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Items: 1 to 20 of 46


AICAR decreases the activity of two distinct amiloride-sensitive Na+-permeable channels in H441 human lung epithelial cell monolayers.

Albert AP, Woollhead AM, Mace OJ, Baines DL.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L837-48. doi: 10.1152/ajplung.90353.2008. Epub 2008 Aug 22.


Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH.

Jasti J, Furukawa H, Gonzales EB, Gouaux E.

Nature. 2007 Sep 20;449(7160):316-23.


Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, Pucovsky V, Pellatt LJ, Scott JW, Mustard KJ, Hardie DG, Baines DL.

Br J Pharmacol. 2007 Aug;151(8):1204-15. Epub 2007 Jul 2.


Respiratory syncytial virus induces insensitivity to beta-adrenergic agonists in mouse lung epithelium in vivo.

Davis IC, Xu A, Gao Z, Hickman-Davis JM, Factor P, Sullender WM, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L281-9. Epub 2007 Apr 13.


Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction.

Ji HL, Su XF, Kedar S, Li J, Barbry P, Smith PR, Matalon S, Benos DJ.

J Biol Chem. 2006 Mar 24;281(12):8233-41. Epub 2006 Jan 19.


Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione.

Chen L, Patel RP, Teng X, Bosworth CA, Lancaster JR Jr, Matalon S.

J Biol Chem. 2006 Apr 7;281(14):9190-9. Epub 2006 Jan 17.


Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells.

Fang X, Song Y, Hirsch J, Galietta LJ, Pedemonte N, Zemans RL, Dolganov G, Verkman AS, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2006 Feb;290(2):L242-9. Epub 2005 Sep 2. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L1044.


cGMP-dependent protein kinases in drug discovery.

Schlossmann J, Hofmann F.

Drug Discov Today. 2005 May 1;10(9):627-34. Review.


cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein.

Cha B, Kim JH, Hut H, Hogema BM, Nadarja J, Zizak M, Cavet M, Lee-Kwon W, Lohmann SM, Smolenski A, Tse CM, Yun C, de Jonge HR, Donowitz M.

J Biol Chem. 2005 Apr 29;280(17):16642-50. Epub 2005 Feb 18.


cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.

Thomas CP, Campbell JR, Wright PJ, Husted RF.

Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L843-51. Epub 2004 Jun 18.


Extracellular Zn2+ activates epithelial Na+ channels by eliminating Na+ self-inhibition.

Sheng S, Perry CJ, Kleyman TR.

J Biol Chem. 2004 Jul 23;279(30):31687-96. Epub 2004 May 15.


Influenza virus inhibits ENaC and lung fluid clearance.

Chen XJ, Seth S, Yue G, Kamat P, Compans RW, Guidot D, Brown LA, Eaton DC, Jain L.

Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L366-73. Epub 2004 Apr 30.


Malnutrition impairs alveolar fluid clearance in rat lungs.

Sakuma T, Zhao Y, Sugita M, Sagawa M, Toga H, Ishibashi T, Nishio M, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1268-74. Epub 2004 Feb 20.


The role of Pre-H2 domains of alpha- and delta-epithelial Na+ channels in ion permeation, conductance, and amiloride sensitivity.

Ji HL, Bishop LR, Anderson SJ, Fuller CM, Benos DJ.

J Biol Chem. 2004 Feb 27;279(9):8428-40. Epub 2003 Dec 2.


Regulation of amiloride-sensitive Na(+) transport by basal nitric oxide.

Hardiman KM, McNicholas-Bevensee CM, Fortenberry J, Myles CT, Malik B, Eaton DC, Matalon S.

Am J Respir Cell Mol Biol. 2004 May;30(5):720-8. Epub 2003 Nov 7.


Pulmonary PKG-1 is upregulated following chronic hypoxia.

Jernigan NL, Walker BR, Resta TC.

Am J Physiol Lung Cell Mol Physiol. 2003 Sep;285(3):L634-42. Epub 2003 May 23.


cAMP-induced changes of apical membrane potentials of confluent H441 monolayers.

Lazrak A, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L443-50. Epub 2003 Apr 18.


Modulation of sodium transport in fetal alveolar epithelial cells by oxygen and corticosterone.

Thome UH, Davis IC, Nguyen SV, Shelton BJ, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2003 Feb;284(2):L376-85. Epub 2002 Nov 15.


Early changes in alveolar fluid clearance by nitric oxide after endotoxin instillation in rats.

Tsubochi H, Suzuki S, Kubo H, Ueno T, Yoshimura T, Suzuki T, Sasano H, Kondo T.

Am J Respir Crit Care Med. 2003 Jan 15;167(2):205-10.


Invited review: Active fluid clearance from the distal air spaces of the lung.

Matthay MA, Clerici C, Saumon G.

J Appl Physiol (1985). 2002 Oct;93(4):1533-41. Review.

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