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Kinetic flux profiling for quantitation of cellular metabolic fluxes.

Yuan J, Bennett BD, Rabinowitz JD.

Nat Protoc. 2008;3(8):1328-40. doi: 10.1038/nprot.2008.131.


Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach.

Bennett BD, Yuan J, Kimball EH, Rabinowitz JD.

Nat Protoc. 2008;3(8):1299-311. doi: 10.1038/nprot.2008.107.


Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques.

Wikoff WR, Pendyala G, Siuzdak G, Fox HS.

J Clin Invest. 2008 Jul;118(7):2661-9. doi: 10.1172/JCI34138.


Novel inhibitors of human CMV.

Andrei G, De Clercq E, Snoeck R.

Curr Opin Investig Drugs. 2008 Feb;9(2):132-45. Review.


Identification of host proteins required for HIV infection through a functional genomic screen.

Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.

Science. 2008 Feb 15;319(5865):921-6. doi: 10.1126/science.1152725. Epub 2008 Jan 10.


Metabolomics identifies perturbations in human disorders of propionate metabolism.

Wikoff WR, Gangoiti JA, Barshop BA, Siuzdak G.

Clin Chem. 2007 Dec;53(12):2169-76. Epub 2007 Oct 19.


Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals.

Rezzi S, Ramadan Z, Martin FP, Fay LB, van Bladeren P, Lindon JC, Nicholson JK, Kochhar S.

J Proteome Res. 2007 Nov;6(11):4469-77. Epub 2007 Oct 12.


Multiple high-throughput analyses monitor the response of E. coli to perturbations.

Ishii N, Nakahigashi K, Baba T, Robert M, Soga T, Kanai A, Hirasawa T, Naba M, Hirai K, Hoque A, Ho PY, Kakazu Y, Sugawara K, Igarashi S, Harada S, Masuda T, Sugiyama N, Togashi T, Hasegawa M, Takai Y, Yugi K, Arakawa K, Iwata N, Toya Y, Nakayama Y, Nishioka T, Shimizu K, Mori H, Tomita M.

Science. 2007 Apr 27;316(5824):593-7. Epub 2007 Mar 22.


A comprehensive urinary metabolomic approach for identifying kidney cancerr.

Kind T, Tolstikov V, Fiehn O, Weiss RH.

Anal Biochem. 2007 Apr 15;363(2):185-95. Epub 2007 Jan 26.


Global reconstruction of the human metabolic network based on genomic and bibliomic data.

Duarte NC, Becker SA, Jamshidi N, Thiele I, Mo ML, Vo TD, Srivas R, Palsson BØ.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1777-82. Epub 2007 Jan 31.


Dynamics of the cellular metabolome during human cytomegalovirus infection.

Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD.

PLoS Pathog. 2006 Dec;2(12):e132.


Metabolic networks in motion: 13C-based flux analysis.

Sauer U.

Mol Syst Biol. 2006;2:62. Epub 2006 Nov 14. Review.


Acetyl-coenzyme A carboxylases: versatile targets for drug discovery.

Tong L, Harwood HJ Jr.

J Cell Biochem. 2006 Dec 15;99(6):1476-88. Review.


Human cytomegalovirus-induced reduction of extracellular matrix proteins in vascular smooth muscle cell cultures: a pathomechanism in vasculopathies?

Reinhardt B, Winkler M, Schaarschmidt P, Pretsch R, Zhou S, Vaida B, Schmid-Kotsas A, Michel D, Walther P, Bachem M, Mertens T.

J Gen Virol. 2006 Oct;87(Pt 10):2849-58.


Kinetic flux profiling of nitrogen assimilation in Escherichia coli.

Yuan J, Fowler WU, Kimball E, Lu W, Rabinowitz JD.

Nat Chem Biol. 2006 Oct;2(10):529-30. Epub 2006 Aug 27.


Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia.

Holmes E, Tsang TM, Huang JT, Leweke FM, Koethe D, Gerth CW, Nolden BM, Gross S, Schreiber D, Nicholson JK, Bahn S.

PLoS Med. 2006 Aug;3(8):e327.


Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

Bajad SU, Lu W, Kimball EH, Yuan J, Peterson C, Rabinowitz JD.

J Chromatogr A. 2006 Aug 25;1125(1):76-88. Epub 2006 Jun 6.


Metabolomic identification of novel biomarkers of myocardial ischemia.

Sabatine MS, Liu E, Morrow DA, Heller E, McCarroll R, Wiegand R, Berriz GF, Roth FP, Gerszten RE.

Circulation. 2005 Dec 20;112(25):3868-75. Epub 2005 Dec 12.

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