Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 54

1.

General and versatile autoinhibition of PLC isozymes.

Hicks SN, Jezyk MR, Gershburg S, Seifert JP, Harden TK, Sondek J.

Mol Cell. 2008 Aug 8;31(3):383-94. doi: 10.1016/j.molcel.2008.06.018.

2.

Activation of human phospholipase C-eta2 by Gbetagamma.

Zhou Y, Sondek J, Harden TK.

Biochemistry. 2008 Apr 15;47(15):4410-7. doi: 10.1021/bi800044n. Epub 2008 Mar 25.

3.

Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.

Lutz S, Shankaranarayanan A, Coco C, Ridilla M, Nance MR, Vettel C, Baltus D, Evelyn CR, Neubig RR, Wieland T, Tesmer JJ.

Science. 2007 Dec 21;318(5858):1923-7.

4.

Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation.

Citro S, Malik S, Oestreich EA, Radeff-Huang J, Kelley GG, Smrcka AV, Brown JH.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15543-8. Epub 2007 Sep 18.

5.

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.

Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J.

J Biol Chem. 2007 Oct 5;282(40):29201-10. Epub 2007 Jul 2.

6.

Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes.

Oestreich EA, Wang H, Malik S, Kaproth-Joslin KA, Blaxall BC, Kelley GG, Dirksen RT, Smrcka AV.

J Biol Chem. 2007 Feb 23;282(8):5488-95. Epub 2006 Dec 17.

7.

Crystal structure of Rac1 bound to its effector phospholipase C-beta2.

Jezyk MR, Snyder JT, Gershberg S, Worthylake DK, Harden TK, Sondek J.

Nat Struct Mol Biol. 2006 Dec;13(12):1135-40. Epub 2006 Nov 19.

PMID:
17115053
8.

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

Hinkes B, Wiggins RC, Gbadegesin R, Vlangos CN, Seelow D, Nürnberg G, Garg P, Verma R, Chaib H, Hoskins BE, Ashraf S, Becker C, Hennies HC, Goyal M, Wharram BL, Schachter AD, Mudumana S, Drummond I, Kerjaschki D, Waldherr R, Dietrich A, Ozaltin F, Bakkaloglu A, Cleper R, Basel-Vanagaite L, Pohl M, Griebel M, Tsygin AN, Soylu A, Müller D, Sorli CS, Bunney TD, Katan M, Liu J, Attanasio M, O'toole JF, Hasselbacher K, Mucha B, Otto EA, Airik R, Kispert A, Kelley GG, Smrcka AV, Gudermann T, Holzman LB, Nürnberg P, Hildebrandt F.

Nat Genet. 2006 Dec;38(12):1397-405. Epub 2006 Nov 5.

PMID:
17086182
9.

Phospholipase C epsilon: linking second messengers and small GTPases.

Bunney TD, Katan M.

Trends Cell Biol. 2006 Dec;16(12):640-8. Epub 2006 Nov 7. Review.

PMID:
17085049
10.

Structural and mechanistic insights into ras association domains of phospholipase C epsilon.

Bunney TD, Harris R, Gandarillas NL, Josephs MB, Roe SM, Sorli SC, Paterson HF, Rodrigues-Lima F, Esposito D, Ponting CP, Gierschik P, Pearl LH, Driscoll PC, Katan M.

Mol Cell. 2006 Feb 17;21(4):495-507.

11.

Direct activation of purified phospholipase C epsilon by RhoA studied in reconstituted phospholipid vesicles.

Seifert JP, Snyder JT, Sondek J, Harden TK.

Methods Enzymol. 2006;406:260-71.

PMID:
16472663
12.

Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy.

Wang H, Oestreich EA, Maekawa N, Bullard TA, Vikstrom KL, Dirksen RT, Kelley GG, Blaxall BC, Smrcka AV.

Circ Res. 2005 Dec 9;97(12):1305-13. Epub 2005 Nov 17.

13.

Regulation of protein activities by phosphoinositide phosphates.

Niggli V.

Annu Rev Cell Dev Biol. 2005;21:57-79. Review.

PMID:
16212487
14.

Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases.

Piechulek T, Rehlen T, Walliser C, Vatter P, Moepps B, Gierschik P.

J Biol Chem. 2005 Nov 25;280(47):38923-31. Epub 2005 Sep 19.

15.

Molecular cloning and characterization of PLC-eta2.

Zhou Y, Wing MR, Sondek J, Harden TK.

Biochem J. 2005 Nov 1;391(Pt 3):667-76.

16.

Signaling interplay in Ras superfamily function.

Mitin N, Rossman KL, Der CJ.

Curr Biol. 2005 Jul 26;15(14):R563-74. Review.

17.

Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon.

Tadano M, Edamatsu H, Minamisawa S, Yokoyama U, Ishikawa Y, Suzuki N, Saito H, Wu D, Masago-Toda M, Yamawaki-Kataoka Y, Setsu T, Terashima T, Maeda S, Satoh T, Kataoka T.

Mol Cell Biol. 2005 Mar;25(6):2191-9.

18.

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.

Rossman KL, Der CJ, Sondek J.

Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. Review.

PMID:
15688002
19.

The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.

Lutz S, Freichel-Blomquist A, Yang Y, Rümenapp U, Jakobs KH, Schmidt M, Wieland T.

J Biol Chem. 2005 Mar 25;280(12):11134-9. Epub 2005 Jan 4.

20.

Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.

Bai Y, Edamatsu H, Maeda S, Saito H, Suzuki N, Satoh T, Kataoka T.

Cancer Res. 2004 Dec 15;64(24):8808-10.

Supplemental Content

Support Center