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Items: 1 to 20 of 73

1.

SRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sites.

Lakkaraju AK, Mary C, Scherrer A, Johnson AE, Strub K.

Cell. 2008 May 2;133(3):440-51. doi: 10.1016/j.cell.2008.02.049.

2.

The translocon and the non-specific transport of small molecules in the endoplasmic reticulum (Review).

Lizák B, Csala M, Benedetti A, Bánhegyi G.

Mol Membr Biol. 2008 Feb;25(2):95-101. doi: 10.1080/09687680701670481. Review.

PMID:
18307097
3.
4.

Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation.

MacKinnon AL, Garrison JL, Hegde RS, Taunton J.

J Am Chem Soc. 2007 Nov 28;129(47):14560-1. Epub 2007 Nov 6.

5.

The role of p58IPK in protecting the stressed endoplasmic reticulum.

Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hegde RS.

Mol Biol Cell. 2007 Sep;18(9):3681-91. Epub 2007 Jun 13.

6.

Disease-associated prion protein oligomers inhibit the 26S proteasome.

Kristiansen M, Deriziotis P, Dimcheff DE, Jackson GS, Ovaa H, Naumann H, Clarke AR, van Leeuwen FW, Menéndez-Benito V, Dantuma NP, Portis JL, Collinge J, Tabrizi SJ.

Mol Cell. 2007 Apr 27;26(2):175-88.

7.

Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation.

Nagasawa K, Higashi T, Hosokawa N, Kaufman RJ, Nagata K.

EMBO Rep. 2007 May;8(5):483-9. Epub 2007 Mar 23.

8.

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway.

Kang SW, Rane NS, Kim SJ, Garrison JL, Taunton J, Hegde RS.

Cell. 2006 Dec 1;127(5):999-1013.

9.

Protein transport into the endoplasmic reticulum: mechanisms and pathologies.

Zimmermann R, Müller L, Wullich B.

Trends Mol Med. 2006 Dec;12(12):567-73. Epub 2006 Oct 30.

PMID:
17071140
10.
11.
12.

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.

Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D.

Cell. 2006 Aug 25;126(4):727-39. Erratum in: Cell. 2006 Dec 16;127(6):1284.

13.

The surprising complexity of signal sequences.

Hegde RS, Bernstein HD.

Trends Biochem Sci. 2006 Oct;31(10):563-71. Epub 2006 Aug 21. Review.

PMID:
16919958
14.

Extensive mutational analysis of PRKCSH and SEC63 broadens the spectrum of polycystic liver disease.

Waanders E, te Morsche RH, de Man RA, Jansen JB, Drenth JP.

Hum Mutat. 2006 Aug;27(8):830.

PMID:
16835903
15.

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

Hori O, Miyazaki M, Tamatani T, Ozawa K, Takano K, Okabe M, Ikawa M, Hartmann E, Mai P, Stern DM, Kitao Y, Ogawa S.

Mol Cell Biol. 2006 Jun;26(11):4257-67.

16.

An evolving view of the eukaryotic oligosaccharyltransferase.

Kelleher DJ, Gilmore R.

Glycobiology. 2006 Apr;16(4):47R-62R. Epub 2005 Nov 29. Review.

PMID:
16317064
17.

ERj1p has a basic role in protein biogenesis at the endoplasmic reticulum.

Dudek J, Greiner M, Müller A, Hendershot LM, Kopsch K, Nastainczyk W, Zimmermann R.

Nat Struct Mol Biol. 2005 Nov;12(11):1008-14.

PMID:
16244664
18.

Regulation of protein compartmentalization expands the diversity of protein function.

Shaffer KL, Sharma A, Snapp EL, Hegde RS.

Dev Cell. 2005 Oct;9(4):545-54.

19.

Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1.

Besemer J, Harant H, Wang S, Oberhauser B, Marquardt K, Foster CA, Schreiner EP, de Vries JE, Dascher-Nadel C, Lindley IJ.

Nature. 2005 Jul 14;436(7048):290-3.

PMID:
16015337
20.

A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum.

Garrison JL, Kunkel EJ, Hegde RS, Taunton J.

Nature. 2005 Jul 14;436(7048):285-9.

PMID:
16015336

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