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Items: 1 to 20 of 38

1.

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.

Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J.

J Immunol. 2008 Jul 15;181(2):1143-52.

2.

Developmental switch of intestinal antimicrobial peptide expression.

Ménard S, Förster V, Lotz M, Gütle D, Duerr CU, Gallo RL, Henriques-Normark B, Pütsep K, Andersson M, Glocker EO, Hornef MW.

J Exp Med. 2008 Jan 21;205(1):183-93. doi: 10.1084/jem.20071022. Epub 2008 Jan 7.

3.

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.

Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Núñez G, Inohara N.

EMBO J. 2008 Jan 23;27(2):373-83. Epub 2007 Dec 13.

4.

Signaling to NF-kappaB by Toll-like receptors.

Kawai T, Akira S.

Trends Mol Med. 2007 Nov;13(11):460-9. Epub 2007 Oct 29. Review.

PMID:
18029230
5.

TAK1 is a central mediator of NOD2 signaling in epidermal cells.

Kim JY, Omori E, Matsumoto K, Núñez G, Ninomiya-Tsuji J.

J Biol Chem. 2008 Jan 4;283(1):137-44. Epub 2007 Oct 26.

6.

Recognition of microorganisms and activation of the immune response.

Medzhitov R.

Nature. 2007 Oct 18;449(7164):819-26. Review.

PMID:
17943118
7.

Unravelling the pathogenesis of inflammatory bowel disease.

Xavier RJ, Podolsky DK.

Nature. 2007 Jul 26;448(7152):427-34. Review.

PMID:
17653185
9.

Epithelial NEMO links innate immunity to chronic intestinal inflammation.

Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M.

Nature. 2007 Mar 29;446(7135):557-61. Epub 2007 Mar 14.

10.

TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation.

Kajino T, Omori E, Ishii S, Matsumoto K, Ninomiya-Tsuji J.

J Biol Chem. 2007 Mar 30;282(13):9475-81. Epub 2007 Feb 2.

11.

Regulation of Nod1-mediated signaling pathways.

da Silva Correia J, Miranda Y, Leonard N, Hsu J, Ulevitch RJ.

Cell Death Differ. 2007 Apr;14(4):830-9. Epub 2006 Dec 22.

12.

Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

Fukata M, Chen A, Klepper A, Krishnareddy S, Vamadevan AS, Thomas LS, Xu R, Inoue H, Arditi M, Dannenberg AJ, Abreu MT.

Gastroenterology. 2006 Sep;131(3):862-77.

13.

TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.

Sato S, Sanjo H, Tsujimura T, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Takeuchi O, Akira S.

Int Immunol. 2006 Oct;18(10):1405-11. Epub 2006 Aug 28.

PMID:
16940043
14.

Essential role of TAK1 in thymocyte development and activation.

Liu HH, Xie M, Schneider MD, Chen ZJ.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82. Epub 2006 Jul 20.

15.

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

Wan YY, Chi H, Xie M, Schneider MD, Flavell RA.

Nat Immunol. 2006 Aug;7(8):851-8. Epub 2006 Jun 25.

PMID:
16799562
16.

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis.

Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J.

J Biol Chem. 2006 Jul 14;281(28):19610-7. Epub 2006 May 4.

17.

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells.

Lotz M, Gütle D, Walther S, Ménard S, Bogdan C, Hornef MW.

J Exp Med. 2006 Apr 17;203(4):973-84. Epub 2006 Apr 10.

18.

Ecological and evolutionary forces shaping microbial diversity in the human intestine.

Ley RE, Peterson DA, Gordon JI.

Cell. 2006 Feb 24;124(4):837-48. Review.

19.

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.

Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S.

Genes Dev. 2005 Nov 15;19(22):2668-81. Epub 2005 Oct 31.

20.

Essential function for the kinase TAK1 in innate and adaptive immune responses.

Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matsumoto K, Takeuchi O, Akira S.

Nat Immunol. 2005 Nov;6(11):1087-95. Epub 2005 Sep 25.

PMID:
16186825

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