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Items: 1 to 20 of 102

1.

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.

Deane R, Bell RD, Sagare A, Zlokovic BV.

CNS Neurol Disord Drug Targets. 2009 Mar;8(1):16-30. Review.

2.

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

Hawkes CA, McLaurin J.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1261-6. doi: 10.1073/pnas.0805453106. Epub 2009 Jan 21.

3.

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases.

Rosenberg GA.

Lancet Neurol. 2009 Feb;8(2):205-16. doi: 10.1016/S1474-4422(09)70016-X. Review.

PMID:
19161911
4.

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells.

Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV.

Nat Cell Biol. 2009 Feb;11(2):143-53. doi: 10.1038/ncb1819. Epub 2008 Dec 21.

5.

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.

Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV.

J Clin Invest. 2008 Dec;118(12):4002-13. doi: 10.1172/JCI36663. Epub 2008 Nov 13.

6.

Lymphatic drainage of the brain and the pathophysiology of neurological disease.

Weller RO, Djuanda E, Yow HY, Carare RO.

Acta Neuropathol. 2009 Jan;117(1):1-14. doi: 10.1007/s00401-008-0457-0. Epub 2008 Nov 11. Review.

PMID:
19002474
7.

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses.

Bertram L, Tanzi RE.

Nat Rev Neurosci. 2008 Oct;9(10):768-78. doi: 10.1038/nrn2494. Review.

PMID:
18802446
8.

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.

Hickman SE, Allison EK, El Khoury J.

J Neurosci. 2008 Aug 13;28(33):8354-60. doi: 10.1523/JNEUROSCI.0616-08.2008.

9.

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22.

10.

Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study.

Pettersen JA, Sathiyamoorthy G, Gao FQ, Szilagyi G, Nadkarni NK, St George-Hyslop P, Rogaeva E, Black SE.

Arch Neurol. 2008 Jun;65(6):790-5. doi: 10.1001/archneur.65.6.790.

PMID:
18541799
11.

Cerebral amyloid angiopathy and its relationship to Alzheimer's disease.

Thal DR, Griffin WS, de Vos RA, Ghebremedhin E.

Acta Neuropathol. 2008 Jun;115(6):599-609. doi: 10.1007/s00401-008-0366-2. Epub 2008 Mar 28. Review.

PMID:
18369648
12.

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.

Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV.

Nat Neurosci. 2008 Apr;11(4):420-2. doi: 10.1038/nn2073. Epub 2008 Mar 16.

13.

The blood-brain barrier in health and chronic neurodegenerative disorders.

Zlokovic BV.

Neuron. 2008 Jan 24;57(2):178-201. doi: 10.1016/j.neuron.2008.01.003. Review.

14.

Clearance of amyloid-beta by circulating lipoprotein receptors.

Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV.

Nat Med. 2007 Sep;13(9):1029-31. Epub 2007 Aug 12.

15.

Reduced cerebral glucose metabolism in patients at risk for Alzheimer's disease.

Hunt A, Schönknecht P, Henze M, Seidl U, Haberkorn U, Schröder J.

Psychiatry Res. 2007 Jul 15;155(2):147-54. Epub 2007 May 23.

PMID:
17524628
16.

Partial volume effect-corrected FDG PET and grey matter volume loss in patients with mild Alzheimer's disease.

Samuraki M, Matsunari I, Chen WP, Yajima K, Yanase D, Fujikawa A, Takeda N, Nishimura S, Matsuda H, Yamada M.

Eur J Nucl Med Mol Imaging. 2007 Oct;34(10):1658-69. Epub 2007 May 23.

PMID:
17520250
17.

Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer's disease and cerebral amyloid angiopathy.

Santpere G, Puig B, Ferrer I.

Neuroscience. 2007 Jun 8;146(4):1640-51. Epub 2007 Apr 19. Retraction in: Santpere G, Ferrer I. Neuroscience. 2009 Jun 30;161(2):663.

PMID:
17445990
18.

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD.

Nat Med. 2007 Apr;13(4):432-8. Epub 2007 Mar 11.

PMID:
17351623
19.

Atherosclerosis and risk for dementia.

van Oijen M, de Jong FJ, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM.

Ann Neurol. 2007 May;61(5):403-10.

PMID:
17328068
20.

Topographical distribution of cerebral amyloid angiopathy and its effect on cognitive decline are influenced by Alzheimer disease pathology.

Attems J, Quass M, Jellinger KA, Lintner F.

J Neurol Sci. 2007 Jun 15;257(1-2):49-55. Epub 2007 Feb 15.

PMID:
17306303

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