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Nucleotide excision repair deficiencies and the somatotropic axis in aging.

Garinis GA.

Hormones (Athens). 2008 Jan-Mar;7(1):9-16. Review.


AGEMAP: a gene expression database for aging in mice.

Zahn JM, Poosala S, Owen AB, Ingram DK, Lustig A, Carter A, Weeraratna AT, Taub DD, Gorospe M, Mazan-Mamczarz K, Lakatta EG, Boheler KR, Xu X, Mattson MP, Falco G, Ko MS, Schlessinger D, Firman J, Kummerfeld SK, Wood WH 3rd, Zonderman AB, Kim SK, Becker KG.

PLoS Genet. 2007 Nov;3(11):e201. Epub 2007 Oct 2.


Motif module map reveals enforcement of aging by continual NF-kappaB activity.

Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY.

Genes Dev. 2007 Dec 15;21(24):3244-57. Epub 2007 Nov 30.


Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis.

Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA.

Science. 2007 Aug 10;317(5839):807-10.


Augmented Wnt signaling in a mammalian model of accelerated aging.

Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, Malide D, Rovira II, Schimel D, Kuo CJ, Gutkind JS, Hwang PM, Finkel T.

Science. 2007 Aug 10;317(5839):803-6.


Evolutionary conservation of regulated longevity assurance mechanisms.

McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D.

Genome Biol. 2007;8(7):R132.


Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

van der Pluijm I, Garinis GA, Brandt RM, Gorgels TG, Wijnhoven SW, Diderich KE, de Wit J, Mitchell JR, van Oostrom C, Beems R, Niedernhofer LJ, Velasco S, Friedberg EC, Tanaka K, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Biol. 2007 Jan;5(1):e2. Erratum in: PLoS Biol. 2008 Nov;6(11):e304.


A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH.

Nature. 2006 Dec 21;444(7122):1038-43.


Mutations that increase the life span of C. elegans inhibit tumor growth.

Pinkston JM, Garigan D, Hansen M, Kenyon C.

Science. 2006 Aug 18;313(5789):971-5.


Biomarkers of aging: combinatorial or systems model?

Kriete A.

Sci Aging Knowledge Environ. 2006 Jan 4;2006(1):pe1.


Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.

Wijnhoven SW, Beems RB, Roodbergen M, van den Berg J, Lohman PH, Diderich K, van der Horst GT, Vijg J, Hoeijmakers JH, van Steeg H.

DNA Repair (Amst). 2005 Nov 21;4(11):1314-24. Epub 2005 Aug 22.


Genetic modulation of senescent phenotypes in Homo sapiens.

Martin GM.

Cell. 2005 Feb 25;120(4):523-32. Review.


Understanding the odd science of aging.

Kirkwood TB.

Cell. 2005 Feb 25;120(4):437-47. Review.


In vivo analysis of growth hormone receptor signaling domains and their associated transcripts.

Rowland JE, Lichanska AM, Kerr LM, White M, d'Aniello EM, Maher SL, Brown R, Teasdale RD, Noakes PG, Waters MJ.

Mol Cell Biol. 2005 Jan;25(1):66-77. Erratum in: Mol Cell Biol. 2005 Mar;25(5):2072.


Life extension in the dwarf mouse.

Bartke A, Brown-Borg H.

Curr Top Dev Biol. 2004;63:189-225. Review.


Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice.

Boylston WH, Gerstner A, DeFord JH, Madsen M, Flurkey K, Harrison DE, Papaconstantinou J.

Aging Cell. 2004 Oct;3(5):283-96.


Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster.

Landis GN, Abdueva D, Skvortsov D, Yang J, Rabin BE, Carrick J, Tavaré S, Tower J.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7663-8. Epub 2004 May 10.


Additive regulation of hepatic gene expression by dwarfism and caloric restriction.

Tsuchiya T, Dhahbi JM, Cui X, Mote PL, Bartke A, Spindler SR.

Physiol Genomics. 2004 May 19;17(3):307-15.


Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.

Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC.

Nat Cell Biol. 2004 Feb;6(2):168-70.


Genetic mouse models of extended lifespan.

Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A.

Exp Gerontol. 2003 Nov-Dec;38(11-12):1353-64. Review.


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