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Items: 1 to 20 of 52

1.

Amyloid beta-protein assembly and Alzheimer disease.

Roychaudhuri R, Yang M, Hoshi MM, Teplow DB.

J Biol Chem. 2009 Feb 20;284(8):4749-53. doi: 10.1074/jbc.R800036200. Review. No abstract available.

2.

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.

Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782.

3.

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.

Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM.

J Neurosci. 2008 Jun 18;28(25):6388-92. doi: 10.1523/JNEUROSCI.0364-08.2008.

4.

Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L.

J Biol Chem. 2007 Aug 17;282(33):23818-28.

5.

A beta oligomers - a decade of discovery.

Walsh DM, Selkoe DJ.

J Neurochem. 2007 Jun;101(5):1172-84. Review.

6.

The anti-amyloidogenic effect is exerted against Alzheimer's beta-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure.

Hirohata M, Hasegawa K, Tsutsumi-Yasuhara S, Ohhashi Y, Ookoshi T, Ono K, Yamada M, Naiki H.

Biochemistry. 2007 Feb 20;46(7):1888-99.

PMID:
17253770
7.

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

Haass C, Selkoe DJ.

Nat Rev Mol Cell Biol. 2007 Feb;8(2):101-12. Review.

PMID:
17245412
8.

Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease.

Wang J, Ho L, Zhao Z, Seror I, Humala N, Dickstein DL, Thiyagarajan M, Percival SS, Talcott ST, Pasinetti GM.

FASEB J. 2006 Nov;20(13):2313-20.

PMID:
17077308
9.
10.

A specific amyloid-beta protein assembly in the brain impairs memory.

Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH.

Nature. 2006 Mar 16;440(7082):352-7.

PMID:
16541076
11.
12.

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

Marambaud P, Zhao H, Davies P.

J Biol Chem. 2005 Nov 11;280(45):37377-82.

13.

Curcumin: the story so far.

Sharma RA, Gescher AJ, Steward WP.

Eur J Cancer. 2005 Sep;41(13):1955-68. Review.

PMID:
16081279
14.

Neurotoxic protein oligomers--what you see is not always what you get.

Bitan G, Fradinger EA, Spring SM, Teplow DB.

Amyloid. 2005 Jun;12(2):88-95.

15.

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ.

Nat Med. 2005 May;11(5):556-61.

PMID:
15834427
16.

Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.

Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M.

J Biol Chem. 2005 Mar 4;280(9):7614-23.

17.

Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.

Ono K, Hasegawa K, Naiki H, Yamada M.

Biochim Biophys Acta. 2004 Nov 5;1690(3):193-202.

18.

Alzheimer's disease.

Cummings JL.

N Engl J Med. 2004 Jul 1;351(1):56-67. Review. No abstract available.

PMID:
15229308
19.
20.

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease.

Klein WL, Stine WB Jr, Teplow DB.

Neurobiol Aging. 2004 May-Jun;25(5):569-80. Review.

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