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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

Dovey JS, Zacharek SJ, Kim CF, Lees JA.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11857-62. doi: 10.1073/pnas.0803574105.


Developmental alveolarization of the mouse lung.

Mund SI, Stampanoni M, Schittny JC.

Dev Dyn. 2008 Aug;237(8):2108-16. doi: 10.1002/dvdy.21633.


Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells.

Chen YC, Hsu HS, Chen YW, Tsai TH, How CK, Wang CY, Hung SC, Chang YL, Tsai ML, Lee YY, Ku HH, Chiou SH.

PLoS One. 2008 Jul 9;3(7):e2637. doi: 10.1371/journal.pone.0002637.


Cancer stem cells and the ontogeny of lung cancer.

Peacock CD, Watkins DN.

J Clin Oncol. 2008 Jun 10;26(17):2883-9. doi: 10.1200/JCO.2007.15.2702. Review.


A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, Morrisey EE.

Nat Genet. 2008 Jul;40(7):862-70. doi: 10.1038/ng.157.


Developmental biology: order in the lung.

Warburton D.

Nature. 2008 Jun 5;453(7196):733-5. doi: 10.1038/453733a. No abstract available.


Differences in gene expression levels between early and later stages of human lung development are opposite to those between normal lung tissue and non-small lung cell carcinoma.

Kopantzev EP, Monastyrskaya GS, Vinogradova TV, Zinovyeva MV, Kostina MB, Filyukova OB, Tonevitsky AG, Sukhikh GT, Sverdlov ED.

Lung Cancer. 2008 Oct;62(1):23-34. doi: 10.1016/j.lungcan.2008.02.011.


Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.

Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR, Jaenisch R, Sharp PA, Jacks T.

Cell. 2008 Mar 7;132(5):875-86. doi: 10.1016/j.cell.2008.02.019.


Suppression of non-small cell lung tumor development by the let-7 microRNA family.

Kumar MS, Erkeland SJ, Pester RE, Chen CY, Ebert MS, Sharp PA, Jacks T.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3903-8. doi: 10.1073/pnas.0712321105.


Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development.

Murry CE, Keller G.

Cell. 2008 Feb 22;132(4):661-80. doi: 10.1016/j.cell.2008.02.008. Review.


Hematopoiesis: an evolving paradigm for stem cell biology.

Orkin SH, Zon LI.

Cell. 2008 Feb 22;132(4):631-44. doi: 10.1016/j.cell.2008.01.025.


Cancer statistics, 2008.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ.

CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96. doi: 10.3322/CA.2007.0010.


Genetic similarities between organogenesis and tumorigenesis of the lung.

Powers S, Mu D.

Cell Cycle. 2008 Jan 15;7(2):200-4. Review.


Three-gene prognostic classifier for early-stage non small-cell lung cancer.

Lau SK, Boutros PC, Pintilie M, Blackhall FH, Zhu CQ, Strumpf D, Johnston MR, Darling G, Keshavjee S, Waddell TK, Liu N, Lau D, Penn LZ, Shepherd FA, Jurisica I, Der SD, Tsao MS.

J Clin Oncol. 2007 Dec 10;25(35):5562-9.


Identification and expansion of the tumorigenic lung cancer stem cell population.

Eramo A, Lotti F, Sette G, Pilozzi E, Biffoni M, Di Virgilio A, Conticello C, Ruco L, Peschle C, De Maria R.

Cell Death Differ. 2008 Mar;15(3):504-14.


Characterizing the cancer genome in lung adenocarcinoma.

Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, Broderick S, Chang AC, Chiang DY, Chirieac LR, Cho J, Fujii Y, Gazdar AF, Giordano T, Greulich H, Hanna M, Johnson BE, Kris MG, Lash A, Lin L, Lindeman N, Mardis ER, McPherson JD, Minna JD, Morgan MB, Nadel M, Orringer MB, Osborne JR, Ozenberger B, Ramos AH, Robinson J, Roth JA, Rusch V, Sasaki H, Shepherd F, Sougnez C, Spitz MR, Tsao MS, Twomey D, Verhaak RG, Weinstock GM, Wheeler DA, Winckler W, Yoshizawa A, Yu S, Zakowski MF, Zhang Q, Beer DG, Wistuba II, Watson MA, Garraway LA, Ladanyi M, Travis WD, Pao W, Rubin MA, Gabriel SB, Gibbs RA, Varmus HE, Wilson RK, Lander ES, Meyerson M.

Nature. 2007 Dec 6;450(7171):893-8.


Survival prediction of stage I lung adenocarcinomas by expression of 10 genes.

Bianchi F, Nuciforo P, Vecchi M, Bernard L, Tizzoni L, Marchetti A, Buttitta F, Felicioni L, Nicassio F, Di Fiore PP.

J Clin Invest. 2007 Nov;117(11):3436-44.


Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.

Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, Yajima N, Hamada K, Horie Y, Kubo H, Whitsett JA, Mak TW, Nakano T, Nakazato M, Suzuki A.

J Clin Invest. 2007 Oct;117(10):2929-40.


In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R.

Nature. 2007 Jul 19;448(7151):318-24.

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