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Items: 1 to 20 of 49

1.

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo.

Zabolotny JM, Kim YB, Welsh LA, Kershaw EE, Neel BG, Kahn BB.

J Biol Chem. 2008 May 23;283(21):14230-41. doi: 10.1074/jbc.M800061200. Epub 2008 Feb 14.

2.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR.

Cell Metab. 2008 Feb;7(2):125-34. doi: 10.1016/j.cmet.2007.11.013.

3.

Selective versus total insulin resistance: a pathogenic paradox.

Brown MS, Goldstein JL.

Cell Metab. 2008 Feb;7(2):95-6. doi: 10.1016/j.cmet.2007.12.009. Review.

4.

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

Delibegovic M, Bence KK, Mody N, Hong EG, Ko HJ, Kim JK, Kahn BB, Neel BG.

Mol Cell Biol. 2007 Nov;27(21):7727-34. Epub 2007 Aug 27.

5.

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease.

Gregor MF, Hotamisligil GS.

J Lipid Res. 2007 Sep;48(9):1905-14. Epub 2007 May 9. Review.

6.

Signal integration in the endoplasmic reticulum unfolded protein response.

Ron D, Walter P.

Nat Rev Mol Cell Biol. 2007 Jul;8(7):519-29. Review.

PMID:
17565364
7.

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.

Cohen SE, Kokkotou E, Biddinger SB, Kondo T, Gebhardt R, Kratzsch J, Mantzoros CS, Kahn CR.

J Biol Chem. 2007 Aug 10;282(32):23672-8. Epub 2007 Jun 7.

8.

Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis.

Marí M, Caballero F, Colell A, Morales A, Caballeria J, Fernandez A, Enrich C, Fernandez-Checa JC, García-Ruiz C.

Cell Metab. 2006 Sep;4(3):185-98.

9.
10.

Neuronal PTP1B regulates body weight, adiposity and leptin action.

Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB.

Nat Med. 2006 Aug;12(8):917-24. Epub 2006 Jul 16. Erratum in: Nat Med. 2010 Feb;16(2):237.

PMID:
16845389
11.

ER stress: can the liver cope?

Ji C, Kaplowitz N.

J Hepatol. 2006 Aug;45(2):321-33. Epub 2006 Jun 15. Review.

PMID:
16797772
12.

Critical nodes in signalling pathways: insights into insulin action.

Taniguchi CM, Emanuelli B, Kahn CR.

Nat Rev Mol Cell Biol. 2006 Feb;7(2):85-96. Review.

PMID:
16493415
13.

From mice to men: insights into the insulin resistance syndromes.

Biddinger SB, Kahn CR.

Annu Rev Physiol. 2006;68:123-58. Review.

PMID:
16460269
14.

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.

Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.

FASEB J. 2005 Dec;19(14):2072-4. Epub 2005 Oct 3. Retraction in: FASEB J. 2009 Aug;23(8):2790.

PMID:
16203862
15.

Adipokines: therapeutic targets for metabolic syndrome.

Kobayashi K.

Curr Drug Targets. 2005 Jun;6(4):525-9. Review.

PMID:
16026271
16.

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis.

Lam TK, Pocai A, Gutierrez-Juarez R, Obici S, Bryan J, Aguilar-Bryan L, Schwartz GJ, Rossetti L.

Nat Med. 2005 Mar;11(3):320-7. Epub 2005 Feb 27.

PMID:
15735652
17.

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism.

Taniguchi CM, Ueki K, Kahn R.

J Clin Invest. 2005 Mar;115(3):718-27. Erratum in: J Clin Invest. 2005 May;115(5):1388.

18.

Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice.

Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG.

J Biol Chem. 2005 Apr 15;280(15):15038-46. Epub 2005 Feb 7.

19.

ER stress and the unfolded protein response.

Schröder M, Kaufman RJ.

Mutat Res. 2005 Jan 6;569(1-2):29-63. Review.

PMID:
15603751
20.

Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity.

Pei Z, Liu G, Lubben TH, Szczepankiewicz BG.

Curr Pharm Des. 2004;10(28):3481-504. Review.

PMID:
15579047

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