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J Cutan Pathol. 2005 Jul;32(6):433-7.

Hypertext atlas of dermatopathology with expert system for epithelial tumors of the skin.

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Institute of Pathology, Masaryk University, University Hospital Jihlavska, Brno, Czech Republic.



Image resolution required for reference histological images is high. Obtaining high-resolution images requires a system, composing large image from individual smaller components. Such systems must thus be capable of automatically taking individual image parts, performing shading compensation and fusion of the image parts into one large image. Distribution of such images over the Internet requires developing a suitable user's interface with access to the image details.


The ways of creating high-resolution images (virtual slides) and the interface enabling access to image details using Internet browser are described.


A collection of about 3200 dermatopathological, mostly histologic images is available at Hypertext atlas of dermatopathology. Methods of high-resolution image acquisition were used in digitizing the collection of skin lymphomas (Dermatology Institute, University Hospital, Zurich), which is a part of the atlas. The atlas is continuously maintained and upgraded; the number of contributors is growing.

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