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Items: 1 to 20 of 40

1.

Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.

Warrington NM, Woerner BM, Daginakatte GC, Dasgupta B, Perry A, Gutmann DH, Rubin JB.

Cancer Res. 2007 Sep 15;67(18):8588-95.

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Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.

Yang L, Jackson E, Woerner BM, Perry A, Piwnica-Worms D, Rubin JB.

Cancer Res. 2007 Jan 15;67(2):651-8.

4.

Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling.

Lynch MJ, Hill EV, Houslay MD.

Curr Top Dev Biol. 2006;75:225-59. Review.

PMID:
16984814
5.

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use.

Bender AT, Beavo JA.

Pharmacol Rev. 2006 Sep;58(3):488-520. Review.

6.

Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+.

Huston E, Gall I, Houslay TM, Houslay MD.

J Cell Sci. 2006 Sep 15;119(Pt 18):3799-810. Epub 2006 Aug 29.

7.

Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.

Chakravarti A, Erkkinen MG, Nestler U, Stupp R, Mehta M, Aldape K, Gilbert MR, Black PM, Loeffler JS.

Clin Cancer Res. 2006 Aug 1;12(15):4738-46.

9.

Malignant gliomas: strategies to increase the effectiveness of targeted molecular treatment.

Wen PY, Kesari S, Drappatz J.

Expert Rev Anticancer Ther. 2006 May;6(5):733-54. Review.

PMID:
16759164
10.

Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.

Su X, Gopalakrishnan V, Stearns D, Aldape K, Lang FF, Fuller G, Snyder E, Eberhart CG, Majumder S.

Mol Cell Biol. 2006 Mar;26(5):1666-78.

11.

Widespread CXCR4 activation in astrocytomas revealed by phospho-CXCR4-specific antibodies.

Woerner BM, Warrington NM, Kung AL, Perry A, Rubin JB.

Cancer Res. 2005 Dec 15;65(24):11392-9.

12.

Keynote review: phosphodiesterase-4 as a therapeutic target.

Houslay MD, Schafer P, Zhang KY.

Drug Discov Today. 2005 Nov 15;10(22):1503-19. Review.

PMID:
16257373
14.

Real-time imaging of ligand-induced IKK activation in intact cells and in living mice.

Gross S, Piwnica-Worms D.

Nat Methods. 2005 Aug;2(8):607-14.

PMID:
16094386
15.

Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.

Jin SL, Lan L, Zoudilova M, Conti M.

J Immunol. 2005 Aug 1;175(3):1523-31.

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Chemotherapy for brain tumors--a new beginning.

DeAngelis LM.

N Engl J Med. 2005 Mar 10;352(10):1036-8. No abstract available.

PMID:
15758016
19.

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R.

N Engl J Med. 2005 Mar 10;352(10):997-1003.

20.

CXCR4 regulates growth of both primary and metastatic breast cancer.

Smith MC, Luker KE, Garbow JR, Prior JL, Jackson E, Piwnica-Worms D, Luker GD.

Cancer Res. 2004 Dec 1;64(23):8604-12.

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