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Increased sequence diversity coverage improves detection of HIV-specific T cell responses.

Frahm N, Kaufmann DE, Yusim K, Muldoon M, Kesmir C, Linde CH, Fischer W, Allen TM, Li B, McMahon BH, Faircloth KL, Hewitt HS, Mackey EW, Miura T, Khatri A, Wolinsky S, McMichael A, Funkhouser RK, Walker BD, Brander C, Korber BT.

J Immunol. 2007 Nov 15;179(10):6638-50.


Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals.

Connolly NC, Whiteside TL, Wilson C, Kondragunta V, Rinaldo CR, Riddler SA.

Clin Vaccine Immunol. 2008 Feb;15(2):284-92. Epub 2007 Oct 17.


Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.

Friedrich TC, Valentine LE, Yant LJ, Rakasz EG, Piaskowski SM, Furlott JR, Weisgrau KL, Burwitz B, May GE, León EJ, Soma T, Napoe G, Capuano SV 3rd, Wilson NA, Watkins DI.

J Virol. 2007 Apr;81(7):3465-76. Epub 2007 Jan 24.


Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.

Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD, Hahn BH, Korber BT.

Nat Med. 2007 Jan;13(1):100-6. Epub 2006 Dec 24.


CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.

Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, Reddy S, de Pierres C, Mncube Z, Mkhwanazi N, Bishop K, van der Stok M, Nair K, Khan N, Crawford H, Payne R, Leslie A, Prado J, Prendergast A, Frater J, McCarthy N, Brander C, Learn GH, Nickle D, Rousseau C, Coovadia H, Mullins JI, Heckerman D, Walker BD, Goulder P.

Nat Med. 2007 Jan;13(1):46-53. Epub 2006 Dec 17.


Long-lasting decrease in viremia in macaques chronically infected with simian immunodeficiency virus SIVmac251 after therapeutic DNA immunization.

von Gegerfelt AS, Rosati M, Alicea C, Valentin A, Roth P, Bear J, Franchini G, Albert PS, Bischofberger N, Boyer JD, Weiner DB, Markham P, Israel ZR, Eldridge JH, Pavlakis GN, Felber BK.

J Virol. 2007 Feb;81(4):1972-9. Epub 2006 Nov 29.


MHC class I allele frequencies in pigtail macaques of diverse origin.

Pratt BF, O'Connor DH, Lafont BA, Mankowski JL, Fernandez CS, Triastuti R, Brooks AG, Kent SJ, Smith MZ.

Immunogenetics. 2006 Dec;58(12):995-1001. Epub 2006 Nov 10.


Comparative efficacy of subtype AE simian-human immunodeficiency virus priming and boosting vaccines in pigtail macaques.

De Rose R, Batten CJ, Smith MZ, Fernandez CS, Peut V, Thomson S, Ramshaw IA, Coupar BE, Boyle DB, Venturi V, Davenport MP, Kent SJ.

J Virol. 2007 Jan;81(1):292-300. Epub 2006 Oct 18.


Comparative evaluation of simian, simian-human, and human immunodeficiency virus infections in the pigtail macaque (Macaca nemestrina) model.

Batten CJ, De Rose R, Wilson KM, Agy MB, Chea S, Stratov I, Montefiori DC, Kent SJ.

AIDS Res Hum Retroviruses. 2006 Jun;22(6):580-8.


DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued.

Fuller DH, Rajakumar PA, Wu MS, McMahon CW, Shipley T, Fuller JT, Bazmi A, Trichel AM, Allen TM, Mothe B, Haynes JR, Watkins DI, Murphey-Corb M.

Virology. 2006 Apr 25;348(1):200-15. Epub 2006 Jan 24.


Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.

Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C.

Nat Immunol. 2006 Feb;7(2):173-8. Epub 2005 Dec 20.


The pigtail macaque MHC class I allele Mane-A*10 presents an immundominant SIV Gag epitope: identification, tetramer development and implications of immune escape and reversion.

Smith MZ, Fernandez CS, Chung A, Dale CJ, De Rose R, Lin J, Brooks AG, Krebs KC, Watkins DI, O'Connor DH, Davenport MP, Kent SJ.

J Med Primatol. 2005 Oct;34(5-6):282-93.


Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses.

Reimann KA, Parker RA, Seaman MS, Beaudry K, Beddall M, Peterson L, Williams KC, Veazey RS, Montefiori DC, Mascola JR, Nabel GJ, Letvin NL.

J Virol. 2005 Jul;79(14):8878-85.


Therapeutic immunization with a human immunodeficiency virus (HIV) type 1-recombinant canarypox vaccine in chronically HIV-infected patients: The Vacciter Study (ANRS 094).

Tubiana R, Carcelain G, Vray M, Gourlain K, Dalban C, Chermak A, Rabian C, Vittecoq D, Simon A, Bouvet E, El Habib R, Costagliola D, Calvez V, Autran B, Katlama C; Vacciter Study group.

Vaccine. 2005 Jul 29;23(34):4292-301.


Induction of T-cell immunity to antiretroviral drug-resistant human immunodeficiency virus type 1.

Stratov I, Dale CJ, Chea S, McCluskey J, Kent SJ.

J Virol. 2005 Jun;79(12):7728-37.


Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection.

Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M.

Nature. 2005 Apr 28;434(7037):1093-7.


Enhanced cellular immunity in macaques following a novel peptide immunotherapy.

Chea S, Dale CJ, De Rose R, Ramshaw IA, Kent SJ.

J Virol. 2005 Mar;79(6):3748-57.


Control of viral rebound through therapeutic immunization with DermaVir.

Lisziewicz J, Trocio J, Xu J, Whitman L, Ryder A, Bakare N, Lewis MG, Wagner W, Pistorio A, Arya S, Lori F.

AIDS. 2005 Jan 3;19(1):35-43.


Analysis of pigtail macaque major histocompatibility complex class I molecules presenting immunodominant simian immunodeficiency virus epitopes.

Smith MZ, Dale CJ, De Rose R, Stratov I, Fernandez CS, Brooks AG, Weinfurter J, Krebs K, Riek C, Watkins DI, O'connor DH, Kent SJ.

J Virol. 2005 Jan;79(2):684-95.

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