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Items: 1 to 20 of 94


Cell penetrating peptide inhibitors of nuclear factor-kappa B.

Orange JS, May MJ.

Cell Mol Life Sci. 2008 Nov;65(22):3564-91. doi: 10.1007/s00018-008-8222-z. Review.


Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site.

Rushe M, Silvian L, Bixler S, Chen LL, Cheung A, Bowes S, Cuervo H, Berkowitz S, Zheng T, Guckian K, Pellegrini M, Lugovskoy A.

Structure. 2008 May;16(5):798-808. doi: 10.1016/j.str.2008.02.012.


Strong neuroprotection by inhibition of NF-kappaB after neonatal hypoxia-ischemia involves apoptotic mechanisms but is independent of cytokines.

Nijboer CH, Heijnen CJ, Groenendaal F, May MJ, van Bel F, Kavelaars A.

Stroke. 2008 Jul;39(7):2129-37. doi: 10.1161/STROKEAHA.107.504175. Epub 2008 Apr 17.


A dual role of the NF-kappaB pathway in neonatal hypoxic-ischemic brain damage.

Nijboer CH, Heijnen CJ, Groenendaal F, May MJ, van Bel F, Kavelaars A.

Stroke. 2008 Sep;39(9):2578-86. doi: 10.1161/STROKEAHA.108.516401. Epub 2008 Apr 17.


Shared principles in NF-kappaB signaling.

Hayden MS, Ghosh S.

Cell. 2008 Feb 8;132(3):344-62. doi: 10.1016/j.cell.2008.01.020. Review.


High-affinity interaction between IKKbeta and NEMO.

Lo YC, Maddineni U, Chung JY, Rich RL, Myszka DG, Wu H.

Biochemistry. 2008 Mar 11;47(10):3109-16. doi: 10.1021/bi702312c. Epub 2008 Feb 12.


Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide.

Davé SH, Tilstra JS, Matsuoka K, Li F, Karrasch T, Uno JK, Sepulveda AR, Jobin C, Baldwin AS, Robbins PD, Plevy SE.

J Immunol. 2007 Dec 1;179(11):7852-9.


Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease.

Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18754-9. Epub 2007 Nov 13.


Surfactant "fortification" by topical inhibition of nuclear factor-kappaB activity in a newborn piglet lavage model.

von Bismarck P, Klemm K, Wistädt CF, Winoto-Morbach S, Uhlig U, Schütze S, Uhlig S, Lachmann B, Krause MF.

Crit Care Med. 2007 Oct;35(10):2309-18.


Inhibitor kappaB kinase beta binding by inhibitor kappaB kinase gamma.

Drew D, Shimada E, Huynh K, Bergqvist S, Talwar R, Karin M, Ghosh G.

Biochemistry. 2007 Oct 30;46(43):12482-90. Epub 2007 Oct 9.


Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis.

Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M.

J Immunol. 2007 Sep 1;179(5):2681-5.


Protein transduction: identification, characterization and optimization.

Tilstra J, Rehman KK, Hennon T, Plevy SE, Clemens P, Robbins PD.

Biochem Soc Trans. 2007 Aug;35(Pt 4):811-5. Review.


Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes.

Ikeda F, Hecker CM, Rozenknop A, Nordmeier RD, Rogov V, Hofmann K, Akira S, Dötsch V, Dikic I.

EMBO J. 2007 Jul 25;26(14):3451-62. Epub 2007 Jun 28.


Cloning and characterization of an IKK homologue from pearl oyster, Pinctada fucata.

Xiong X, Feng Q, Chen L, Xie L, Zhang R.

Dev Comp Immunol. 2008;32(1):15-25. Epub 2007 Apr 26.


Inhibition of nuclear factor-kappaB ameliorates bowel injury and prolongs survival in a neonatal rat model of necrotizing enterocolitis.

De Plaen IG, Liu SX, Tian R, Neequaye I, May MJ, Han XB, Hsueh W, Jilling T, Lu J, Caplan MS.

Pediatr Res. 2007 Jun;61(6):716-21.


NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex.

Fontan E, Traincard F, Levy SG, Yamaoka S, Véron M, Agou F.

FEBS J. 2007 May;274(10):2540-51. Epub 2007 Apr 10.


Heptad repeats regulate protein phosphatase 2a recruitment to I-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax.

Hong S, Wang LC, Gao X, Kuo YL, Liu B, Merling R, Kung HJ, Shih HM, Giam CZ.

J Biol Chem. 2007 Apr 20;282(16):12119-26. Epub 2007 Feb 21.


Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.

Solt LA, Madge LA, Orange JS, May MJ.

J Biol Chem. 2007 Mar 23;282(12):8724-33. Epub 2007 Jan 23.

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