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Items: 13

1.

Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.

Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B.

Bioorg Med Chem Lett. 2008 Nov 15;18(22):5951-4. doi: 10.1016/j.bmcl.2008.07.072. Epub 2008 Jul 24.

2.

New lactimidomycin congeners shed insight into lactimidomycin biosynthesis in Streptomyces amphibiosporus.

Ju J, Seo JW, Her Y, Lim SK, Shen B.

Org Lett. 2007 Dec 6;9(25):5183-6. Epub 2007 Nov 13.

PMID:
17997563
3.

Total synthesis of (+)-isomigrastatin.

Krauss IJ, Mandal M, Danishefsky SJ.

Angew Chem Int Ed Engl. 2007;46(29):5576-9. No abstract available.

PMID:
17583888
4.

Chemistry and biology in search of antimetastatic agents.

PĂ©rez L, Danishefsky SJ.

ACS Chem Biol. 2007 Mar 20;2(3):159-62. Review.

PMID:
17373763
7.

Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.

Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang XY.

Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3772-6. Epub 2005 Feb 22.

8.

Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin.

Ju J, Lim SK, Jiang H, Shen B.

J Am Chem Soc. 2005 Feb 16;127(6):1622-3.

PMID:
15700980
9.

The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis.

Gaul C, Njardarson JT, Shan D, Dorn DC, Wu KD, Tong WP, Huang XY, Moore MA, Danishefsky SJ.

J Am Chem Soc. 2004 Sep 15;126(36):11326-37.

PMID:
15355116
10.

Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin.

Njardarson JT, Gaul C, Shan D, Huang XY, Danishefsky SJ.

J Am Chem Soc. 2004 Feb 4;126(4):1038-40.

PMID:
14746469
11.

Migrastatin and a new compound, isomigrastatin, from Streptomyces platensis.

Woo EJ, Starks CM, Carney JR, Arslanian R, Cadapan L, Zavala S, Licari P.

J Antibiot (Tokyo). 2002 Feb;55(2):141-6.

12.

Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities.

Nakae K, Yoshimoto Y, Sawa T, Homma Y, Hamada M, Takeuchi T, Imoto M.

J Antibiot (Tokyo). 2000 Oct;53(10):1130-6.

13.

Lactimidomycin, a new glutarimide group antibiotic. Production, isolation, structure and biological activity.

Sugawara K, Nishiyama Y, Toda S, Komiyama N, Hatori M, Moriyama T, Sawada Y, Kamei H, Konishi M, Oki T.

J Antibiot (Tokyo). 1992 Sep;45(9):1433-41.

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