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Items: 1 to 20 of 57


Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.

Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ.

Cancer Cell. 2008 Aug 12;14(2):135-45. doi: 10.1016/j.ccr.2008.07.003.


Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.

Xu Y, Lopes C, Qian Y, Liu Y, Cheng L, Goulding M, Turner EE, Lima D, Ma Q.

J Neurosci. 2008 Apr 9;28(15):4037-46. doi: 10.1523/JNEUROSCI.4126-07.2008.


Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.

Spassky N, Han YG, Aguilar A, Strehl L, Besse L, Laclef C, Ros MR, Garcia-Verdugo JM, Alvarez-Buylla A.

Dev Biol. 2008 May 1;317(1):246-59. doi: 10.1016/j.ydbio.2008.02.026. Epub 2008 Mar 4.


Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.

Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, Schneider-Maunoury S, Alvarez-Buylla A.

Nat Neurosci. 2008 Mar;11(3):277-84. doi: 10.1038/nn2059. Epub 2008 Feb 24.


Mixed lineage leukemia translocations and a leukemia stem cell program.

Faber J, Armstrong SA.

Cancer Res. 2007 Sep 15;67(18):8425-8. Review.


Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Cobaleda C, Jochum W, Busslinger M.

Nature. 2007 Sep 27;449(7161):473-7. Epub 2007 Sep 12.


Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain.

Petryniak MA, Potter GB, Rowitch DH, Rubenstein JL.

Neuron. 2007 Aug 2;55(3):417-33.


Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1.

Salsano E, Croci L, Maderna E, Lupo L, Pollo B, Giordana MT, Consalez GG, Finocchiaro G.

Neuro Oncol. 2007 Jul;9(3):298-307. Epub 2007 May 23.


Modeling the initiation and progression of human acute leukemia in mice.

Barabé F, Kennedy JA, Hope KJ, Dick JE.

Science. 2007 Apr 27;316(5824):600-4.


Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells.

Ehtesham M, Sarangi A, Valadez JG, Chanthaphaychith S, Becher MW, Abel TW, Thompson RC, Cooper MK.

Oncogene. 2007 Aug 23;26(39):5752-61. Epub 2007 Mar 12.


Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.

Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH.

Neuron. 2007 Feb 15;53(4):503-17.


HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.

Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A.

Curr Biol. 2007 Jan 23;17(2):165-72. Epub 2006 Dec 28. Erratum in: Curr Biol. 2007 Jan 23;17(2):192.


Molecular markers of neuronal progenitors in the embryonic cerebellar anlage.

Morales D, Hatten ME.

J Neurosci. 2006 Nov 22;26(47):12226-36.


A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway.

Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP.

Cancer Res. 2006 Oct 15;66(20):10171-8.


Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development.

Fuccillo M, Joyner AL, Fishell G.

Nat Rev Neurosci. 2006 Oct;7(10):772-83. Review. Erratum in: Nat Rev Neurosci. 2006 Nov;7(11):902.


Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA.

Nature. 2006 Aug 17;442(7104):818-22. Epub 2006 Jul 16.


Development of NG2 neural progenitor cells requires Olig gene function.

Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7853-8. Epub 2006 May 8.


Direct visualization of nucleogenesis by precerebellar neurons: involvement of ventricle-directed, radial fibre-associated migration.

Kawauchi D, Taniguchi H, Watanabe H, Saito T, Murakami F.

Development. 2006 Mar;133(6):1113-23.


GFAP-positive progenitor cells produce neurons and oligodendrocytes throughout the CNS.

Casper KB, McCarthy KD.

Mol Cell Neurosci. 2006 Apr;31(4):676-84. Epub 2006 Feb 3.


In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog.

Ahn S, Joyner AL.

Nature. 2005 Oct 6;437(7060):894-7.


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