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Items: 1 to 20 of 74

1.

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families.

Erlich H, Valdes AM, Noble J, Carlson JA, Varney M, Concannon P, Mychaleckyj JC, Todd JA, Bonella P, Fear AL, Lavant E, Louey A, Moonsamy P; Type 1 Diabetes Genetics Consortium..

Diabetes. 2008 Apr;57(4):1084-92. doi: 10.2337/db07-1331. Epub 2008 Feb 5.

2.

Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production.

Jain R, Tartar DM, Gregg RK, Divekar RD, Bell JJ, Lee HH, Yu P, Ellis JS, Hoeman CM, Franklin CL, Zaghouani H.

J Exp Med. 2008 Jan 21;205(1):207-18. doi: 10.1084/jem.20071878. Epub 2008 Jan 14.

3.

Th17 cells: a new fate for differentiating helper T cells.

Chen Z, O'Shea JJ.

Immunol Res. 2008;41(2):87-102. doi: 10.1007/s12026-007-8014-9. Review.

PMID:
18172584
4.

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.

Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J, Hulme J, Maier LM, Smyth D, Bailey R, Cooper JD, Ribas G, Campbell RD, Clayton DG, Todd JA; Wellcome Trust Case Control Consortium..

Nature. 2007 Dec 6;450(7171):887-92. Epub 2007 Nov 14.

5.

Danger-free autoimmune disease in Aire-deficient mice.

Gray DH, Gavanescu I, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18193-8. Epub 2007 Nov 8.

6.

Type 1 diabetes as a relapsing-remitting disease?

von Herrath M, Sanda S, Herold K.

Nat Rev Immunol. 2007 Dec;7(12):988-94. Review.

PMID:
17982429
7.

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.

Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, Gottlieb P, Rewers M, Eisenbarth GS, Jensen J, Davidson HW, Hutton JC.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17040-5. Epub 2007 Oct 17.

8.

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C; Genetics of Type 1 Diabetes in Finland., Simmonds MJ, Heward JM, Gough SC; Wellcome Trust Case Control Consortium., Dunger DB, Wicker LS, Clayton DG.

Nat Genet. 2007 Jul;39(7):857-64. Epub 2007 Jun 6.

9.
10.

The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form.

Levisetti MG, Suri A, Petzold SJ, Unanue ER.

J Immunol. 2007 May 15;178(10):6051-7.

11.

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.

Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS; Wellcome Trust Case Control Consortium (WTCCC)., McCarthy MI, Hattersley AT.

Science. 2007 Jun 1;316(5829):1336-41. Epub 2007 Apr 26. Erratum in: Science. 2007 Aug 24;317(5841):1035-6.

12.

Modeling the mechanisms of acute hepatitis B virus infection.

Ciupe SM, Ribeiro RM, Nelson PW, Perelson AS.

J Theor Biol. 2007 Jul 7;247(1):23-35. Epub 2007 Mar 12.

13.

Generation of T-cell receptor retrogenic mice.

Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA.

Nat Protoc. 2006;1(1):406-17.

PMID:
17406263
14.

Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells.

Davidson TS, DiPaolo RJ, Andersson J, Shevach EM.

J Immunol. 2007 Apr 1;178(7):4022-6.

15.

Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.

Gavanescu I, Kessler B, Ploegh H, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4583-7. Epub 2007 Mar 6.

16.

Ito cells are liver-resident antigen-presenting cells for activating T cell responses.

Winau F, Hegasy G, Weiskirchen R, Weber S, Cassan C, Sieling PA, Modlin RL, Liblau RS, Gressner AM, Kaufmann SH.

Immunity. 2007 Jan;26(1):117-29.

17.

TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.

Zipris D, Lien E, Nair A, Xie JX, Greiner DL, Mordes JP, Rossini AA.

J Immunol. 2007 Jan 15;178(2):693-701.

18.

Altered natural killer cells in type 1 diabetic patients.

Rodacki M, Svoren B, Butty V, Besse W, Laffel L, Benoist C, Mathis D.

Diabetes. 2007 Jan;56(1):177-85.

19.

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW.

J Clin Invest. 2006 Dec;116(12):3258-65.

20.

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR.

Cell. 2006 Sep 22;126(6):1121-33.

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