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Items: 1 to 20 of 39

1.

Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts.

Filipp D, Moemeni B, Ferzoco A, Kathirkamathamby K, Zhang J, Ballek O, Davidson D, Veillette A, Julius M.

J Biol Chem. 2008 Sep 26;283(39):26409-22. doi: 10.1074/jbc.M710372200. Epub 2008 Jul 27.

2.

Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.

Zhu JW, Brdicka T, Katsumoto TR, Lin J, Weiss A.

Immunity. 2008 Feb;28(2):183-96. doi: 10.1016/j.immuni.2007.11.024. Epub 2008 Jan 31.

3.

The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.

McNeill L, Salmond RJ, Cooper JC, Carret CK, Cassady-Cain RL, Roche-Molina M, Tandon P, Holmes N, Alexander DR.

Immunity. 2007 Sep;27(3):425-37. Epub 2007 Aug 23.

5.

PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes.

Davidson D, Schraven B, Veillette A.

Mol Cell Biol. 2007 Mar;27(5):1960-73. Epub 2007 Jan 8.

6.

Lck regulates the threshold of activation in primary T cells, while both Lck and Fyn contribute to the magnitude of the extracellular signal-related kinase response.

Lovatt M, Filby A, Parravicini V, Werlen G, Palmer E, Zamoyska R.

Mol Cell Biol. 2006 Nov;26(22):8655-65. Epub 2006 Sep 11.

7.

Strength of signal: a fundamental mechanism for cell fate specification.

Hayes SM, Love PE.

Immunol Rev. 2006 Feb;209:170-5. Review.

PMID:
16448542
8.

Altered CD45 expression and disease.

Tchilian EZ, Beverley PC.

Trends Immunol. 2006 Mar;27(3):146-53. Epub 2006 Jan 18. Review.

PMID:
16423560
9.

CD45: all is not yet crystal clear.

Holmes N.

Immunology. 2006 Feb;117(2):145-55. Review.

10.

The juxtamembrane wedge negatively regulates CD45 function in B cells.

Hermiston ML, Tan AL, Gupta VA, Majeti R, Weiss A.

Immunity. 2005 Dec;23(6):635-47.

11.

Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.

Nam HJ, Poy F, Saito H, Frederick CA.

J Exp Med. 2005 Feb 7;201(3):441-52. Epub 2005 Jan 31. Erratum in: J Exp Med. 2005 Mar 21;201(6):1019.

12.

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.

Palacios EH, Weiss A.

Oncogene. 2004 Oct 18;23(48):7990-8000. Review.

PMID:
15489916
13.

TCR affinity and negative regulation limit autoimmunity.

Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS.

Nat Med. 2004 Nov;10(11):1234-9. Epub 2004 Oct 3.

14.

H2O2-induced intermolecular disulfide bond formation between receptor protein-tyrosine phosphatases.

van der Wijk T, Overvoorde J, den Hertog J.

J Biol Chem. 2004 Oct 22;279(43):44355-61. Epub 2004 Aug 4.

15.

Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus.

Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA.

J Clin Invest. 2004 Apr;113(8):1176-87.

16.

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice.

Sakaguchi N, Takahashi T, Hata H, Nomura T, Tagami T, Yamazaki S, Sakihama T, Matsutani T, Negishi I, Nakatsuru S, Sakaguchi S.

Nature. 2003 Nov 27;426(6965):454-60.

17.

Surface T-cell antigen receptor expression and availability for long-term antigenic signaling.

Schrum AG, Turka LA, Palmer E.

Immunol Rev. 2003 Dec;196:7-24. Review.

PMID:
14617194
18.

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation.

Zamoyska R, Basson A, Filby A, Legname G, Lovatt M, Seddon B.

Immunol Rev. 2003 Feb;191:107-18. Review.

PMID:
12614355
19.
20.

CD45: a critical regulator of signaling thresholds in immune cells.

Hermiston ML, Xu Z, Weiss A.

Annu Rev Immunol. 2003;21:107-37. Epub 2001 Dec 19. Review.

PMID:
12414720

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