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Atypia in random periareolar fine-needle aspiration affects the decision of women at high risk to take tamoxifen for breast cancer chemoprevention.

Goldenberg VK, Seewaldt VL, Scott V, Bean GR, Broadwater G, Fabian C, Kimler B, Zalles C, Lipkus IM.

Cancer Epidemiol Biomarkers Prev. 2007 May;16(5):1032-4.


Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer.

Wegman P, Elingarami S, Carstensen J, Stål O, Nordenskjöld B, Wingren S.

Breast Cancer Res. 2007;9(1):R7.


Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk.

Bean GR, Ibarra Drendall C, Goldenberg VK, Baker JC Jr, Troch MM, Paisie C, Wilke LG, Yee L, Marcom PK, Kimler BF, Fabian CJ, Zalles CM, Broadwater G, Scott V, Seewaldt VL.

Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):50-6.


The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.

Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Weinshilboum RM, Fritcher EG, Nibbe AM, Desta Z, Nguyen A, Flockhart DA, Perez EA, Ingle JN.

Breast Cancer Res Treat. 2007 Jan;101(1):113-21. Epub 2006 Nov 18.


Long-term raloxifene in a woman at high risk for breast cancer.

Bean GR, Kimler BF, Seewaldt VL.

N Engl J Med. 2006 Oct 12;355(15):1620-2. No abstract available.


Interferon regulatory factor-1 regulates reconstituted extracellular matrix (rECM)-mediated apoptosis in human mammary epithelial cells.

Bowie ML, Troch MM, Delrow J, Dietze EC, Bean GR, Ibarra C, Pandiyan G, Seewaldt VL.

Oncogene. 2007 Mar 29;26(14):2017-26. Epub 2006 Oct 2.


Estrogen receptor expression in benign breast ductal cells obtained from random periareolar fine needle aspiration correlates with menopausal status and cytomorphology index score.

Sharma P, Kimler BF, Warner C, Metheny T, Xue Q, Zalles CM, Fabian CJ.

Breast Cancer Res Treat. 2006 Nov;100(1):71-6. Epub 2006 Jun 22.


Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer.

Lee S, Mohsin SK, Mao S, Hilsenbeck SG, Medina D, Allred DC.

Breast Cancer Res. 2006;8(1):R6. Epub 2005 Dec 16.


CYP2D6 variants and the prediction of tamoxifen response in randomized patients: author response.

Wegman PP, Wingren S.

Breast Cancer Res. 2005 Mar 29;7(6):E7. No abstract available.


Functional implications of altered subcellular localization of PELP1 in breast cancer cells.

Vadlamudi RK, Manavathi B, Balasenthil S, Nair SS, Yang Z, Sahin AA, Kumar R.

Cancer Res. 2005 Sep 1;65(17):7724-32.


Gender difference in estrogen receptor alpha promoter hypermethylation and its prognostic value in non-small cell lung cancer.

Lai JC, Cheng YW, Chiou HL, Wu MF, Chen CY, Lee H.

Int J Cancer. 2005 Dec 20;117(6):974-80.


Retinoic acid receptor-beta2 promoter methylation in random periareolar fine needle aspiration.

Bean GR, Scott V, Yee L, Ratliff-Daniel B, Troch MM, Seo P, Bowie ML, Marcom PK, Slade J, Kimler BF, Fabian CJ, Zalles CM, Broadwater G, Baker JC Jr, Wilke LG, Seewaldt VL.

Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):790-8.


Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells.

Bowie ML, Dietze EC, Delrow J, Bean GR, Troch MM, Marjoram RJ, Seewaldt VL.

Oncogene. 2004 Nov 18;23(54):8743-55.


A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

Raimundo S, Toscano C, Klein K, Fischer J, Griese EU, Eichelbaum M, Schwab M, Zanger UM.

Clin Pharmacol Ther. 2004 Aug;76(2):128-38.


Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.

Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, Laird PW.

Cancer Res. 2004 Jun 1;64(11):3807-13.


Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

Desta Z, Ward BA, Soukhova NV, Flockhart DA.

J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75. Epub 2004 May 24.


Steroid receptors and cell cycle in normal mammary epithelium.

Anderson E, Clarke RB.

J Mammary Gland Biol Neoplasia. 2004 Jan;9(1):3-13. Review.


Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity.

Dietze EC, Troch MM, Bean GR, Heffner JB, Bowie ML, Rosenberg P, Ratliff B, Seewaldt VL.

Oncogene. 2004 May 6;23(21):3851-62.


The epigenome as a target for cancer chemoprevention.

Kopelovich L, Crowell JA, Fay JR.

J Natl Cancer Inst. 2003 Dec 3;95(23):1747-57. Review.


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