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Items: 1 to 20 of 173


The multiple roles of phosphoinositide 3-kinase in mast cell biology.

Kim MS, Rådinger M, Gilfillan AM.

Trends Immunol. 2008 Oct;29(10):493-501. doi: 10.1016/ Epub 2008 Sep 3. Review.


New insights on mast cell activation via the high affinity receptor for IgE.

Rivera J, Fierro NA, Olivera A, Suzuki R.

Adv Immunol. 2008;98:85-120. doi: 10.1016/S0065-2776(08)00403-3. Review.


Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future.

Daëron M, Jaeger S, Du Pasquier L, Vivier E.

Immunol Rev. 2008 Aug;224:11-43. doi: 10.1111/j.1600-065X.2008.00666.x. Review.


Differential dephosphorylation of the FcRgamma immunoreceptor tyrosine-based activation motif tyrosines with dissimilar potential for activating Syk.

Yamashita T, Suzuki R, Backlund PS, Yamashita Y, Yergey AL, Rivera J.

J Biol Chem. 2008 Oct 17;283(42):28584-94. doi: 10.1074/jbc.M802679200. Epub 2008 Aug 19.


Mast cells and mastocytosis.

Metcalfe DD.

Blood. 2008 Aug 15;112(4):946-56. doi: 10.1182/blood-2007-11-078097. Review.


The development of allergic inflammation.

Galli SJ, Tsai M, Piliponsky AM.

Nature. 2008 Jul 24;454(7203):445-54. doi: 10.1038/nature07204. Review.


Regulation of microtubule nucleation from membranes by complexes of membrane-bound gamma-tubulin with Fyn kinase and phosphoinositide 3-kinase.

Macurek L, Dráberová E, Richterová V, Sulimenko V, Sulimenko T, Dráberová L, Marková V, Dráber P.

Biochem J. 2008 Dec 15;416(3):421-30. doi: 10.1042/BJ20080909.


A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally.

Mazuc E, Villoutreix BO, Malbec O, Roumier T, Fleury S, Leonetti JP, Dombrowicz D, Daëron M, Martineau P, Dariavach P.

J Allergy Clin Immunol. 2008 Jul;122(1):188-94, 194.e1-3. doi: 10.1016/j.jaci.2008.04.026. Epub 2008 Jun 9.


Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders.

Jensen BM, Akin C, Gilfillan AM.

Br J Pharmacol. 2008 Aug;154(8):1572-82. doi: 10.1038/bjp.2008.204. Epub 2008 May 26. Review.


Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.

Bijli KM, Fazal F, Minhajuddin M, Rahman A.

J Biol Chem. 2008 May 23;283(21):14674-84. doi: 10.1074/jbc.M802094200. Epub 2008 Mar 24.


Activation and function of the mTORC1 pathway in mast cells.

Kim MS, Kuehn HS, Metcalfe DD, Gilfillan AM.

J Immunol. 2008 Apr 1;180(7):4586-95.


Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients.

Brockow K, Jofer C, Behrendt H, Ring J.

Allergy. 2008 Feb;63(2):226-32. doi: 10.1111/j.1398-9995.2007.01569.x.


The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils.

Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P.

Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7.


Molecular perspective of antigen-mediated mast cell signaling.

Davey AM, Krise KM, Sheets ED, Heikal AA.

J Biol Chem. 2008 Mar 14;283(11):7117-27. Epub 2007 Dec 19.


"Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling.

Saxon A, Kepley C, Zhang K.

J Allergy Clin Immunol. 2008 Feb;121(2):320-5. Epub 2007 Dec 20. Review.


3D structure of Syk kinase determined by single-particle electron microscopy.

Arias-Palomo E, Recuero-Checa MA, Bustelo XR, Llorca O.

Biochim Biophys Acta. 2007 Dec;1774(12):1493-9. Epub 2007 Oct 26.


Kit- and Fc epsilonRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells.

Iwaki S, Spicka J, Tkaczyk C, Jensen BM, Furumoto Y, Charles N, Kovarova M, Rivera J, Horejsi V, Metcalfe DD, Gilfillan AM.

Cell Signal. 2008 Jan;20(1):195-205. Epub 2007 Oct 16.


TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.

Zhang J, Suzuki K, Hitomi T, Siraganian RP.

J Biol Chem. 2007 Dec 28;282(52):37669-77. Epub 2007 Oct 31.

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