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Items: 1 to 20 of 52

1.

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.

Urra S, Escudero CA, Ramos P, Lisbona F, Allende E, Covarrubias P, Parraguez JI, Zampieri N, Chao MV, Annaert W, Bronfman FC.

J Biol Chem. 2007 Mar 9;282(10):7606-15. Epub 2007 Jan 9.

2.

Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.

Wehrman T, He X, Raab B, Dukipatti A, Blau H, Garcia KC.

Neuron. 2007 Jan 4;53(1):25-38.

3.

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ.

J Neurosci. 2006 Jul 19;26(29):7756-66.

4.

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.

Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD.

Neuron. 2006 Apr 20;50(2):219-32.

5.

TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor.

Geetha T, Kenchappa RS, Wooten MW, Carter BD.

EMBO J. 2005 Nov 16;24(22):3859-68. Epub 2005 Oct 27.

6.

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, Kermani P, Torkin R, Chen ZY, Lee FS, Kraemer RT, Nykjaer A, Hempstead BL.

J Neurosci. 2005 Jun 1;25(22):5455-63.

7.

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains.

Zampieri N, Xu CF, Neubert TA, Chao MV.

J Biol Chem. 2005 Apr 15;280(15):14563-71. Epub 2005 Feb 8.

8.

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

Pedraza CE, Podlesniy P, Vidal N, Arévalo JC, Lee R, Hempstead B, Ferrer I, Iglesias M, Espinet C.

Am J Pathol. 2005 Feb;166(2):533-43.

9.

Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor.

Linggi MS, Burke TL, Williams BB, Harrington A, Kraemer R, Hempstead BL, Yoon SO, Carter BD.

J Biol Chem. 2005 Apr 8;280(14):13801-8. Epub 2005 Jan 24.

10.

Cell type-specific interleukin-1beta signaling in the CNS.

Srinivasan D, Yen JH, Joseph DJ, Friedman W.

J Neurosci. 2004 Jul 21;24(29):6482-8.

11.

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease.

Peng S, Wuu J, Mufson EJ, Fahnestock M.

J Neuropathol Exp Neurol. 2004 Jun;63(6):641-9.

PMID:
15217092
12.

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury.

Harrington AW, Leiner B, Blechschmitt C, Arevalo JC, Lee R, Mörl K, Meyer M, Hempstead BL, Yoon SO, Giehl KM.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6226-30. Epub 2004 Mar 16.

13.

Sortilin is essential for proNGF-induced neuronal cell death.

Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, Hempstead BL, Petersen CM.

Nature. 2004 Feb 26;427(6977):843-8.

PMID:
14985763
14.

A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF.

Gentry JJ, Rutkoski NJ, Burke TL, Carter BD.

J Biol Chem. 2004 Apr 16;279(16):16646-56. Epub 2004 Feb 11.

15.

The p75 neurotrophin receptor: multiple interactors and numerous functions.

Gentry JJ, Barker PA, Carter BD.

Prog Brain Res. 2004;146:25-39. Review.

PMID:
14699954
16.

Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad.

Bhakar AL, Howell JL, Paul CE, Salehi AH, Becker EB, Said F, Bonni A, Barker PA.

J Neurosci. 2003 Dec 10;23(36):11373-81.

17.

Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor.

Kuwako K, Taniura H, Yoshikawa K.

J Biol Chem. 2004 Jan 16;279(3):1703-12. Epub 2003 Oct 29.

18.

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor.

Jung KM, Tan S, Landman N, Petrova K, Murray S, Lewis R, Kim PK, Kim DS, Ryu SH, Chao MV, Kim TW.

J Biol Chem. 2003 Oct 24;278(43):42161-9. Epub 2003 Aug 11.

19.

A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein.

Wong ST, Henley JR, Kanning KC, Huang KH, Bothwell M, Poo MM.

Nat Neurosci. 2002 Dec;5(12):1302-8.

PMID:
12426574
20.

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp.

Wang KC, Kim JA, Sivasankaran R, Segal R, He Z.

Nature. 2002 Nov 7;420(6911):74-8. Epub 2002 Oct 20.

PMID:
12422217

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