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Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.

Adams EL, Rice PJ, Graves B, Ensley HE, Yu H, Brown GD, Gordon S, Monteiro MA, Papp-Szabo E, Lowman DW, Power TD, Wempe MF, Williams DL.

J Pharmacol Exp Ther. 2008 Apr;325(1):115-23. doi: 10.1124/jpet.107.133124.


CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock.

Sarrias MR, Farnós M, Mota R, Sánchez-Barbero F, Ibáñez A, Gimferrer I, Vera J, Fenutría R, Casals C, Yélamos J, Lozano F.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11724-9.


Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain.

Rodamilans B, Muñoz IG, Bragado-Nilsson E, Sarrias MR, Padilla O, Blanco FJ, Lozano F, Montoya G.

J Biol Chem. 2007 Apr 27;282(17):12669-77.


Phenotypic and functional characterization of vaginal dendritic cells in a rat model of Candida albicans vaginitis.

De Bernardis F, Lucciarini R, Boccanera M, Amantini C, Arancia S, Morrone S, Mosca M, Cassone A, Santoni G.

Infect Immun. 2006 Jul;74(7):4282-94.


Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells.

Liu H, Komai-Koma M, Xu D, Liew FY.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7048-53.


Cutting edge: diminished T cell TLR expression and function modulates the immune response in human filarial infection.

Babu S, Blauvelt CP, Kumaraswami V, Nutman TB.

J Immunol. 2006 Apr 1;176(7):3885-9.


Toll-like receptor 2 controls expansion and function of regulatory T cells.

Sutmuller RP, den Brok MH, Kramer M, Bennink EJ, Toonen LW, Kullberg BJ, Joosten LA, Akira S, Netea MG, Adema GJ.

J Clin Invest. 2006 Feb;116(2):485-94.


Dectin-1: a signalling non-TLR pattern-recognition receptor.

Brown GD.

Nat Rev Immunol. 2006 Jan;6(1):33-43. Review.


Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

Caron G, Duluc D, Frémaux I, Jeannin P, David C, Gascan H, Delneste Y.

J Immunol. 2005 Aug 1;175(3):1551-7.


A role for human Sp alpha as a pattern recognition receptor.

Sarrias MR, Roselló S, Sánchez-Barbero F, Sierra JM, Vila J, Yélamos J, Vives J, Casals C, Lozano F.

J Biol Chem. 2005 Oct 21;280(42):35391-8.


The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells.

Willment JA, Marshall AS, Reid DM, Williams DL, Wong SY, Gordon S, Brown GD.

Eur J Immunol. 2005 May;35(5):1539-47.


Role of anti-beta-glucan antibody in host defense against fungi.

Ishibashi K, Yoshida M, Nakabayashi I, Shinohara H, Miura NN, Adachi Y, Ohno N.

FEMS Immunol Med Microbiol. 2005 Apr 1;44(1):99-109.


Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.

Bikker FJ, Ligtenberg AJ, End C, Renner M, Blaich S, Lyer S, Wittig R, van't Hof W, Veerman EC, Nazmi K, de Blieck-Hogervorst JM, Kioschis P, Nieuw Amerongen AV, Poustka A, Mollenhauer J.

J Biol Chem. 2004 Nov 12;279(46):47699-703.


Relevance of CD6-mediated interactions in T cell activation and proliferation.

Gimferrer I, Calvo M, Mittelbrunn M, Farnós M, Sarrias MR, Enrich C, Vives J, Sánchez-Madrid F, Lozano F.

J Immunol. 2004 Aug 15;173(4):2262-70.


Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice.

Genovese T, Di Paola R, Catalano P, Li JH, Xu W, Massuda E, Caputi AP, Zhang J, Cuzzocrea S.

Crit Care Med. 2004 Jun;32(6):1365-74.


Toll-like receptor ligands directly promote activated CD4+ T cell survival.

Gelman AE, Zhang J, Choi Y, Turka LA.

J Immunol. 2004 May 15;172(10):6065-73.


Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells.

Netea MG, Sutmuller R, Hermann C, Van der Graaf CA, Van der Meer JW, van Krieken JH, Hartung T, Adema G, Kullberg BJ.

J Immunol. 2004 Mar 15;172(6):3712-8.


The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system.

Sarrias MR, Grønlund J, Padilla O, Madsen J, Holmskov U, Lozano F.

Crit Rev Immunol. 2004;24(1):1-37. Review.


Antibody to soluble 1,3/1,6-beta-D-glucan, SCG in sera of naive DBA/2 mice.

Harada T, Nagi Miura N, Adachi Y, Nakajima M, Yadomae T, Ohno N.

Biol Pharm Bull. 2003 Aug;26(8):1225-8.

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