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Items: 1 to 20 of 50

1.

MicroRNAs and cancer: short RNAs go a long way.

Ventura A, Jacks T.

Cell. 2009 Feb 20;136(4):586-91. doi: 10.1016/j.cell.2009.02.005.

2.

MicroRNA-like off-target transcript regulation by siRNAs is species specific.

Burchard J, Jackson AL, Malkov V, Needham RH, Tan Y, Bartz SR, Dai H, Sachs AB, Linsley PS.

RNA. 2009 Feb;15(2):308-15. doi: 10.1261/rna.1326809.

3.

Targeting of microRNAs for therapeutics.

Stenvang J, Lindow M, Kauppinen S.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1197-200. doi: 10.1042/BST0361197.

PMID:
19021524
4.

The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities.

Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L, D'Urso L, Pagliuca A, Biffoni M, Labbaye C, Bartucci M, Muto G, Peschle C, De Maria R.

Nat Med. 2008 Nov;14(11):1271-7. doi: 10.1038/nm.1880. Epub 2008 Oct 19.

PMID:
18931683
5.

The perfect storm of tiny RNAs.

Ruvkun G.

Nat Med. 2008 Oct;14(10):1041-5. doi: 10.1038/nm1008-1041. Review. No abstract available.

PMID:
18841145
6.

Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation.

Robbins M, Judge A, Ambegia E, Choi C, Yaworski E, Palmer L, McClintock K, MacLachlan I.

Hum Gene Ther. 2008 Oct;19(10):991-9. doi: 10.1089/hum.2008.131.

PMID:
18713023
7.

The emergent role of microRNAs in molecular diagnostics of cancer.

Tam W.

J Mol Diagn. 2008 Sep;10(5):411-4. doi: 10.2353/jmoldx.2008.080067. Epub 2008 Aug 7. No abstract available.

8.

Widespread changes in protein synthesis induced by microRNAs.

Selbach M, Schwanhäusser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N.

Nature. 2008 Sep 4;455(7209):58-63. doi: 10.1038/nature07228. Epub 2008 Jul 30.

PMID:
18668040
9.

The impact of microRNAs on protein output.

Baek D, Villén J, Shin C, Camargo FD, Gygi SP, Bartel DP.

Nature. 2008 Sep 4;455(7209):64-71. doi: 10.1038/nature07242. Epub 2008 Jul 30.

10.

Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model.

Shibata MA, Morimoto J, Shibata E, Otsuki Y.

Cancer Gene Ther. 2008 Dec;15(12):776-86. doi: 10.1038/cgt.2008.43. Epub 2008 Jul 25.

PMID:
18654613
11.

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.

Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB.

Science. 2008 Jun 20;320(5883):1643-7. doi: 10.1126/science.1155390.

12.

Wandering eye for RNAi.

Rossi J, Zamore P, Kay MA.

Nat Med. 2008 Jun;14(6):611. doi: 10.1038/nm0608-611. No abstract available.

PMID:
18535575
13.

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL.

J Dermatol Sci. 2008 Sep;51(3):151-7. doi: 10.1016/j.jdermsci.2008.04.003. Epub 2008 May 20. Review.

14.

Molecular architecture of a miRNA-regulated 3' UTR.

Didiano D, Hobert O.

RNA. 2008 Jul;14(7):1297-317. doi: 10.1261/rna.1082708. Epub 2008 May 7.

15.

Gene expression silencing with 'specific' small interfering RNA goes beyond specificity - a study of key parameters to take into account in the onset of small interfering RNA off-target effects.

Vankoningsloo S, de Longueville F, Evrard S, Rahier P, Houbion A, Fattaccioli A, Gastellier M, Remacle J, Raes M, Renard P, Arnould T.

FEBS J. 2008 Jun;275(11):2738-53. doi: 10.1111/j.1742-4658.2008.06415.x. Epub 2008 Apr 16.

16.

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi.

McBride JL, Boudreau RL, Harper SQ, Staber PD, Monteys AM, Martins I, Gilmore BL, Burstein H, Peluso RW, Polisky B, Carter BJ, Davidson BL.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5868-73. doi: 10.1073/pnas.0801775105. Epub 2008 Apr 8.

17.

LNA-mediated microRNA silencing in non-human primates.

Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, Obad S, Lindholm M, Hedtjärn M, Hansen HF, Berger U, Gullans S, Kearney P, Sarnow P, Straarup EM, Kauppinen S.

Nature. 2008 Apr 17;452(7189):896-9. doi: 10.1038/nature06783. Epub 2008 Mar 26.

PMID:
18368051
18.

Adverse effects induced by short hairpin RNA expression in porcine fetal fibroblasts.

Stewart CK, Li J, Golovan SP.

Biochem Biophys Res Commun. 2008 May 23;370(1):113-7. doi: 10.1016/j.bbrc.2008.03.041. Epub 2008 Mar 20.

PMID:
18358831
19.

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Filipowicz W, Bhattacharyya SN, Sonenberg N.

Nat Rev Genet. 2008 Feb;9(2):102-14. doi: 10.1038/nrg2290. Review.

PMID:
18197166
20.

RNAi: a powerful tool to unravel hepatitis C virus-host interactions within the infectious life cycle.

Lupberger J, Brino L, Baumert TF.

J Hepatol. 2008 Mar;48(3):523-5. doi: 10.1016/j.jhep.2007.12.007. Epub 2007 Dec 31.

PMID:
18192054

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