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Molecular machinery of mitochondrial fusion and fission.

Westermann B.

J Biol Chem. 2008 May 16;283(20):13501-5. doi: 10.1074/jbc.R800011200. Epub 2008 Mar 27. Review. No abstract available.


How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

Chipuk JE, Green DR.

Trends Cell Biol. 2008 Apr;18(4):157-64. doi: 10.1016/j.tcb.2008.01.007. Epub 2008 Mar 7. Review.


Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.

Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, Nunnari J.

Dev Cell. 2008 Feb;14(2):193-204. doi: 10.1016/j.devcel.2007.11.019.


Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.

Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.

EMBO J. 2008 Jan 23;27(2):433-46. doi: 10.1038/sj.emboj.7601963. Epub 2008 Jan 17.


The BCL-2 protein family: opposing activities that mediate cell death.

Youle RJ, Strasser A.

Nat Rev Mol Cell Biol. 2008 Jan;9(1):47-59. Review.


Outer mitochondrial membrane protein degradation by the proteasome.

Neutzner A, Youle RJ, Karbowski M.

Novartis Found Symp. 2007;287:4-14; discussion 14-20. Review.


A genome-wide RNAi screen reveals multiple regulators of caspase activation.

Yi CH, Sogah DK, Boyce M, Degterev A, Christofferson DE, Yuan J.

J Cell Biol. 2007 Nov 19;179(4):619-26. Epub 2007 Nov 12.


Regulation of mitochondrial fusion and division.

Cerveny KL, Tamura Y, Zhang Z, Jensen RE, Sesaki H.

Trends Cell Biol. 2007 Nov;17(11):563-9. Epub 2007 Oct 23. Review.


Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway.

Guo X, Chen KH, Guo Y, Liao H, Tang J, Xiao RP.

Circ Res. 2007 Nov 26;101(11):1113-22. Epub 2007 Sep 27.


Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG.

Nat Cell Biol. 2007 Oct;9(10):1142-51. Epub 2007 Sep 23.


Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis.

Sun MG, Williams J, Munoz-Pinedo C, Perkins GA, Brown JM, Ellisman MH, Green DR, Frey TG.

Nat Cell Biol. 2007 Sep;9(9):1057-65. Epub 2007 Aug 26.


Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.

Griparic L, Kanazawa T, van der Bliek AM.

J Cell Biol. 2007 Aug 27;178(5):757-64. Epub 2007 Aug 20.


OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

Song Z, Chen H, Fiket M, Alexander C, Chan DC.

J Cell Biol. 2007 Aug 27;178(5):749-55. Epub 2007 Aug 20.


Molecular machinery of mitochondrial dynamics in yeast.

Merz S, Hammermeister M, Altmann K, Dürr M, Westermann B.

Biol Chem. 2007 Sep;388(9):917-26. Review.


Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11649-54. Epub 2007 Jul 2.


Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis.

Shen T, Zheng M, Cao C, Chen C, Tang J, Zhang W, Cheng H, Chen KH, Xiao RP.

J Biol Chem. 2007 Aug 10;282(32):23354-61. Epub 2007 Jun 11.


Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence.

Lee S, Jeong SY, Lim WC, Kim S, Park YY, Sun X, Youle RJ, Cho H.

J Biol Chem. 2007 Aug 3;282(31):22977-83. Epub 2007 Jun 1.

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