul 31.

11.

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.

Kinsey R, Williamson MR, Chaudhry S, Mellody KT, McGovern A, Takahashi S, Shuttleworth CA, Kielty CM.

J Cell Sci. 2008 Aug 15;121(Pt 16):2696-704. doi: 10.1242/jcs.029819. Epub 2008 Jul 24.

12.

Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems.

Weinbaum JS, Broekelmann TJ, Pierce RA, Werneck CC, Segade F, Craft CS, Knutsen RH, Mecham RP.

J Biol Chem. 2008 Sep 12;283(37):25533-43. doi: 10.1074/jbc.M709962200. Epub 2008 Jul 14.

13.

A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.

Sengle G, Ono RN, Lyons KM, B├Ąchinger HP, Sakai LY.

J Mol Biol. 2008 Sep 12;381(4):1025-39. doi: 10.1016/j.jmb.2008.06.074. Epub 2008 Jul 2.

14.

Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion.

Kantola AK, Keski-Oja J, Koli K.

Exp Cell Res. 2008 Aug 1;314(13):2488-500. doi: 10.1016/j.yexcr.2008.05.010. Epub 2008 May 29.

PMID:
18585707
15.

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome.

Brooke BS, Habashi JP, Judge DP, Patel N, Loeys B, Dietz HC 3rd.

N Engl J Med. 2008 Jun 26;358(26):2787-95. doi: 10.1056/NEJMoa0706585.

16.

Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

Schaefer L, Iozzo RV.

J Biol Chem. 2008 Aug 1;283(31):21305-9. doi: 10.1074/jbc.R800020200. Epub 2008 May 6. Review.

17.

Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assembly.

Hubmacher D, El-Hallous EI, Nelea V, Kaartinen MT, Lee ER, Reinhardt DP.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6548-53. doi: 10.1073/pnas.0706335105. Epub 2008 Apr 30.

18.

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

Chung AW, Yang HH, Radomski MW, van Breemen C.

Circ Res. 2008 Apr 25;102(8):e73-85. doi: 10.1161/CIRCRESAHA.108.174367. Epub 2008 Apr 3.

19.

Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship.

Wipff PJ, Hinz B.

Eur J Cell Biol. 2008 Sep;87(8-9):601-15. doi: 10.1016/j.ejcb.2008.01.012. Epub 2008 Mar 14. Review.

PMID:
18342983
20.

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, B├Ąchinger HP, Sakai LY.

J Biol Chem. 2008 May 16;283(20):13874-88. doi: 10.1074/jbc.M707820200. Epub 2008 Mar 13.

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