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Items: 1 to 20 of 58

1.

Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control.

Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C, O'Shea MA, Mican J, Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM, Mellors JW, Hallahan CW, Follman DA, Connors M.

Immunity. 2008 Dec 19;29(6):1009-21. doi: 10.1016/j.immuni.2008.10.010. Epub 2008 Dec 8.

2.

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.

Varela-Rohena A, Molloy PE, Dunn SM, Li Y, Suhoski MM, Carroll RG, Milicic A, Mahon T, Sutton DH, Laugel B, Moysey R, Cameron BJ, Vuidepot A, Purbhoo MA, Cole DK, Phillips RE, June CH, Jakobsen BK, Sewell AK, Riley JL.

Nat Med. 2008 Dec;14(12):1390-5. doi: 10.1038/nm.1779. Epub 2008 Nov 9.

3.

Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors.

Lichterfeld M, Mou D, Cung TD, Williams KL, Waring MT, Huang J, Pereyra F, Trocha A, Freeman GJ, Rosenberg ES, Walker BD, Yu XG.

Blood. 2008 Nov 1;112(9):3679-87. doi: 10.1182/blood-2008-01-135442. Epub 2008 Aug 26.

4.

CD8+ T cell efficacy in vaccination and disease.

Appay V, Douek DC, Price DA.

Nat Med. 2008 Jun;14(6):623-8. doi: 10.1038/nm.f.1774. Review.

PMID:
18535580
5.

Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans.

Watkins DI, Burton DR, Kallas EG, Moore JP, Koff WC.

Nat Med. 2008 Jun;14(6):617-21. doi: 10.1038/nm.f.1759.

6.

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells.

Streeck H, Brumme ZL, Anastario M, Cohen KW, Jolin JS, Meier A, Brumme CJ, Rosenberg ES, Alter G, Allen TM, Walker BD, Altfeld M.

PLoS Med. 2008 May 6;5(5):e100. doi: 10.1371/journal.pmed.0050100.

7.

Vaccine adjuvants alter TCR-based selection thresholds.

Malherbe L, Mark L, Fazilleau N, McHeyzer-Williams LJ, McHeyzer-Williams MG.

Immunity. 2008 May;28(5):698-709. doi: 10.1016/j.immuni.2008.03.014. Epub 2008 May 1.

8.

Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

Demotte N, Stroobant V, Courtoy PJ, Van Der Smissen P, Colau D, Luescher IF, Hivroz C, Nicaise J, Squifflet JL, Mourad M, Godelaine D, Boon T, van der Bruggen P.

Immunity. 2008 Mar;28(3):414-24. doi: 10.1016/j.immuni.2008.01.011.

9.

T-cell quality in memory and protection: implications for vaccine design.

Seder RA, Darrah PA, Roederer M.

Nat Rev Immunol. 2008 Apr;8(4):247-58. doi: 10.1038/nri2274. Epub 2008 Mar 7. Review. Erratum in: Nat Rev Immunol. 2008 Jun;8(6):486.

PMID:
18323851
10.

Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy.

Rehr M, Cahenzli J, Haas A, Price DA, Gostick E, Huber M, Karrer U, Oxenius A.

J Virol. 2008 Apr;82(7):3391-404. doi: 10.1128/JVI.02383-07. Epub 2008 Jan 16.

11.

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

Sekaly RP.

J Exp Med. 2008 Jan 21;205(1):7-12. doi: 10.1084/jem.20072681. Epub 2008 Jan 14.

12.

PD-1 and its ligands in tolerance and immunity.

Keir ME, Butte MJ, Freeman GJ, Sharpe AH.

Annu Rev Immunol. 2008;26:677-704. doi: 10.1146/annurev.immunol.26.021607.090331. Review.

PMID:
18173375
13.

One step forward, two steps back--will there ever be an AIDS vaccine?

Steinbrook R.

N Engl J Med. 2007 Dec 27;357(26):2653-5. No abstract available.

14.

Cell permeabilization for the assessment of T lymphocyte polyfunctional capacity.

Papagno L, Almeida JR, Nemes E, Autran B, Appay V.

J Immunol Methods. 2007 Dec 1;328(1-2):182-8. Epub 2007 Sep 20.

PMID:
17920073
15.

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype.

Harari A, Cellerai C, Bellutti Enders F, Köstler J, Codarri L, Tapia G, Boyman O, Castro E, Gaudieri S, James I, John M, Wagner R, Mallal S, Pantaleo G.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16233-8. Epub 2007 Oct 2.

16.

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover.

Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, Bornstein E, Asher TE, Samri A, Schnuriger A, Theodorou I, Costagliola D, Rouzioux C, Agut H, Marcelin AG, Douek D, Autran B, Appay V.

J Exp Med. 2007 Oct 1;204(10):2473-85. Epub 2007 Sep 24.

17.

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A.

Nat Immunol. 2007 Oct;8(10):1049-59. Epub 2007 Sep 16.

PMID:
17873878
18.

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major.

Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, Flynn BJ, Hoff ST, Andersen P, Reed SG, Morris SL, Roederer M, Seder RA.

Nat Med. 2007 Jul;13(7):843-50. Epub 2007 Jun 10.

PMID:
17558415
19.

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses.

Precopio ML, Betts MR, Parrino J, Price DA, Gostick E, Ambrozak DR, Asher TE, Douek DC, Harari A, Pantaleo G, Bailer R, Graham BS, Roederer M, Koup RA.

J Exp Med. 2007 Jun 11;204(6):1405-16. Epub 2007 May 29.

20.

The T cell repertoire in infection and vaccination: implications for control of persistent viruses.

Davenport MP, Price DA, McMichael AJ.

Curr Opin Immunol. 2007 Jun;19(3):294-300. Epub 2007 Apr 12. Review.

PMID:
17433874

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