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Items: 1 to 20 of 52

1.

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL.

Brown MS, Goldstein JL.

J Lipid Res. 2009 Apr;50 Suppl:S15-27. doi: 10.1194/jlr.R800054-JLR200. Epub 2008 Oct 29. Review.

2.

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes.

Infante RE, Wang ML, Radhakrishnan A, Kwon HJ, Brown MS, Goldstein JL.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15287-92. doi: 10.1073/pnas.0807328105. Epub 2008 Sep 4.

3.

Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

Infante RE, Abi-Mosleh L, Radhakrishnan A, Dale JD, Brown MS, Goldstein JL.

J Biol Chem. 2008 Jan 11;283(2):1052-63. Epub 2007 Nov 6.

4.

Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop.

Infante RE, Radhakrishnan A, Abi-Mosleh L, Kinch LN, Wang ML, Grishin NV, Goldstein JL, Brown MS.

J Biol Chem. 2008 Jan 11;283(2):1064-75. Epub 2007 Nov 6.

5.

Structural basis of sterol binding by NPC2, a lysosomal protein deficient in Niemann-Pick type C2 disease.

Xu S, Benoff B, Liou HL, Lobel P, Stock AM.

J Biol Chem. 2007 Aug 10;282(32):23525-31. Epub 2007 Jun 14.

6.

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein.

Babalola JO, Wendeler M, Breiden B, Arenz C, Schwarzmann G, Locatelli-Hoops S, Sandhoff K.

Biol Chem. 2007 Jun;388(6):617-26.

PMID:
17552909
7.

Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.

Cheruku SR, Xu Z, Dutia R, Lobel P, Storch J.

J Biol Chem. 2006 Oct 20;281(42):31594-604. Epub 2006 Apr 10.

8.

Biomedicine. Lowering LDL--not only how low, but how long?

Brown MS, Goldstein JL.

Science. 2006 Mar 24;311(5768):1721-3. No abstract available.

PMID:
16556829
9.

Protein sensors for membrane sterols.

Goldstein JL, DeBose-Boyd RA, Brown MS.

Cell. 2006 Jan 13;124(1):35-46. Review.

10.

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins.

Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, Kirby A, Sourjina T, Peto R, Collins R, Simes R; Cholesterol Treatment Trialists' (CTT) Collaborators.

Lancet. 2005 Oct 8;366(9493):1267-78. Epub 2005 Sep 27. Erratum in: Lancet. 2005 Oct 15-21;366(9494):1358. Lancet. 2008 Jun 21;371(9630):2084.

PMID:
16214597
11.

Niemann-Pick C research from mouse to gene.

Pentchev PG.

Biochim Biophys Acta. 2004 Oct 11;1685(1-3):3-7. Review.

PMID:
15465420
12.

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs.

Adams CM, Reitz J, De Brabander JK, Feramisco JD, Li L, Brown MS, Goldstein JL.

J Biol Chem. 2004 Dec 10;279(50):52772-80. Epub 2004 Sep 27.

13.

Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain.

Ohgami N, Ko DC, Thomas M, Scott MP, Chang CC, Chang TY.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12473-8. Epub 2004 Aug 16.

14.

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport.

Sleat DE, Wiseman JA, El-Banna M, Price SM, Verot L, Shen MM, Tint GS, Vanier MT, Walkley SU, Lobel P.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5886-91. Epub 2004 Apr 7.

15.

THE INHERITANCE OF ESSENTIAL FAMILIAL HYPERCHOLESTEROLEMIA.

KHACHADURIAN AK.

Am J Med. 1964 Sep;37:402-7. No abstract available.

PMID:
14209286
16.

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L.

ROTH TF, PORTER KR.

J Cell Biol. 1964 Feb;20:313-32.

17.

Lipoprotein receptors in the nervous system.

Herz J, Bock HH.

Annu Rev Biochem. 2002;71:405-34. Epub 2001 Nov 9. Review.

PMID:
12045102
18.

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.

Horton JD, Goldstein JL, Brown MS.

J Clin Invest. 2002 May;109(9):1125-31. Review. No abstract available.

19.

Identification of HE1 as the second gene of Niemann-Pick C disease.

Naureckiene S, Sleat DE, Lackland H, Fensom A, Vanier MT, Wattiaux R, Jadot M, Lobel P.

Science. 2000 Dec 22;290(5500):2298-301.

20.

Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials.

LaRosa JC, He J, Vupputuri S.

JAMA. 1999 Dec 22-29;282(24):2340-6.

PMID:
10612322

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