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Items: 1 to 20 of 23

1.

Anesthetic properties of the ketone bodies beta-hydroxybutyric acid and acetone.

Yang L, Zhao J, Milutinovic PS, Brosnan RJ, Eger EI 2nd, Sonner JM.

Anesth Analg. 2007 Sep;105(3):673-9.

PMID:
17717222
2.

Ammonia has anesthetic properties.

Brosnan RJ, Yang L, Milutinovic PS, Zhao J, Laster MJ, Eger EI 2nd, Sonner JM.

Anesth Analg. 2007 Jun;104(6):1430-3, table of contents.

PMID:
17513636
3.

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.

Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL 2nd, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL.

J Pharmacol Exp Ther. 2006 Oct;319(1):208-18. Epub 2006 Jun 28.

4.

Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers.

Brosnan R, Gong D, Cotten J, Keshavaprasad B, Yost CS, Eger EI 2nd, Sonner JM.

Anesth Analg. 2006 Jul;103(1):86-91, table of contents.

PMID:
16790632
5.

Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA.

J Pharmacol Exp Ther. 2006 Jul;318(1):434-43. Epub 2006 Apr 18.

6.
7.

Homology modeling of a human glycine alpha 1 receptor reveals a plausible anesthetic binding site.

Bertaccini EJ, Shapiro J, Brutlag DL, Trudell JR.

J Chem Inf Model. 2005 Jan-Feb;45(1):128-35.

PMID:
15667138
8.

Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration.

Sonner JM, Antognini JF, Dutton RC, Flood P, Gray AT, Harris RA, Homanics GE, Kendig J, Orser B, Raines DE, Rampil IJ, Trudell J, Vissel B, Eger EI 2nd.

Anesth Analg. 2003 Sep;97(3):718-40. Review. Erratum in: Anesth Analg. 2004 Jan;98(1):29.

PMID:
12933393
9.

Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase.

Powers RA, Morandi F, Shoichet BK.

Structure. 2002 Jul;10(7):1013-23.

10.

Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations.

Nishikawa K, Jenkins A, Paraskevakis I, Harrison NL.

Neuropharmacology. 2002 Mar;42(3):337-45.

PMID:
11897112
11.

Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors.

Zuo Y, Aistrup GL, Marszalec W, Gillespie A, Chavez-Noriega LE, Yeh JZ, Narahashi T.

Mol Pharmacol. 2001 Oct;60(4):700-11.

12.

Interactions of anesthetics with the water-hexane interface. A molecular dynamics study.

Chipot C, Wilson MA, Pohorille A.

J Phys Chem B. 1997 Jan 30;101(5):782-91.

PMID:
11542402
13.

Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

Jenkins A, Greenblatt EP, Faulkner HJ, Bertaccini E, Light A, Lin A, Andreasen A, Viner A, Trudell JR, Harrison NL.

J Neurosci. 2001 Mar 15;21(6):RC136.

14.
15.

Selective actions of a detergent on ligand-gated ion channels expressed in Xenopus oocytes.

Machu TK, Mihic SJ, Dildy-Mayfield JE.

J Pharmacol Exp Ther. 1998 Jan;284(1):32-6.

16.

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL.

Nature. 1997 Sep 25;389(6649):385-9.

PMID:
9311780
18.
19.

The lateral pressure profile in membranes: a physical mechanism of general anesthesia.

Cantor RS.

Biochemistry. 1997 Mar 4;36(9):2339-44. Review.

PMID:
9054538
20.

A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors.

Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA.

Mol Pharmacol. 1996 Aug;50(2):402-6.

PMID:
8700149

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