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Items: 1 to 20 of 63

1.

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells.

Kim YJ, Kim YS, Larochelle A, Renaud G, Wolfsberg TG, Adler R, Donahue RE, Hematti P, Hong BK, Roayaei J, Akagi K, Riberdy JM, Nienhuis AW, Dunbar CE, Persons DA.

Blood. 2009 May 28;113(22):5434-43. doi: 10.1182/blood-2008-10-185199. Epub 2009 Apr 1.

2.

Aldehyde dehydrogenase as a marker for stem cells.

Moreb JS.

Curr Stem Cell Res Ther. 2008 Dec;3(4):237-46. Review.

PMID:
19075754
3.

Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.

Milsom MD, Jerabek-Willemsen M, Harris CE, Schambach A, Broun E, Bailey J, Jansen M, Schleimer D, Nattamai K, Wilhelm J, Watson A, Geiger H, Margison GP, Moritz T, Baum C, Thomale J, Williams DA.

Cancer Res. 2008 Aug 1;68(15):6171-80. doi: 10.1158/0008-5472.CAN-08-0320.

4.

Development of gene therapy for blood disorders.

Nienhuis AW.

Blood. 2008 May 1;111(9):4431-44. doi: 10.1182/blood-2007-11-078121. Review.

5.

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.

Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries RK, Kiem HP.

J Clin Invest. 2008 Apr;118(4):1502-10. doi: 10.1172/JCI34371.

6.

Comparative genomic analysis using the UCSC genome browser.

Karolchik D, Bejerano G, Hinrichs AS, Kuhn RM, Miller W, Rosenbloom KR, Zweig AS, Haussler D, Kent WJ.

Methods Mol Biol. 2007;395:17-34.

PMID:
17993665
7.

Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells.

Hong S, Hwang DY, Yoon S, Isacson O, Ramezani A, Hawley RG, Kim KS.

Mol Ther. 2007 Sep;15(9):1630-9. Epub 2007 Jul 3.

8.
9.

Hematopoietic stem-cell behavior in nonhuman primates.

Shepherd BE, Kiem HP, Lansdorp PM, Dunbar CE, Aubert G, LaRochelle A, Seggewiss R, Guttorp P, Abkowitz JL.

Blood. 2007 Sep 15;110(6):1806-13. Epub 2007 May 25.

10.

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer.

Sung LY, Gao S, Shen H, Yu H, Song Y, Smith SL, Chang CC, Inoue K, Kuo L, Lian J, Li A, Tian XC, Tuck DP, Weissman SM, Yang X, Cheng T.

Nat Genet. 2006 Nov;38(11):1323-8. Epub 2006 Oct 1.

11.

Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells.

Zhang XB, Beard BC, Beebe K, Storer B, Humphries RK, Kiem HP.

PLoS Med. 2006 May;3(5):e173. Epub 2006 May 2.

12.

Genotoxicity of retroviral integration in hematopoietic cells.

Nienhuis AW, Dunbar CE, Sorrentino BP.

Mol Ther. 2006 Jun;13(6):1031-49. Epub 2006 Apr 19. Review.

13.

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.

Larochelle A, Krouse A, Metzger M, Orlic D, Donahue RE, Fricker S, Bridger G, Dunbar CE, Hematti P.

Blood. 2006 May 1;107(9):3772-8. Epub 2006 Jan 26.

14.

Survival of the fittest: in vivo selection and stem cell gene therapy.

Neff T, Beard BC, Kiem HP.

Blood. 2006 Mar 1;107(5):1751-60. Epub 2005 Nov 3. Review.

15.

Hematopoietic stem cell gene therapy: dead or alive?

Ferguson C, Larochelle A, Dunbar CE.

Trends Biotechnol. 2005 Dec;23(12):589-97. Epub 2005 Oct 10. Review.

PMID:
16216357
16.

Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.

Quinn JA, Desjardins A, Weingart J, Brem H, Dolan ME, Delaney SM, Vredenburgh J, Rich J, Friedman AH, Reardon DA, Sampson JH, Pegg AE, Moschel RC, Birch R, McLendon RE, Provenzale JM, Gururangan S, Dancey JE, Maxwell J, Tourt-Uhlig S, Herndon JE 2nd, Bigner DD, Friedman HS.

J Clin Oncol. 2005 Oct 1;23(28):7178-87.

PMID:
16192602
17.

Genome-wide analysis of retroviral DNA integration.

Bushman F, Lewinski M, Ciuffi A, Barr S, Leipzig J, Hannenhalli S, Hoffmann C.

Nat Rev Microbiol. 2005 Nov;3(11):848-58. Review.

PMID:
16175173
18.

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.

Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO; European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group.

N Engl J Med. 2005 Mar 10;352(10):987-96.

19.

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

Hematti P, Hong BK, Ferguson C, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, Wolfsberg TG, Dunbar CE, Calmels B.

PLoS Biol. 2004 Dec;2(12):e423. Epub 2004 Nov 23.

20.

Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy.

Neff T, Beard BC, Peterson LJ, Anandakumar P, Thompson J, Kiem HP.

Blood. 2005 Feb 1;105(3):997-1002. Epub 2004 Oct 19.

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