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Items: 1 to 20 of 32

1.

Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

Lawlor DA, Timpson NJ, Harbord RM, Leary S, Ness A, McCarthy MI, Frayling TM, Hattersley AT, Smith GD.

PLoS Med. 2008 Mar 11;5(3):e33. doi: 10.1371/journal.pmed.0050033.

2.

Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach.

Chen L, Smith GD, Harbord RM, Lewis SJ.

PLoS Med. 2008 Mar 4;5(3):e52. doi: 10.1371/journal.pmed.0050052. Review.

3.

Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology.

Smith GD, Lawlor DA, Harbord R, Timpson N, Day I, Ebrahim S.

PLoS Med. 2007 Dec;4(12):e352.

4.

Persistence of contradicted claims in the literature.

Tatsioni A, Bonitsis NG, Ioannidis JP.

JAMA. 2007 Dec 5;298(21):2517-26.

PMID:
18056905
5.

Mendelian randomization: using genes as instruments for making causal inferences in epidemiology.

Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G.

Stat Med. 2008 Apr 15;27(8):1133-63.

PMID:
17886233
6.

A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology.

Bochud M, Chiolero A, Elston RC, Paccaud F.

Int J Epidemiol. 2008 Apr;37(2):414-6; author reply 416-7. Epub 2007 Sep 19. No abstract available.

PMID:
17881410
7.
8.

Capitalizing on Mendelian randomization to assess the effects of treatments.

Davey Smith G.

J R Soc Med. 2007 Sep;100(9):432-5. Review. No abstract available.

9.

Mendelian randomization as an instrumental variable approach to causal inference.

Didelez V, Sheehan N.

Stat Methods Med Res. 2007 Aug;16(4):309-30. Review.

PMID:
17715159
10.

Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case-Cohort Study, 1984-2002.

Herder C, Klopp N, Baumert J, Müller M, Khuseyinova N, Meisinger C, Martin S, Illig T, Koenig W, Thorand B.

Diabetologia. 2008 Feb;51(2):276-84. Epub 2007 Aug 22.

PMID:
17712545
11.

Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study.

Kivimäki M, Lawlor DA, Eklund C, Smith GD, Hurme M, Lehtimäki T, Viikari JS, Raitakari OT.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):978-9. No abstract available.

12.

An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people.

Frayling TM, Rafiq S, Murray A, Hurst AJ, Weedon MN, Henley W, Bandinelli S, Corsi AM, Ferrucci L, Guralnik JM, Wallace RB, Melzer D.

J Gerontol A Biol Sci Med Sci. 2007 Jan;62(1):73-8.

13.

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'.

Keavney B, Danesh J, Parish S, Palmer A, Clark S, Youngman L, Delépine M, Lathrop M, Peto R, Collins R.

Int J Epidemiol. 2006 Aug;35(4):935-43. Epub 2006 Jul 26.

PMID:
16870675
14.

Instruments for causal inference: an epidemiologist's dream?

Hernán MA, Robins JM.

Epidemiology. 2006 Jul;17(4):360-72. Erratum in: Epidemiology. 2014 Jan;25(1):164.

PMID:
16755261
15.

Insight into the nature of the CRP-coronary event association using Mendelian randomization.

Casas JP, Shah T, Cooper J, Hawe E, McMahon AD, Gaffney D, Packard CJ, O'Reilly DS, Juhan-Vague I, Yudkin JS, Tremoli E, Margaglione M, Di Minno G, Hamsten A, Kooistra T, Stephens JW, Hurel SJ, Livingstone S, Colhoun HM, Miller GJ, Bautista LE, Meade T, Sattar N, Humphries SE, Hingorani AD.

Int J Epidemiol. 2006 Aug;35(4):922-31. Epub 2006 Mar 24.

PMID:
16565153
16.

Inferring causal relationships among intermediate phenotypes and biomarkers: a case study of rheumatoid arthritis.

Li W, Wang M, Irigoyen P, Gregersen PK.

Bioinformatics. 2006 Jun 15;22(12):1503-7. Epub 2006 Mar 21.

PMID:
16551663
17.

Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials.

Nitsch D, Molokhia M, Smeeth L, DeStavola BL, Whittaker JC, Leon DA.

Am J Epidemiol. 2006 Mar 1;163(5):397-403. Epub 2006 Jan 12. Review.

PMID:
16410347
18.

C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.

Timpson NJ, Lawlor DA, Harbord RM, Gaunt TR, Day IN, Palmer LJ, Hattersley AT, Ebrahim S, Lowe GD, Rumley A, Davey Smith G.

Lancet. 2005 Dec 3;366(9501):1954-9.

PMID:
16325697
19.

Genetic epidemiology and public health: hope, hype, and future prospects.

Davey Smith G, Ebrahim S, Lewis S, Hansell AL, Palmer LJ, Burton PR.

Lancet. 2005 Oct 22-28;366(9495):1484-98. Review.

PMID:
16243094
20.

Does elevated plasma fibrinogen increase the risk of coronary heart disease? Evidence from a meta-analysis of genetic association studies.

Smith GD, Harbord R, Milton J, Ebrahim S, Sterne JA.

Arterioscler Thromb Vasc Biol. 2005 Oct;25(10):2228-33. Epub 2005 Aug 25.

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