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Items: 1 to 20 of 36

1.

WNK2 modulates MEK1 activity through the Rho GTPase pathway.

Moniz S, Matos P, Jordan P.

Cell Signal. 2008 Oct;20(10):1762-8. doi: 10.1016/j.cellsig.2008.06.002. Epub 2008 Jun 14.

PMID:
18593598
2.

Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations.

Smiraglia DJ, Kazhiyur-Mannar R, Oakes CC, Wu YZ, Liang P, Ansari T, Su J, Rush LJ, Smith LT, Yu L, Liu C, Dai Z, Chen SS, Wang SH, Costello J, Ioshikhes I, Dawson DW, Hong JS, Teitell MA, Szafranek A, Camoriano M, Song F, Elliott R, Held W, Trasler JM, Plass C, Wenger R.

BMC Genomics. 2007 Nov 30;8:446.

3.

Malignant transformation-related genes in meningiomas: allelic loss on 1p36 and methylation status of p73 and RASSF1A.

Nakane Y, Natsume A, Wakabayashi T, Oi S, Ito M, Inao S, Saito K, Yoshida J.

J Neurosurg. 2007 Aug;107(2):398-404.

PMID:
17695396
4.

Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2.

Moniz S, Veríssimo F, Matos P, Brazão R, Silva E, Kotelevets L, Chastre E, Gespach C, Jordan P.

Oncogene. 2007 Sep 6;26(41):6071-81. Epub 2007 Jul 30. Erratum in: Oncogene. 2008 Jan 3;27(1):155. Kotevelets, L [corrected to Kotelevets, L].

PMID:
17667937
5.

Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth.

Hong C, Moorefield KS, Jun P, Aldape KD, Kharbanda S, Phillips HS, Costello JF.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10974-9. Epub 2007 Jun 19.

6.

Association between absence of epidermal growth factor receptor immunoreactivity and poor prognosis in patients with atypical meningioma.

Smith JS, Lal A, Harmon-Smith M, Bollen AW, McDermott MW.

J Neurosurg. 2007 Jun;106(6):1034-40.

PMID:
17564176
7.

Patterns of somatic mutation in human cancer genomes.

Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR.

Nature. 2007 Mar 8;446(7132):153-8.

8.

Comprehensive genetic and epigenetic analysis of sporadic meningioma for macro-mutations on 22q and micro-mutations within the NF2 locus.

Hansson CM, Buckley PG, Grigelioniene G, Piotrowski A, Hellström AR, Mantripragada K, Jarbo C, Mathiesen T, Dumanski JP.

BMC Genomics. 2007 Jan 12;8:16.

9.

The consensus coding sequences of human breast and colorectal cancers.

Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7.

10.

Large-scale structure of genomic methylation patterns.

Rollins RA, Haghighi F, Edwards JR, Das R, Zhang MQ, Ju J, Bestor TH.

Genome Res. 2006 Feb;16(2):157-63. Epub 2005 Dec 19.

11.

Somatic mutations of the protein kinase gene family in human lung cancer.

Davies H, Hunter C, Smith R, Stephens P, Greenman C, Bignell G, Teague J, Butler A, Edkins S, Stevens C, Parker A, O'Meara S, Avis T, Barthorpe S, Brackenbury L, Buck G, Clements J, Cole J, Dicks E, Edwards K, Forbes S, Gorton M, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Kosmidou V, Laman R, Lugg R, Menzies A, Perry J, Petty R, Raine K, Shepherd R, Small A, Solomon H, Stephens Y, Tofts C, Varian J, Webb A, West S, Widaa S, Yates A, Brasseur F, Cooper CS, Flanagan AM, Green A, Knowles M, Leung SY, Looijenga LH, Malkowicz B, Pierotti MA, Teh BT, Yuen ST, Lakhani SR, Easton DF, Weber BL, Goldstraw P, Nicholson AG, Wooster R, Stratton MR, Futreal PA.

Cancer Res. 2005 Sep 1;65(17):7591-5.

12.

Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma.

Lusis EA, Watson MA, Chicoine MR, Lyman M, Roerig P, Reifenberger G, Gutmann DH, Perry A.

Cancer Res. 2005 Aug 15;65(16):7121-6.

13.

WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism.

Xu BE, Stippec S, Lazrak A, Huang CL, Cobb MH.

J Biol Chem. 2005 Oct 7;280(40):34218-23. Epub 2005 Aug 4.

14.

Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas.

Liu Y, Pang JC, Dong S, Mao B, Poon WS, Ng HK.

Hum Pathol. 2005 Apr;36(4):416-25.

PMID:
15892004
15.

Properties of WNK1 and implications for other family members.

Lenertz LY, Lee BH, Min X, Xu BE, Wedin K, Earnest S, Goldsmith EJ, Cobb MH.

J Biol Chem. 2005 Jul 22;280(29):26653-8. Epub 2005 May 9.

16.

Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport.

Yang CL, Zhu X, Wang Z, Subramanya AR, Ellison DH.

J Clin Invest. 2005 May;115(5):1379-87. Epub 2005 Apr 7.

17.

Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.

Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP.

J Biol Chem. 2005 Jun 3;280(22):21622-8. Epub 2005 Mar 30.

18.

DNA methylation of multiple promoter-associated CpG islands in meningiomas: relationship with the allelic status at 1p and 22q.

Bello MJ, Amiñoso C, Lopez-Marin I, Arjona D, Gonzalez-Gomez P, Alonso ME, Lomas J, de Campos JM, Kusak ME, Vaquero J, Isla A, Gutierrez M, Sarasa JL, Rey JA.

Acta Neuropathol. 2004 Nov;108(5):413-21. Epub 2004 Sep 10.

PMID:
15365725
19.

Meningiomas.

Whittle IR, Smith C, Navoo P, Collie D.

Lancet. 2004 May 8;363(9420):1535-43. Review.

PMID:
15135603
20.

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