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Items: 1 to 20 of 27

1.

Improvement of the quality of lumazine synthase crystals by protein engineering.

Rodríguez-Fernández L, López-Jaramillo FJ, Bacher A, Fischer M, Weinkauf S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt 7):625-8. doi: 10.1107/S1744309108015728. Epub 2008 Jun 11.

2.

Designed protein-protein association.

Grueninger D, Treiber N, Ziegler MO, Koetter JW, Schulze MS, Schulz GE.

Science. 2008 Jan 11;319(5860):206-9. doi: 10.1126/science.1150421.

3.

A surface on the androgen receptor that allosterically regulates coactivator binding.

Estébanez-Perpiñá E, Arnold LA, Nguyen P, Rodrigues ED, Mar E, Bateman R, Pallai P, Shokat KM, Baxter JD, Guy RK, Webb P, Fletterick RJ.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16074-9. Epub 2007 Oct 2. Erratum in: Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18874. Arnold, Alexander A [corrected to Arnold, Leggy A].

4.

Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor.

Estébanez-Perpiñá E, Arnold LA, Jouravel N, Togashi M, Blethrow J, Mar E, Nguyen P, Phillips KJ, Baxter JD, Webb P, Guy RK, Fletterick RJ.

Mol Endocrinol. 2007 Dec;21(12):2919-28. Epub 2007 Sep 6.

PMID:
17823305
5.

An approach to crystallizing proteins by synthetic symmetrization.

Banatao DR, Cascio D, Crowley CS, Fleissner MR, Tienson HL, Yeates TO.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16230-5. Epub 2006 Oct 18.

6.

Rearrangements in thyroid hormone receptor charge clusters that stabilize bound 3,5',5-triiodo-L-thyronine and inhibit homodimer formation.

Togashi M, Nguyen P, Fletterick R, Baxter JD, Webb P.

J Biol Chem. 2005 Jul 8;280(27):25665-73. Epub 2005 May 10.

7.

Principles for modulation of the nuclear receptor superfamily.

Gronemeyer H, Gustafsson JA, Laudet V.

Nat Rev Drug Discov. 2004 Nov;3(11):950-64. Review.

PMID:
15520817
9.
10.

Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor.

Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, Fletterick RJ.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15358-63. Epub 2003 Dec 12.

11.
12.

Selective modulation of thyroid hormone receptor action.

Baxter JD, Dillmann WH, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS.

J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):31-42. Review.

PMID:
11384861
13.

Definition of the surface in the thyroid hormone receptor ligand binding domain for association as homodimers and heterodimers with retinoid X receptor.

Ribeiro RC, Feng W, Wagner RL, Costa CH, Pereira AC, Apriletti JW, Fletterick RJ, Baxter JD.

J Biol Chem. 2001 May 4;276(18):14987-95. Epub 2001 Jan 5.

14.

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist.

Pike AC, Brzozowski AM, Hubbard RE, Bonn T, Thorsell AG, Engström O, Ljunggren J, Gustafsson JA, Carlquist M.

EMBO J. 1999 Sep 1;18(17):4608-18.

15.

Molecular and structural biology of thyroid hormone receptors.

Apriletti JW, Ribeiro RC, Wagner RL, Feng W, Webb P, Kushner PJ, West BL, Nilsson S, Scanlan TS, Fletterick RJ, Baxter JD.

Clin Exp Pharmacol Physiol Suppl. 1998 Nov;25:S2-11. Review.

PMID:
9809185
16.

Structure and specificity of nuclear receptor-coactivator interactions.

Darimont BD, Wagner RL, Apriletti JW, Stallcup MR, Kushner PJ, Baxter JD, Fletterick RJ, Yamamoto KR.

Genes Dev. 1998 Nov 1;12(21):3343-56.

17.

Thyroid hormone receptor coactivators and corepressors.

Koenig RJ.

Thyroid. 1998 Aug;8(8):703-13. Review.

PMID:
9737367
18.

Molecular basis of agonism and antagonism in the oestrogen receptor.

Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engström O, Ohman L, Greene GL, Gustafsson JA, Carlquist M.

Nature. 1997 Oct 16;389(6652):753-8.

PMID:
9338790
19.

Thyroid hormone-mediated enhancement of heterodimer formation between thyroid hormone receptor beta and retinoid X receptor.

Collingwood TN, Butler A, Tone Y, Clifton-Bligh RJ, Parker MG, Chatterjee VK.

J Biol Chem. 1997 May 16;272(20):13060-5.

20.

Why protein crystals favour some space-groups over others.

Wukovitz SW, Yeates TO.

Nat Struct Biol. 1995 Dec;2(12):1062-7.

PMID:
8846217

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