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Items: 1 to 20 of 54

1.

Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor.

Weng SC, Kashida Y, Kulp SK, Wang D, Brueggemeier RW, Shapiro CL, Chen CS.

Mol Cancer Ther. 2008 Apr;7(4):800-8. doi: 10.1158/1535-7163.MCT-07-0434.

2.

The FoxO code.

Calnan DR, Brunet A.

Oncogene. 2008 Apr 7;27(16):2276-88. doi: 10.1038/onc.2008.21. Review.

PMID:
18391970
3.

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.

Cell Stem Cell. 2007 Jun 7;1(1):101-12. doi: 10.1016/j.stem.2007.02.001.

4.

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells.

Hui RC, Francis RE, Guest SK, Costa JR, Gomes AR, Myatt SS, Brosens JJ, Lam EW.

Mol Cancer Ther. 2008 Mar;7(3):670-8. doi: 10.1158/1535-7163.MCT-07-0397.

5.

Functional interaction between FOXO3a and ATM regulates DNA damage response.

Tsai WB, Chung YM, Takahashi Y, Xu Z, Hu MC.

Nat Cell Biol. 2008 Apr;10(4):460-7. doi: 10.1038/ncb1709. Epub 2008 Mar 16. Erratum in: Nat Cell Biol. 2009 Nov;11(11):1387.

6.

Epidermal growth factor receptor inhibitors in the treatment of lung cancer: reality and hopes.

Wheatley-Price P, Shepherd FA.

Curr Opin Oncol. 2008 Mar;20(2):162-75. doi: 10.1097/CCO.0b013e3282f335a3. Review.

PMID:
18300766
7.

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.

Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC.

Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Erratum in: Nat Cell Biol. 2008 Mar;10(3):370.

8.

The emerging roles of forkhead box (Fox) proteins in cancer.

Myatt SS, Lam EW.

Nat Rev Cancer. 2007 Nov;7(11):847-59. Review.

PMID:
17943136
9.

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification.

Tsai KL, Sun YJ, Huang CY, Yang JY, Hung MC, Hsiao CD.

Nucleic Acids Res. 2007;35(20):6984-94. Epub 2007 Oct 16.

10.

Biology of interactions: antiepidermal growth factor receptor agents.

Harari PM, Allen GW, Bonner JA.

J Clin Oncol. 2007 Sep 10;25(26):4057-65. Review.

PMID:
17827454
11.

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor.

Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A.

J Biol Chem. 2007 Oct 12;282(41):30107-19. Epub 2007 Aug 20.

13.

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.

Lee DF, Kuo HP, Chen CT, Hsu JM, Chou CK, Wei Y, Sun HL, Li LY, Ping B, Huang WC, He X, Hung JY, Lai CC, Ding Q, Su JL, Yang JY, Sahin AA, Hortobagyi GN, Tsai FJ, Tsai CH, Hung MC.

Cell. 2007 Aug 10;130(3):440-55.

14.

Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models.

Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC.

Cancer Cell. 2007 Jul;12(1):52-65.

15.

Phosphorylation of CK1delta: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo.

Giamas G, Hirner H, Shoshiashvili L, Grothey A, Gessert S, Kühl M, Henne-Bruns D, Vorgias CE, Knippschild U.

Biochem J. 2007 Sep 15;406(3):389-98.

16.

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG.

Cell. 2007 Jan 26;128(2):325-39.

17.

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA.

Cell. 2007 Jan 26;128(2):309-23.

18.

FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1.

Birkenkamp KU, Essafi A, van der Vos KE, da Costa M, Hui RC, Holstege F, Koenderman L, Lam EW, Coffer PJ.

J Biol Chem. 2007 Jan 26;282(4):2211-20. Epub 2006 Nov 27.

19.

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism.

Matsumoto M, Han S, Kitamura T, Accili D.

J Clin Invest. 2006 Sep;116(9):2464-72. Epub 2006 Aug 10.

20.

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