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Items: 1 to 20 of 87

1.

The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells.

Al-Minawi AZ, Saleh-Gohari N, Helleday T.

Nucleic Acids Res. 2008 Jan;36(1):1-9. Epub 2007 Oct 25.

2.

The nature of telomere fusion and a definition of the critical telomere length in human cells.

Capper R, Britt-Compton B, Tankimanova M, Rowson J, Letsolo B, Man S, Haughton M, Baird DM.

Genes Dev. 2007 Oct 1;21(19):2495-508.

3.

IgH class switching and translocations use a robust non-classical end-joining pathway.

Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW.

Nature. 2007 Sep 27;449(7161):478-82. Epub 2007 Aug 22.

PMID:
17713479
4.

The common biology of cancer and ageing.

Finkel T, Serrano M, Blasco MA.

Nature. 2007 Aug 16;448(7155):767-74. Review.

PMID:
17700693
6.

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.

Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL.

Nature. 2007 Jun 7;447(7145):725-9.

PMID:
17554309
7.

DNA repair is limiting for haematopoietic stem cells during ageing.

Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ.

Nature. 2007 Jun 7;447(7145):686-90.

PMID:
17554302
9.

DNA double-strand break repair: from mechanistic understanding to cancer treatment.

Helleday T, Lo J, van Gent DC, Engelward BP.

DNA Repair (Amst). 2007 Jul 1;6(7):923-35. Epub 2007 Mar 23. Review.

PMID:
17363343
10.

The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIV.

Kuhfittig-Kulle S, Feldmann E, Odersky A, Kuliczkowska A, Goedecke W, Eggert A, Pfeiffer P.

Mutagenesis. 2007 May;22(3):217-33. Epub 2007 Mar 7.

PMID:
17347130
11.

First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure.

Jaspers NG, Raams A, Silengo MC, Wijgers N, Niedernhofer LJ, Robinson AR, Giglia-Mari G, Hoogstraten D, Kleijer WJ, Hoeijmakers JH, Vermeulen W.

Am J Hum Genet. 2007 Mar;80(3):457-66. Epub 2007 Jan 29.

13.

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH.

Nature. 2006 Dec 21;444(7122):1038-43.

PMID:
17183314
14.

Transpositions and translocations induced by site-specific double-strand breaks in budding yeast.

Haber JE.

DNA Repair (Amst). 2006 Sep 8;5(9-10):998-1009. Epub 2006 Jun 27. Review.

PMID:
16807137
15.

Analysis of DNA double-strand break repair pathways in mice.

Brugmans L, Kanaar R, Essers J.

Mutat Res. 2007 Jan 3;614(1-2):95-108. Epub 2006 Jun 23. Review.

PMID:
16797606
16.

Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.

Dollé ME, Busuttil RA, Garcia AM, Wijnhoven S, van Drunen E, Niedernhofer LJ, van der Horst G, Hoeijmakers JH, van Steeg H, Vijg J.

Mutat Res. 2006 Apr 11;596(1-2):22-35. Epub 2006 Feb 10.

PMID:
16472827
17.

Alternative pathways for the repair of RAG-induced DNA breaks.

Weinstock DM, Jasin M.

Mol Cell Biol. 2006 Jan;26(1):131-9.

18.

Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.

Tsodikov OV, Enzlin JH, Schärer OD, Ellenberger T.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11236-41. Epub 2005 Aug 2.

19.

The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells.

Griffin C, Waard Hd, Deans B, Thacker J.

DNA Repair (Amst). 2005 Aug 15;4(9):1019-27.

PMID:
15979950
20.

Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers.

Radford SJ, Goley E, Baxter K, McMahan S, Sekelsky J.

Genetics. 2005 Aug;170(4):1737-45. Epub 2005 Jun 8.

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