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Items: 1 to 20 of 58

1.

Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.

Stracker TH, Couto SS, Cordon-Cardo C, Matos T, Petrini JH.

Mol Cell. 2008 Jul 11;31(1):21-32. doi: 10.1016/j.molcel.2008.04.028. Erratum in: Mol Cell. 2008 Dec 26;32(6):889.

2.

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.

Lee JH, Paull TT.

Oncogene. 2007 Dec 10;26(56):7741-8. Review.

PMID:
18066086
3.

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.

4.

Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis.

Difilippantonio S, Celeste A, Kruhlak MJ, Lee Y, Difilippantonio MJ, Feigenbaum L, Jackson SP, McKinnon PJ, Nussenzweig A.

J Exp Med. 2007 May 14;204(5):1003-11.

5.

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.

Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH.

Nature. 2007 May 10;447(7141):218-21.

6.

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks.

Yang YG, Saidi A, Frappart PO, Min W, Barrucand C, Dumon-Jones V, Michelon J, Herceg Z, Wang ZQ.

EMBO J. 2006 Nov 29;25(23):5527-38.

7.

DNA-PK autophosphorylation facilitates Artemis endonuclease activity.

Goodarzi AA, Yu Y, Riballo E, Douglas P, Walker SA, Ye R, Härer C, Marchetti C, Morrice N, Jeggo PA, Lees-Miller SP.

EMBO J. 2006 Aug 23;25(16):3880-9.

8.

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination.

Celli GB, Denchi EL, de Lange T.

Nat Cell Biol. 2006 Aug;8(8):885-90.

PMID:
16845382
9.
10.

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.

Gladdy RA, Nutter LM, Kunath T, Danska JS, Guidos CJ.

Mol Cancer Res. 2006 May;4(5):311-8.

11.

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.

Di Virgilio M, Gautier J.

J Cell Biol. 2005 Dec 5;171(5):765-71.

12.

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

You Z, Chahwan C, Bailis J, Hunter T, Russell P.

Mol Cell Biol. 2005 Jul;25(13):5363-79.

13.

The Rad50 hook domain is a critical determinant of Mre11 complex functions.

Wiltzius JJ, Hohl M, Fleming JC, Petrini JH.

Nat Struct Mol Biol. 2005 May;12(5):403-7.

PMID:
15852023
14.

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.

Falck J, Coates J, Jackson SP.

Nature. 2005 Mar 31;434(7033):605-11.

PMID:
15758953
15.

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development.

Rooney S, Alt FW, Sekiguchi J, Manis JP.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2471-5.

16.

Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

Chen BP, Chan DW, Kobayashi J, Burma S, Asaithamby A, Morotomi-Yano K, Botvinick E, Qin J, Chen DJ.

J Biol Chem. 2005 Apr 15;280(15):14709-15.

17.

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

Riballo E, Kühne M, Rief N, Doherty A, Smith GC, Recio MJ, Reis C, Dahm K, Fricke A, Krempler A, Parker AR, Jackson SP, Gennery A, Jeggo PA, Löbrich M.

Mol Cell. 2004 Dec 3;16(5):715-24.

18.

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together.

Stracker TH, Theunissen JW, Morales M, Petrini JH.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):845-54. Review.

PMID:
15279769
19.

Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells.

Couëdel C, Mills KD, Barchi M, Shen L, Olshen A, Johnson RD, Nussenzweig A, Essers J, Kanaar R, Li GC, Alt FW, Jasin M.

Genes Dev. 2004 Jun 1;18(11):1293-304.

20.

Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability.

Mills KD, Ferguson DO, Essers J, Eckersdorff M, Kanaar R, Alt FW.

Genes Dev. 2004 Jun 1;18(11):1283-92.

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