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Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis.

Rawool DB, Bitsaktsis C, Li Y, Gosselin DR, Lin Y, Kurkure NV, Metzger DW, Gosselin EJ.

J Immunol. 2008 Apr 15;180(8):5548-57.


Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia.

Chiavolini D, Alroy J, King CA, Jorth P, Weir S, Madico G, Murphy JR, Wetzler LM.

Infect Immun. 2008 Feb;76(2):486-96. Epub 2007 Nov 19.


Prophylactic and therapeutic use of antibodies for protection against respiratory infection with Francisella tularensis.

Kirimanjeswara GS, Golden JM, Bakshi CS, Metzger DW.

J Immunol. 2007 Jul 1;179(1):532-9.


Immunodominant Francisella tularensis antigens identified using proteome microarray.

Eyles JE, Unal B, Hartley MG, Newstead SL, Flick-Smith H, Prior JL, Oyston PC, Randall A, Mu Y, Hirst S, Molina DM, Davies DH, Milne T, Griffin KF, Baldi P, Titball RW, Felgner PL.

Proteomics. 2007 Jun;7(13):2172-83.


Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes.

Mohapatra NP, Soni S, Bell BL, Warren R, Ernst RK, Muszynski A, Carlson RW, Gunn JS.

Infect Immun. 2007 Jul;75(7):3305-14. Epub 2007 Apr 23.


Animal models of Francisella tularensis infection.

Rick Lyons C, Wu TH.

Ann N Y Acad Sci. 2007 Jun;1105:238-65. Epub 2007 Mar 29. Review.


A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity.

Sebastian S, Dillon ST, Lynch JG, Blalock LT, Balon E, Lee KT, Comstock LE, Conlan JW, Rubin EJ, Tzianabos AO, Kasper DL.

Infect Immun. 2007 May;75(5):2591-602. Epub 2007 Feb 12.


A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice.

Quarry JE, Isherwood KE, Michell SL, Diaper H, Titball RW, Oyston PC.

Vaccine. 2007 Mar 1;25(11):2011-8. Epub 2006 Dec 8.


Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis.

Malik M, Bakshi CS, McCabe K, Catlett SV, Shah A, Singh R, Jackson PL, Gaggar A, Metzger DW, Melendez JA, Blalock JE, Sellati TJ.

J Immunol. 2007 Jan 15;178(2):1013-20.


Role of the wbt locus of Francisella tularensis in lipopolysaccharide O-antigen biogenesis and pathogenicity.

Raynaud C, Meibom KL, Lety MA, Dubail I, Candela T, Frapy E, Charbit A.

Infect Immun. 2007 Jan;75(1):536-41. Epub 2006 Oct 9.


Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge.

Tempel R, Lai XH, Crosa L, Kozlowicz B, Heffron F.

Infect Immun. 2006 Sep;74(9):5095-105.


Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence.

Bakshi CS, Malik M, Regan K, Melendez JA, Metzger DW, Pavlov VM, Sellati TJ.

J Bacteriol. 2006 Sep;188(17):6443-8.


Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence.

Gil H, Platz GJ, Forestal CA, Monfett M, Bakshi CS, Sellati TJ, Furie MB, Benach JL, Thanassi DG.

Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12897-902. Epub 2006 Aug 14.


Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain.

Pechous R, Celli J, Penoske R, Hayes SF, Frank DW, Zahrt TC.

Infect Immun. 2006 Aug;74(8):4452-61.


Immunoproteomic analysis of the murine antibody response to successful and failed immunization with live anti-Francisella vaccines.

Twine SM, Petit MD, Shen H, Mykytczuk NC, Kelly JF, Conlan JW.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):999-1008. Epub 2006 Jun 9. Erratum in: Biochem Biophys Res Commun. 2006 Sep 8;347(4):1171.


In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen.

Twine SM, Mykytczuk NC, Petit MD, Shen H, Sjöstedt A, Wayne Conlan J, Kelly JF.

Biochem Biophys Res Commun. 2006 Jul 14;345(4):1621-33. Epub 2006 May 19.


Toll-like receptor 2 is required for control of pulmonary infection with Francisella tularensis.

Malik M, Bakshi CS, Sahay B, Shah A, Lotz SA, Sellati TJ.

Infect Immun. 2006 Jun;74(6):3657-62.

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