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Items: 1 to 20 of 26

1.

The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.

Rao A, Haywood J, Craddock AL, Belinsky MG, Kruh GD, Dawson PA.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3891-6. doi: 10.1073/pnas.0712328105. Epub 2008 Feb 21.

2.

Co-receptor requirements for fibroblast growth factor-19 signaling.

Wu X, Ge H, Gupte J, Weiszmann J, Shimamoto G, Stevens J, Hawkins N, Lemon B, Shen W, Xu J, Veniant MM, Li YS, Lindberg R, Chen JL, Tian H, Li Y.

J Biol Chem. 2007 Oct 5;282(40):29069-72. Epub 2007 Aug 21.

3.

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, Eliseenkova AV, Mohammadi M, Rosenblatt KP, Kliewer SA, Kuro-o M.

J Biol Chem. 2007 Sep 14;282(37):26687-95. Epub 2007 Jul 10.

4.

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig.

Radhakrishnan A, Ikeda Y, Kwon HJ, Brown MS, Goldstein JL.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6511-8. Epub 2007 Apr 11.

5.

Biliary secretion and excretion in health and disease: current concepts.

Hofmann AF.

Ann Hepatol. 2007 Jan-Mar;6(1):15-27. Review.

PMID:
17297425
6.

Identification of a hormonal basis for gallbladder filling.

Choi M, Moschetta A, Bookout AL, Peng L, Umetani M, Holmstrom SR, Suino-Powell K, Xu HE, Richardson JA, Gerard RD, Mangelsdorf DJ, Kliewer SA.

Nat Med. 2006 Nov;12(11):1253-5. Epub 2006 Oct 29.

PMID:
17072310
7.

Hepatobiliary transporters and drug-induced cholestasis.

Pauli-Magnus C, Meier PJ.

Hepatology. 2006 Oct;44(4):778-87. Review.

PMID:
17006912
8.

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.

Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC, Auwerx J.

Nature. 2006 Jan 26;439(7075):484-9. Epub 2006 Jan 8.

PMID:
16400329
9.

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA.

Cell Metab. 2005 Oct;2(4):217-25.

10.

Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho.

Ito S, Fujimori T, Furuya A, Satoh J, Nabeshima Y, Nabeshima Y.

J Clin Invest. 2005 Aug;115(8):2202-8.

11.

The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.

Dawson PA, Hubbert M, Haywood J, Craddock AL, Zerangue N, Christian WV, Ballatori N.

J Biol Chem. 2005 Feb 25;280(8):6960-8. Epub 2004 Nov 24.

12.

Enzymes involved in the activation and inactivation of vitamin D.

Prosser DE, Jones G.

Trends Biochem Sci. 2004 Dec;29(12):664-73. Review.

PMID:
15544953
13.

Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase.

Cheng JB, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7711-5. Epub 2004 May 5.

14.

De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase.

Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW.

J Biol Chem. 2003 Sep 26;278(39):38084-93. Epub 2003 Jul 16.

15.

Liver X receptor signaling pathways in cardiovascular disease.

Tontonoz P, Mangelsdorf DJ.

Mol Endocrinol. 2003 Jun;17(6):985-93. Epub 2003 Apr 10. Review.

PMID:
12690094
16.

The enzymes, regulation, and genetics of bile acid synthesis.

Russell DW.

Annu Rev Biochem. 2003;72:137-74. Epub 2003 Jan 16. Review.

PMID:
12543708
17.

A G protein-coupled receptor responsive to bile acids.

Kawamata Y, Fujii R, Hosoya M, Harada M, Yoshida H, Miwa M, Fukusumi S, Habata Y, Itoh T, Shintani Y, Hinuma S, Fujisawa Y, Fujino M.

J Biol Chem. 2003 Mar 14;278(11):9435-40. Epub 2003 Jan 10.

18.

Identification of membrane-type receptor for bile acids (M-BAR).

Maruyama T, Miyamoto Y, Nakamura T, Tamai Y, Okada H, Sugiyama E, Nakamura T, Itadani H, Tanaka K.

Biochem Biophys Res Commun. 2002 Nov 15;298(5):714-9.

PMID:
12419312
19.

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.

Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL.

J Biol Chem. 2000 May 19;275(20):15482-9.

20.

Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin.

Babiker A, Andersson O, Lindblom D, van der Linden J, Wiklund B, Lütjohann D, Diczfalusy U, Björkhem I.

J Lipid Res. 1999 Aug;40(8):1417-25.

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