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Items: 1 to 20 of 50

1.

Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis.

Saadatzadeh MR, Bijangi-Vishehsaraei K, Kapur R, Haneline LS.

Blood. 2009 Mar 19;113(12):2655-60. doi: 10.1182/blood-2008-09-181420. Epub 2009 Jan 23.

2.

Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.

Milsom MD, Jerabek-Willemsen M, Harris CE, Schambach A, Broun E, Bailey J, Jansen M, Schleimer D, Nattamai K, Wilhelm J, Watson A, Geiger H, Margison GP, Moritz T, Baum C, Thomale J, Williams DA.

Cancer Res. 2008 Aug 1;68(15):6171-80. doi: 10.1158/0008-5472.CAN-08-0320.

3.

Rapid lentiviral transduction preserves the engraftment potential of Fanca(-/-) hematopoietic stem cells.

Müller LU, Milsom MD, Kim MO, Schambach A, Schuesler T, Williams DA.

Mol Ther. 2008 Jun;16(6):1154-60. doi: 10.1038/mt.2008.67. Epub 2008 Apr 8.

4.

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.

Cell Stem Cell. 2007 Jun 7;1(1):101-12. doi: 10.1016/j.stem.2007.02.001.

5.

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.

Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries RK, Kiem HP.

J Clin Invest. 2008 Apr;118(4):1502-10. doi: 10.1172/JCI34371.

6.

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

Li J, Sejas DP, Zhang X, Qiu Y, Nattamai KJ, Rani R, Rathbun KR, Geiger H, Williams DA, Bagby GC, Pang Q.

J Clin Invest. 2007 Nov;117(11):3283-95.

7.

HOXB4's road map to stem cell expansion.

Schiedlmeier B, Santos AC, Ribeiro A, Moncaut N, Lesinski D, Auer H, Kornacker K, Ostertag W, Baum C, Mallo M, Klump H.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16952-7. Epub 2007 Oct 16.

8.

TNFalpha blockade in human diseases: an overview of efficacy and safety.

Lin J, Ziring D, Desai S, Kim S, Wong M, Korin Y, Braun J, Reed E, Gjertson D, Singh RR.

Clin Immunol. 2008 Jan;126(1):13-30. Epub 2007 Oct 4. Review.

9.

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins.

Wang W.

Nat Rev Genet. 2007 Oct;8(10):735-48. Epub 2007 Sep 4. Review.

PMID:
17768402
10.

Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice.

Sejas DP, Rani R, Qiu Y, Zhang X, Fagerlie SR, Nakano H, Williams DA, Pang Q.

J Immunol. 2007 Apr 15;178(8):5277-87.

11.

Stem cell collection and gene transfer in Fanconi anemia.

Kelly PF, Radtke S, von Kalle C, Balcik B, Bohn K, Mueller R, Schuesler T, Haren M, Reeves L, Cancelas JA, Leemhuis T, Harris R, Auerbach AD, Smith FO, Davies SM, Williams DA.

Mol Ther. 2007 Jan;15(1):211-9.

12.

Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research.

Schambach A, Galla M, Modlich U, Will E, Chandra S, Reeves L, Colbert M, Williams DA, von Kalle C, Baum C.

Exp Hematol. 2006 May;34(5):588-92.

PMID:
16647564
13.

Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells.

Zhang XB, Beard BC, Beebe K, Storer B, Humphries RK, Kiem HP.

PLoS Med. 2006 May;3(5):e173. Epub 2006 May 2.

14.

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.

Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T.

Nat Med. 2006 Apr;12(4):446-51. Epub 2006 Mar 26. Erratum in: Nat Med. 2010 Jan;16(1):129.

PMID:
16565722
15.
16.

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

Meetei AR, Medhurst AL, Ling C, Xue Y, Singh TR, Bier P, Steltenpool J, Stone S, Dokal I, Mathew CG, Hoatlin M, Joenje H, de Winter JP, Wang W.

Nat Genet. 2005 Sep;37(9):958-63. Epub 2005 Aug 21.

17.

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.

Pilat S, Carotta S, Schiedlmeier B, Kamino K, Mairhofer A, Will E, Modlich U, Steinlein P, Ostertag W, Baum C, Beug H, Klump H.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12101-6. Epub 2005 Aug 10.

18.

A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients.

Chandra S, Levran O, Jurickova I, Maas C, Kapur R, Schindler D, Henry R, Milton K, Batish SD, Cancelas JA, Hanenberg H, Auerbach AD, Williams DA.

Mol Ther. 2005 Nov;12(5):976-84. Epub 2005 Aug 9.

19.

Gene expression in response to ionizing radiation: an overview of molecular features in hematopoietic cells.

Mori M, Desaintes C.

J Biol Regul Homeost Agents. 2004 Jul-Dec;18(3-4):363-71. Review.

PMID:
15786706
20.

Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.

Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW.

Blood. 2005 May 1;105(9):3465-71. Epub 2005 Jan 11.

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